The first type of toxicity is due to the interaction between Disulfiram and alcohol. The second reason is not to be confused in case of side effects and to be able to attribute the side effect to the causative drug. For Lyme patients on Disulfiram, my recommendation daily is a multi vitamin & mineral supplement and 500 mg of Thiamine, which is water soluble. The monitoring of these metals is recommended.It is very important to be aware that only alcoholic beverages contain alcohol but also many medications, supplements, and other products commonly used may contain traces of alcohol that may interact with Disulfiram. At times, especially at a dose of 500 mg, she experienced intense headaches, fatigue, dizziness and muscle aches which disappeared at day 60.When exerting herself, she noticed an odor similar to onions that some report with use of the drug. Some will give Disulfiram at the beginning only once a week and will progress as tolerated. In this regard, comorbidities like mold and/or heavy metal toxicity should be addressed as well. The first one is that we are not sure that Disulfiram works on other co-infections, especially on Bartonella. “probably safe” for a new medication or for a new indication does not mean safe for all.

The target dose should never be given at the beginning. I was prescribed Amoxicillin 4x daily, and despite teenager-me missing several doses, the absolute worst of the symptoms were passing. You will need to listen to the whole video for my thoughts on Antabuse (disulfiram) as a new treatment for chronic Lyme disease. (Patients on disulfiram are advised to avoid vinegar, fermented foods, and anything with alcohol. Psychosis could also have been due to Herxheimer’s reaction. Only 8 cases of psychosis reported between 1992-2016 in PubMed. She was treated with various oral antibiotics for Lyme and with Mepron (atovaquone) for babesiosis. The fatigue before Disulfiram was 10/10 now 8/10, headaches 10/10 now 8/10, nausea was 10/10 and now 6-7/10. He saw multiple ENTs, neurologists, allergists and one infectious disease specialist at Montefiore, NYC who all diagnosed with chronic sinusitis that resisted Zithromax, amoxicillin, Augmentin, Duricef, and Netipot. At that time, she was also diagnosed with endocarditis, an infection of the inner lining of the heart chambers and valves.Over the next few decades, she had surgeries to address abdominal pain and endured many unexplained symptoms. 2)  Is there any test that may help to predict who may be more susceptible than others to have serious side effects, especially psychosis or neurological complications? or less is 250 mg a day, from 101 to150 Lbs. Secondly, Disulfiram has its own diverse  acute and chronic adverse drug reactions that will be summarized below. (3) Repurposing FDA approved drugs against the human fungal pathogen, Candida albicans   on If Disulfiram is the Cure for Lyme Disease, Should it Be Prescribed to All Lyme Disease Patients? She has some lingering abdominal, eye, and ear pain, but her activities are no longer restricted. The precise effective dose and the duration of therapy are, however, still unknown. One major consequence of the effect of Disulfiram on alcohol metabolism is that any intake of alcohol during the treatment may cause an Antabuse effect. Anyone who’s experienced Lyme disease can tell you that it’s a really tough infection. Lyme disease affecting the cranial nerves or peripheral nervous system. Disulfiram (Tetraethylthiuram Disulfide) in the Treatment of Lyme Disease and Babesiosis: Report of Experience in Three Cases Dr. Liegner was generous enough to spend a couple of hours speaking with representative of a Lyme patient support group about his experiences with prescribing Disulfiram. Persisters are largely responsible for high levels of biofilm impeding the effects of antimicrobials. Disulfiram entirely sterilized the culture—there were no persisters. Disulfiram was also shown to be effective on candida (3)If Disulfiram is the cure for Lyme disease,  should Disulfiram be prescribed to all Lyme disease patients?The efficacy of Disulfiram on Borrelia is so far much higher than any other tested antibiotics.
She noticed a bull’s-eye rash shortly afterward.

Disulfiram dosing in alcoholics was tried in the past at doses up to 3000 mg/day. Those with less efficient detoxification pathways are more likely to experience toxic side effects, so caution is warranted.As for my story? Oral amoxicillin for children 33 kg and under: 30 mg/kg 3 times per day for 21 days. She felt better immediately, so she rapidly increased to 500 mg on the fifth day but dropped to 250 mg after 45 days as she felt the lower dose was equally effective and she had been without symptoms for the previous 20 days.She took disulfiram for 66 days total. The patient came to see me for the first time on July 2019 for multiple symptoms of multiple systems alluding to tick-borne disease but also to mold toxicity with known mold exposure and known sensitivity to mold as symptoms got exacerbated by mold exposure. Dr. Liegner remarks that the beneficial effects may be already noticeable at a very low dose. Disulfiram may need other antimicrobials to be fully effective but this may be at the risk of unwanted side effects. For this, there are at least three reasons.
There are several hypotheses to explain the effect of disulfiram on Borrelia. )Laura had adverse reactions to eating salsa, pickled peppers, and salad dressing–all of which contained vinegar.