Clindamycin phosphate is a water soluble ester of the semi-synthetic antibiotic produced by a 7(S)- chloro-substitution of the 7(R)-hydroxyl group of the parent antibiotic lincomycin. Therefore it should be used with caution in patients receiving such agents.In clinical trials with pregnant women, the systemic administration of clindamycin during the second and third trimesters has not been associated with an increased frequency of congenital abnormalities. You may report side effects to Viona Pharmaceuticals Inc. at 1-888-304-5011 or FDA at 1-800-FDA-1088.

Avoid exposure to heat, fire, flame, and smoking. This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions. There are no adequate studies in pregnant women during the first trimester of pregnancy. A comparative study of the pharmacokinetics of Duac Topical Gel and 1% clindamycin solution alone in 78 patients indicated that mean plasma clindamycin levels during the four week dosing period were < 0.5 ng/mL for both treatment groups. Advertising on our site helps support our mission. Clindamycin phosphate topical solution, for external use, contains clindamycin phosphate at a concentration equivalent to 10 mg clindamycin per milliliter in a hydroalcoholic solution. Clindamycin phosphate is a water soluble ester of the semi-synthetic antibiotic produced by a 7(S)-chloro-substitution of the 7(R)-hydroxyl group of the parent antibiotic lincomycin.Clindamycin phosphate topical solution USP, 1% contains isopropyl alcohol, 50% v/v; propylene glycol and purified water. The developmental and health benefits of breastfeeding should be considered along with the mother's clinical need for clindamycin and any potential adverse effects on the breast-fed child from clindamycin or from the underlying maternal condition.If used during lactation and clindamycin phosphate topical solution is applied to the chest, care should be taken to avoid accidental ingestion by the infant.Safety and effectiveness in pediatric patients under the age of 12 have not been established.Clinical studies for Clindamycin Phosphate did not include sufficient numbers of subjects aged 65 and over to determine whether they respond differently from younger subjects. 72578-084-03 Call your doctor for medical advice about side effects. Do not skip doses or stop your medicine early.Talk to your pediatrician regarding the use of this medicine in children. | CLINDAMYCIN (KLIN da MYE sin) is a lincosamide antibiotic. Clindamycin phosphate topical solution should be prescribed with caution in atopic individuals.Clindamycin has been shown to have neuromuscular blocking properties that may enhance the action of other neuromuscular blocking agents. Due to inconsistencies between the drug labels on DailyMed and the pill images provided by Wash affected area and gently pat dry. Diarrhea, bloody diarrhea, and colitis (including pseudomembranous colitis) have been reported with the use of topical and systemic clindamycin.Studies indicate a toxin(s) produced by clostridia is one primary cause of antibiotic-associated colitis. CLINDAMYCIN PHOSPHATE Savings, Coupons and Information. Clindamycin: Topical clindamycin has been shown to be systemically absorbed, but the amount is minimal. Do not freeze. Clindamycin phosphate topical solution USP, 1% contains clindamycin phosphate, USP, at a concentration equivalent to 10 mg clindamycin per milliliter. It is used on the skin to stop the growth of certain bacteria that cause acne.This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.They need to know if you have any of these conditions:This medicine is for external use only. Do not share this medicine with others.If you miss a dose, use it as soon as you can. Sodium hydroxide or hydrochloric acid may be added to adjust pH between 4.0 to 7.0.The mechanism of action of clindamycin in treating acne vulgaris is unknown.Following multiple topical applications of clindamycin phosphate at a concentration equivalent to 10 mg clindamycin per mL in an isopropyl alcohol and water solution, very low levels of clindamycin are present in the serum (0 to 3 ng/mL) and less than 0.2% of the dose is recovered in urine as clindamycin.Clindamycin inhibits bacterial protein synthesis by binding to the 23S RNA of the 50S subunit of the ribosome. Orally and parenterally administered clindamycin has been associated with severe colitis which may result in patient death. However, orally and parenterally administered clindamycin has been reported to appear in breast milk. Clindamycin phosphate is a water soluble ester of the semi-synthetic antibiotic produced by a 7(S)-chloro-substitution of the 7(R)-hydroxyl group of the parent antibiotic lincomycin. We do not endorse non-Cleveland Clinic products or services.