No increased risk was observed in 3 studies assessing the risk of infant cancer after exposure to this drug during pregnancy; however, these studies had limited ability to detect such a signal. WebMD provides important information about Metronidazole Oral such as if you can you take Metronidazole Oral when you are pregnant or nursing or If Metronidazole … This is called her background risk. Follow your doctor's orders or the directions on the label. Antibiotics Might Lower Effectiveness of Birth Control Pill For some conditions, metronidazole is the only drug of choice and it is especially important to treat vaginal infections during pregnancy.Metronidazole gets into breast milk in relatively large amounts, with some reports of up to 20% of the mother’s dose. For more information, please see the MotherToBaby fact sheet Paternal Exposures and Pregnancy at Dr. Carey is Professor and Vice Chair of Academic Affairs in the Department of Pediatrics at the University of Utah and founder and medical director of MotherToBaby Utah’s Pregnancy Risk Line. There is one large study that looked at over 4000 pregnancies with exposure to metronidazole early in pregnancy and did not find an increased risk for miscarriage. Amounts in breast milk would be lower with vaginal or topical use by the mother. It is available in oral, rectal, topical, vaginal and intravenous (I.V.)
Be sure to talk to your healthcare provider about all of your breastfeeding questions.There are currently no studies in humans to suggest that use of metronidazole by the father would negatively affect the sperm or increase the risk for birth defects. However, this dose is below the therapeutic dose given to treat young infants who were able to tolerate this drug with minimal side effects.
In every pregnancy, a woman starts out with a 3-5% chance of having a baby with a birth defect. Cases of candidal infections and diarrhea have been reported; a comparative trial suggested oral and rectal colonization with Candida might be more common in infants exposed to this drug.A decision should be made to discontinue breastfeeding or discontinue the drug, taking into account the importance of the drug to the mother.Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. If your dose is different, do not change it unless your doctor tells you to do so.The amount of medicine that you take depends on the strength of the medicine. Not recommended during pregnancy or while breastfeeding. The dose of this medicine will be different for different patients. There are also reports on breastfed babies who did not have clinical effects while their mothers were taking metronidazole. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the m… After a breastfeeding mother has taken metronidazole, the infant may experience loose stools, especially when the drug is given directly into a vein (intravenously). In addition to his clinical work, Dr. Carey’s research focus has been in congenital malformations, neurofibromatosis and syndrome delineation. preparations. The current data do not support an increased risk for birth defects or other harmful effects on the baby.Metronidazole that is used on skin (topical preparations) is minimally absorbed and not likely to result in significant levels in your blood. He has authored or co‐authored over 280 papers, chapters, invited articles and editorials for scientific journals. If you take antacids containing magnesium or aluminum, iron supplements , or vitamin/mineral products, take them at …
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The following information includes only the average doses of this medicine. Therefore, it is wise to be sure about your pregnancy in case you have an infection and have to take antibiotic treatment to prevent any possible complications in the future. One study with 53 women who used metronidazole did report a greater chance for miscarriage, but it is not clear if the miscarriage risk was from the medication or the underlying infection being treated. Published data include more than 5000 pregnant women who used this drug during pregnancy (many during the first trimester); 1 study showed increased risk of cleft lip (with or without cleft palate) in infants exposed in utero, but these findings were not confirmed.