Patients should be monitored for signs and symptoms of myopathy.Drugs that are inducers of CYP3A (e.g. Studies performed in rats at oral doses up to 500 mg/kg/day (highest dose associated with overt renal toxicity) demonstrated no evidence for clarithromycin-related adverse effects on male fertility. Caution is required if clarithromycin is co-administered with other drugs known to be CYP3A enzyme substrates, especially if the CYP3A substrate has a narrow safety margin (e.g. Monitoring the patient for increased CNS pharmacological effects is suggested (see section 4.5).There have been rare reports of clarithromycin ER tablets in the stool, many of which have occurred in patients with anatomic (including ileostomy or colostomy) or functional gastrointestinal disorders with shortened GI transit times. The recommended daily dosage of Klaricid Paediatric Suspension 125mg/5ml in children is given in the following table and is based on a 7.5mg/kg b.i.d. Reduction of sildenafil, tadalafil and vardenafil dosages should be considered when these drugs are co-administered with clarithromycin.Results of clinical studies indicate that there was a modest but statistically significant (p≤ 0.05) increase of circulating theophylline or carbamazepine levels when either of these drugs were administered concomitantly with clarithromycin. The metabolite is less active than the parent compound for most organisms, including mycobacterium spp. It is used to treat infections such as: 1. pharyngitis, sinusitis).- Skin and soft tissue infections (e.g. For benzodiazepines which are not dependent on CYP3A for their elimination (temazepam, nitrazepam, lorazepam), a clinically important interaction with clarithromycin is unlikely.There have been post-marketing reports of drug interactions and central nervous system (CNS) effects (e.g., somnolence and confusion) with the concomitant use of clarithromycin and triazolam. An overdose of Klaricid Paediatric Suspension 125mg/5ml is likely to cause vomiting and stomach pains.If you forget to give Klaricid Paediatric Suspension 125mg/5mlIf you forget to give your child a dose of medicine, give one as soon as you remember.Do not give more Klaricid Paediatric Suspension 125mg/5ml in one day than your doctor tells you to.If you stop giving Klaricid Paediatric Suspension 125mg/5mlDo not stop giving this medicine even if your child feels better.
Food does slightly delay the onset of absorption of clarithromycin and formation of the 14-hydroxy metabolite. 19818.08.01 klaricid od con.r.tab 500mg/tab btx6(blist1x6) 5,17 € 5,94 € 8,18 € bgp Προϊόντα Μ.Ε.Π.Ε. You should not use this information on this web site or the information on links from this site to diagnose or treat a health problem or disease without consulting with a …
Electrocardiograms should be monitored for QT prolongation during co-administration of clarithromycin with these drugs. Dans ce cas, il faut immédiatement prendre contact avec son médecin traitant.Les patients qui doivent prendre pendant assez longtemps des doses fortes de Klacid peuvent en outre présenter les effets secondaires suivants: flatulences, constipation et sécheresse de la bouche.Si des effets indésirables persistent longtemps ou sont assez sérieux (par exemple diarrhée), signalez-les à votre médecin ou à votre pharmacien.Si vous remarquez d?autres effets secondaires, veuillez-en informer votre médecin ou votre pharmacien.Le médicament ne doit pas être utilisé au-delà de la date figurant après la mention «EXP» sur le récipient.Conserver le Klacid dans son emballage d?origine fermé, à température ambiante (15?25 °C) et hors de portée des enfants.Après la fin du traitement, rapporter le reste du médicament au médecin ou pharmacien, qui se chargera de sa destruction correcte.Pour de plus amples renseignements, consultez votre médecin ou pharmacien.
5-10% of the parent drug is recovered from the faeces.Clarithromycin provides tissue concentrations that are several times higher than circulating drug level. In situations where the concomitant use of clarithromycin with statins cannot be avoided, it is recommended to prescribe the lowest registered dose of the statin.