Therapy should be initiated with the lowest dosage possible and titrated gradually based on patient response and tolerance in accordance with the individual product package labeling. Common causes include drugs (e.g., alpha-blockers, including tamsulosin [used for treating conditions such as benign prostatic hypertrophy], and diuretics), diseases causing peripheral neuropathy (e.g., diabetes mellitus), Parkinson's disease, and dementia with Lewy bodies. Concomitant use of alcohol, extensive periods of standing, prolonged or intense exercise, and exposure to heat can also precipitate orthostatic hypotension and should be minimized. Proscar (finasteride) is an inhibitor of steroid Type II 5a-reductase, that works by decreasing the amount of a natural body hormone dihydrotestosterone that causes growth of the prostate, and is used to treat symptoms of benign prostatic hyperplasia in men with an enlarged prostate.Proscar is available in generic form.
Protect from light. Evidence increasingly suggests that disorders of postural hemodynamic control increase risk of cardiovascular disease and all-cause mortality. Finasteride interactions: Cytochrome Nafcillin. Therapy with these drugs should be administered cautiously in patients with liver disease as exposure could be higher.Moderate Potential Hazard, Moderate plausibility. Caution is also advised in patients who are dehydrated (e.g., due to severe or prolonged diarrhea or vomiting), since they may be more sensitive to the hypotensive effect of the drugs. --used with other anti-hypertensive drugs can lead to hypotension-potassium salts form other drugs like PCN G can cause severe hyperkalemia & dysrhythmias -digoxin-heparin Available for Android and iOS devices. Finasteride does not interfere with free PSA levels.To interpret serial PSAs, establish a new PSA baseline ≥6 months after treatment initiation and monitor PSA periodically thereafter. Keep container tightly closed and protect from moisture.Proscar: Store below 30°C (86°F). Females of childbearing potential should not touch or handle crushed or broken tablets.• Appropriate use: Other urological diseases (including prostate cancer) should be ruled out before initiating (in benign prostatic hyperplasia [BPH] management). Tamsulosin has not been studied in patients with severe hepatic impairment.Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Assess response at 6-month intervals before adjusting dose, adding additional agents, or switching to alternative therapy (Barbieri 2019; Endocrine Society [Martin 2018]).Oral: May be administered with or without meals. Common side effects of Proscar include However, patients with end-stage renal disease (Clcr <10 mL/min) have not been studied.Moderate Potential Hazard, Moderate plausibility. Available for Android and iOS devices. Objective and subjective signs of relief of benign prostatic hyperplasia, including improvement in urinary flow, reduction in symptoms of urgency, and relief of difficulty in micturition.Use is contraindicated in females of childbearing potential. Orthostatic effects are most common during initiation of therapy and often occur within 90 minutes after the first dose. Not indicated for use in pediatric patients.• Duration of therapy: For BPH, a minimum of 6 months of treatment may be necessary to determine whether an individual will respond to finasteride; for male pattern hair loss, daily use for ≥3 months may be required before benefit is observed (withdrawal of treatment leads to reversal of hair growth effect within 12 months).• Prostate specific antigen monitoring: Reduces prostate specific antigen (PSA) concentration by ~50% within 6 months of treatment. If dizziness, lightheadedness or palpitations occur, the patient should sit or lie down, and seek medical attention if symptoms are recurrent or bothersome.Moderate Potential Hazard, Moderate plausibility. Applies to: Glaucoma/Intraocular Hypertension, CataractsIntraoperative Floppy Iris Syndrome (IFIS) has been observed during cataract and glaucoma surgery in some patients on or previously treated with alpha 1 blockers, including tamsulosin. Pregnant females are advised to avoid contact with crushed or broken tablets.• It is used to help hair growth in male pattern baldness. Adequate contraception is recommended if used off label in the management hirsutism in females associated with polycystic ovary syndrome (ACOG 194 2018). Dutasteride / tamsulosin systemic 0.5 mg / 0.4 mg (C280 0.5/0.4)
Protect from light. Evidence increasingly suggests that disorders of postural hemodynamic control increase risk of cardiovascular disease and all-cause mortality. Finasteride interactions: Cytochrome Nafcillin. Therapy with these drugs should be administered cautiously in patients with liver disease as exposure could be higher.Moderate Potential Hazard, Moderate plausibility. Caution is also advised in patients who are dehydrated (e.g., due to severe or prolonged diarrhea or vomiting), since they may be more sensitive to the hypotensive effect of the drugs. --used with other anti-hypertensive drugs can lead to hypotension-potassium salts form other drugs like PCN G can cause severe hyperkalemia & dysrhythmias -digoxin-heparin Available for Android and iOS devices. Finasteride does not interfere with free PSA levels.To interpret serial PSAs, establish a new PSA baseline ≥6 months after treatment initiation and monitor PSA periodically thereafter. Keep container tightly closed and protect from moisture.Proscar: Store below 30°C (86°F). Females of childbearing potential should not touch or handle crushed or broken tablets.• Appropriate use: Other urological diseases (including prostate cancer) should be ruled out before initiating (in benign prostatic hyperplasia [BPH] management). Tamsulosin has not been studied in patients with severe hepatic impairment.Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Assess response at 6-month intervals before adjusting dose, adding additional agents, or switching to alternative therapy (Barbieri 2019; Endocrine Society [Martin 2018]).Oral: May be administered with or without meals. Common side effects of Proscar include However, patients with end-stage renal disease (Clcr <10 mL/min) have not been studied.Moderate Potential Hazard, Moderate plausibility. Available for Android and iOS devices. Objective and subjective signs of relief of benign prostatic hyperplasia, including improvement in urinary flow, reduction in symptoms of urgency, and relief of difficulty in micturition.Use is contraindicated in females of childbearing potential. Orthostatic effects are most common during initiation of therapy and often occur within 90 minutes after the first dose. Not indicated for use in pediatric patients.• Duration of therapy: For BPH, a minimum of 6 months of treatment may be necessary to determine whether an individual will respond to finasteride; for male pattern hair loss, daily use for ≥3 months may be required before benefit is observed (withdrawal of treatment leads to reversal of hair growth effect within 12 months).• Prostate specific antigen monitoring: Reduces prostate specific antigen (PSA) concentration by ~50% within 6 months of treatment. If dizziness, lightheadedness or palpitations occur, the patient should sit or lie down, and seek medical attention if symptoms are recurrent or bothersome.Moderate Potential Hazard, Moderate plausibility. Applies to: Glaucoma/Intraocular Hypertension, CataractsIntraoperative Floppy Iris Syndrome (IFIS) has been observed during cataract and glaucoma surgery in some patients on or previously treated with alpha 1 blockers, including tamsulosin. Pregnant females are advised to avoid contact with crushed or broken tablets.• It is used to help hair growth in male pattern baldness. Adequate contraception is recommended if used off label in the management hirsutism in females associated with polycystic ovary syndrome (ACOG 194 2018). Dutasteride / tamsulosin systemic 0.5 mg / 0.4 mg (C280 0.5/0.4)