Prazosin may also be used for other purposes not listed in this medication guide.Follow all directions on your medicine label and package. If priapism is not treated immediately, penile tissue damage and permanent loss of potency could result.Intraoperative Floppy Iris Syndrome (IFIS) has been observed during cataract surgery in some patients treated with alpha-1 blockers. Syncopal episodes have usually occurred within 30 to 90 minutes of the initial dose of the drug; occasionally, they have been reported in association with rapid dosage increases or the introduction of another antihypertensive drug into the regimen of a patient taking high doses of Prazosin hydrochloride. The patient should also be cautioned to avoid situations where injury could result should syncope occur during the initiation of Prazosin hydrochloride therapy.Prolonged erections and priapism have been reported with alpha-1 blockers including Prazosin in post marketing experience. PDR Drug Summaries are concise point-of-care prescribing, dosing and administering information to help phsyicans more efficiently and accurately prescribe in their practice PDR's drug summaries are available free of charge and serve as a great resource for US based MDs, DOs, NPs and PAs in patient practice
In most instances, side effects have disappeared with continued therapy or have been tolerated with no decrease in dose of drug.Less frequent adverse reactions which are reported to occur in 1% to 4% of patients are:In addition, fewer than 1% of patients have reported the following (in some instances, exact causal relationships have not been established):Single reports of pigmentary mottling and serous retinopathy, and a few reports of cataract development or disappearance have been reported. In these instances, the exact causal relationship has not been established because the baseline observations were frequently inadequate.In more specific slit-lamp and funduscopic studies, which included adequate baseline examinations, no drug-related abnormal ophthalmological findings have been reported.Literature reports exist associating Prazosin hydrochloride therapy with a worsening of preexisting narcolepsy. Tell each of your healthcare providers about all your medical conditions, You should not use prazosin if you are allergic to it.Tell your doctor if you are pregnant or plan to become pregnant. A prolonged erection (This is not a complete list of side effects and others may occur. Pharmacology, adverse reactions, warnings and side effects. Your doctor may occasionally change your dose. No decrease in blood pressure was noted. The results of dog forelimb experiments demonstrate that the peripheral vasodilator effect of Prazosin is confined mainly to the level of the resistance vessels (arterioles). However, having high blood pressure during pregnancy may cause complications such as diabetes or eclampsia (dangerously high blood pressure that can lead to medical problems in both mother and baby). A class of drugs is a group of medications that work in a similar way. Therapy with Prazosin was continued for as long as 14 weeks.Prazosin has also been used alone or in combination with other hypotensive agents in severe hypertension of pregnancy by other investigators. There is no measurable negative chronotropic effect.In clinical studies to date, Prazosin hydrochloride has not increased plasma renin activity.In man, blood pressure is lowered in both the supine and standing positions. As with all alpha-blockers, Prazosin hydrochloride may cause syncope with sudden loss of consciousness. Prazosin causes a decrease in total peripheral resistance and was originally thought to have a direct relaxant action on vascular smooth muscle. High blood pressure often has no symptoms. Methods: The study comprised 121 patients with symptomatic BPH who were randomized to … Check with your physician if you have any questions.Prazosin hydrochloride has been administered without any adverse drug interaction in limited clinical experience to date with the following: (1) cardiac glycosides-digitalis and digoxin; (2) hypoglycemics-insulin, chlorpropamide, phenformin, tolazamide, and tolbutamide; (3) tranquilizers and sedatives-chlordiazepoxide, diazepam, and phenobarbital; (4) antigout-allopurinol, colchicine, and probenecid; (5) antiarrhythmics-procainamide, propranolol (see WARNINGS however), and quinidine; and (6) analgesics, antipyretics and anti-inflammatories-propoxyphene, aspirin, indomethacin, and phenylbutazone.Addition of a diuretic or other antihypertensive agent to Prazosin hydrochloride has been shown to cause an additive hypotensive effect.
Prazosin systemic 1 mg (MYLAN 1101 MYLAN 1101) The benefit of treating hypertension may outweigh any risks to the baby.It may not be safe to breastfeed while using this medicine. During these trials and subsequent marketing experience, the most frequent reactions associated with Prazosin hydrochloride therapy are: dizziness 10.3%, headache 7.8%, drowsiness 7.6%, lack of energy 6.9%, weakness 6.5%, palpitations 5.3%, and nausea 4.9%.