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0000014939 00000 n Sotalol hydrochloride is a white, crystalline solid with a molecular weight of 308.8. �� � w !1AQaq"2�B���� #3R�br� trailer /Type /ExtGState 0000015680 00000 n << Easy to read FDA package insert, drug facts, dosage and administration, and adverse effects for Betapace (Sotalol) [/Pattern /DeviceRGB] 0000002452 00000 n /Subtype /Image Cordarone X ® Amiodarone hydrochloride ... flecainide and sotalol • fentanyl (a medicine used to treat pain) • sildenafil (Viagra) • triazolam (a medicine used to treat insomnia) • ergotamine (a medicine used to treat migraine) • general anaesthesia • lignocaine (a topical anaesthetic) • amphotericin B (a medicine used to treat fungal infections) • antiviral medication eg sofosbuvir, daclatasvir, simeprevir, ledipasvir … ��Y� N�����Z8���'I�9���v������O�,���J=-�Bn��m2��r�{\�q�踴������V��!�SCm�k�5#]A_45�W7oouO� �v���_�>mw������SC�S����v�2�)y6@dV%+ /Title (�� S o t a l o l H y d r o c h l o r i d e T a b l e t s , U S P \( A F \) 8 0 m g , 1 2 0 m g , a n d 1 6 0 m g) /CA 1.0 0000014246 00000 n 1372 44 0000010276 00000 n 0000002915 00000 n /SMask /None>> 0000003535 00000 n Amiodarone: (Major) Sotalol administration is associated with a well-established risk of QT prolongation and torsades de pointes (TdP). ?g�IG�?���_�]��_���$�Ɵ�x���.����E~B�~�?�����ҿ���G��~��T��<9� ������a�Y�|ZӮ仺� $(����|�����+�/�!��_��+� �.^�O��V��M����g�t�� ���|�>�� Ventricular tachycardia, including torsade de pointes and monomorphic ventricular tachycardia can occur with excessive prolongation of the QT interval. 0000007762 00000 n Sotalol hydrochloride is a white, crystalline solid with a molecular weight of 308.8. 0000004633 00000 n 3 0 obj << 0000026776 00000 n 0000091466 00000 n 0000090397 00000 n /Producer (�� w k h t m l t o p d f) 0000005902 00000 n oGM� �=X�W��! �� C�� ]�" �� xڜR]HQ>swv�ٔ���$!���S��B��*S���H�+4�)�TR�"VVP���=� It is supplied as a white, capsule-shaped tablet for oral administration. Sotalol hydrochloride injection is an aqueous formulation of sotalol hydrochloride for intravenous use. 4 0 obj patient package insert, dosing administration and safety information). 9 0 obj 1372 0 obj <> endobj 0000005139 00000 n endobj 0000005390 00000 n 0000004194 00000 n 0000017360 00000 n /AIS false 0000029702 00000 n /Height 93
0000005981 00000 n 0000002183 00000 n ~��#����/kڥ�6��M6�H7Ȟ|i6� It is hydrophilic, soluble in water, propylene glycol and ethanol, but is only slightly soluble in chloroform.
0000015049 00000 n /BitsPerComponent 8 Sotalol is an antiarrhythmic drug with Class II (beta-adrenoreceptor blocking) and Class III (cardiac action potential duration prolongation) properties. /Creator (��) stream >> 0000010839 00000 n 0000016705 00000 n
/Length 10 0 R 0000001974 00000 n 0000027007 00000 n Sotalol hydrochloride is a white, … /CreationDate (D:20200225163339-05'00') 0000090611 00000 n 0000015917 00000 n xref 0000000016 00000 n 0000004388 00000 n %%EOF It is supplied as a white to off-white, capsule-shaped, scored tablet for oral administration. Ɗ�/����J%�F���Kg~V}�;ý�����ν� �` Sotalol hydrochloride tablets, USP are an antiarrhythmic drug with Class II (beta-adrenoreceptor blocking) and Class III (cardiac action potential duration prolongation) properties. /SM 0.02 Drugs that prolong the QT interval should be used with extreme caution in combination with sotalol. %&'()*456789:CDEFGHIJSTUVWXYZcdefghijstuvwxyz��������������������������������������������������������������������������� 0000009818 00000 n $4�%�&'()*56789:CDEFGHIJSTUVWXYZcdefghijstuvwxyz�������������������������������������������������������������������������� ? Proarrhythmia in Ventricular Arrhythmia Patients: [see Sotalol Hydrochloride Package Insert] In patients with a history of sustained ventricular tachycardia, the incidence of torsade de pointes during sotalol treatment was 4% and worsened VT in about 1%; in patients with other less serious ventricular arrhythmias the incidence of torsade de pointes was 1% and new or worsened VT in about …