Financials Hi there, A moderate drug interaction can occur between Cymbalta and Lyrica.
Education is a start. Stopping Cymbalta: Even though such side effects are scary, there is another problem with Cymbalta. Cymbalta is not specifically indicated for geriatric depression. A secondary analysis was conducted to measure anxiety using anxiety items 10 (psychic) and 11 (somatic,) and the anxiety/somatization subscale of the HAMD17. In clinical studies of Cymbalta in these patients, the most common side effects were nausea, sleepiness, dizziness, constipation, dry mouth, increased sweating, decreased appetite, and loss of strength or energy. - Patients 75 and older treated with Cymbalta showed significant improvements in psychic anxiety, as well. Some people may find themselves more frustrated, irritable or lacking in patience when taking the drug. Newsletter. Based on pre-clinical studies, Cymbalta is a balanced and potent reuptake inhibitor of serotonin and norepinephrine. Cymbalta Side Effects. “Raising serotonin levels a certain amount can be helpful, but a lot can cause toxicity and even kill you,” explains Saltz. This is not a complete list of side effects and others may occur. Cymbalta also significantly reduced somatic anxiety -- or physical symptoms often associated with anxiety -- compared with placebo (mean change of 1.88 vs. 0.99), according to the anxiety/somatization subscale of the HAMD17. There may be an increase in central nervous system- and/or respiratory-depressant effects especially in elderly or debilitated patients. “Some people be more sensitive to side effects, and some people will have none at all,” says Saltz. * A statistically significant improvement in the somatic anxiety item of the HAMD17 was not seen in patients treated with Cymbalta. Dry Mouth 7. Find patient medical information for Cymbalta Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. But if you already have borderline or Some people experience light-headedness or dizziness, especially when they first start Cymbalta. While on these drugs patients should be monitored for excessive or prolonged CNS and respiratory depression. Cymbalta works to rebalance certain chemicals in the brain that are connected with depression, anxiety and pain. Serotonin and norepinephrine are two chemicals in the brain and spinal cord called neurotransmitters. “Any of these drugs may increase suicidal thoughts in periods of time when there’s a big shift—when you’re starting or raising a dose,” says Saltz. All rights reserved.
Cymbalta (duloxetine) belongs to the class of antidepressants called a selective serotonin and norepinephrine reuptake inhibitors (SNRIs).
"When anxiety symptoms appear in elderly patients with depression it often makes treatment more complicated than when these symptoms emerge alone. “The numbers aren’t big, so we don’t know who will be affected.” No getting around this one: Pretty much all antidepressants have the potential to zap your sex drive. Excessive Sweating 8. Call the doctor if you have thoughts of suicide, or if any of these symptoms are severe or occur suddenly. Certain other drugs, including some OTC ones, can also potentially interact with Cymbalta and be hard on your liver. While depression alone affects two million Americans aged 65 and older(i), there is considerable overlap between depression and anxiety. “It’s not that you wouldn’t be prescribed an antidepressant, but you really want to be cautious. In fact, If it does, your doctor might try decreasing your dose and/or your therapist may offer behavioral tricks to get around it. Reports of soaking through T-shirts 24 hours a day, or extremely sweaty palms or feet may force treatment discontinuation in some people. But menopause can be positive. If it continues, or really bothers you, definitely check in with your doctor.Both medications and alcohol are metabolized—i.e. Available at http://www.jhu.edu/hurj/issue2/07C%20MajorDepress.pdf . Colleen de Bellefonds is an American freelance journalist living in Paris, France, with her husband and dog, Mochi. These side effects may go away during treatment as your body adjusts to the medicine. Reports of soaking through T-shirts 24 hours a day, or extremely sweaty palms or feet may force treatment discontinuation in some people.Cymbalta may also cause vision changes, a dry mouth, nausea and Seizures are listed as a rare but serious side effect of Cymbalta, occurring in roughly 3 out of every 10,500 patients.
Headquartered in Indianapolis, Ind., Lilly provides answers -- through medicines and information -- for some of the world's most urgent medical needs. All rights reserved. Accessed 1/5/05. Abruptly stopping is much more likely to produce symptoms,” she says.This may be because Cymbalta can worse or cause symptoms including anxiety, agitation, panic attacks, insomnia, irritability, hostility, aggressiveness, impulsivity, hypomania, and mania. Families and caregivers should discuss with the doctor any observations of worsening depression symptoms, suicidal thinking and behavior, or unusual changes in behavior. One The longer you’re on Cymbalta, the more likely it is to be an issue.