Other medical conditions that often improve after surgery include heartburn, arthritis, and other joint and circulation problems. Exercise is an ideal method of battling excess weight gain. If Depakote-induced cognitive impairment occurs along with increased appetite and/or food cravings – this combination might prove too overwhelming for some users to manage such that they overeat and gain weight.Fatigue and low energy might lead a person to exercise less frequently, intensely, or for a shorter duration than they did pre-treatment. Significant Weight Loss Some people may experience more serious side effects from taking Depakote such as major liver damage or inflammation of the pancreas, both of which could be fatal. Many people resolve to lose weight in the New Year for different reasons. In addition to the weight gain, the patient experienced a change in natural hair color (from light blonde to dark) and style (it became thicker, darker, and curlier).The patient had been using valproic acid at a dosage of 1000 mg per day and exhibited a serum concentration of 138.9 mcg/ml. Cases of life-threatening pancreatitis have been reported in both children and adults receiving valproate short-term or long-term; symptoms include abdominal pain, nausea, vomiting, and weight loss. I used to weigh 120 lbs. Whereas a study by Corman et al. Ex-vivo studies support the idea that valproic acid directly stimulates pancreatic beta cells.When islet cells from pancreases of organ donors are incubated with valproic acid, a time-dependent and dose-dependent increase of insulin levels is observed.

I did go through phases though; starting on Depakote as a child, my mother saw me gaining weight rapidly and encouraged me to join in organized sport like cross-country running, swim teams, hiking, etc. I also kept losing so much blood I was so close to death, my Blood Count was down to 4 1/2 and I had to have 7 pints of blood given back to me. Studies are reporting significant reductions in diabetes, and the need for diabetic medications, after surgery.

Interestingly, weight gain that isn’t associated with excessive calorie intake in obese persons is frequently explained by abnormal functioning of the sympathetic nervous system.Included below are scientific reports in which the effect of Depakote (divalproex sodium) or valproic acid on body weight was evaluated and/or discussed. They told me "You should not even be talking. Furthermore, a greater number of women attempted to lose or control their body weight through dietary changes than men (22.6% versus 7.1%). I vomited at least 10 times a day for those months....and did not lose weight....even though I had not keept down much food at all.

(2007) also reported weight gain in 35 children with epilepsy following 6 months of valproic acid treatment. I was on Depakote for a seizure disorder for over 10 years. According to Verrotti et al. Other reported side effects include worsening depression or even developing suicidal thoughts. These procedures restrict the amount of food by closing off parts of the stomach with bands. Depakote has numerous potential side effects, such as: Depakote also has a tendency to increase your appetite, which can lead to weight gain. The care of patients undergoing bariatric surgery, before and after surgery, requires specialized expertise and facilities. Free Best How To Lose Weight On Depakote Easy Steps. by reducing the dosage to 500 mg per day. Perhaps decreased CYP2C19 function yields higher plasma concentrations of Depakote and a greater physiologic impact (relative to dose) – ultimately increasing risk of weight gain.Furthermore, someone who exercises regularly with aerobic and strength training may be at lower risk of experiencing weight gain and/or unfavorable changes in body composition during Depakote treatment compared to someone who remains relatively sedentary throughout treatment.In this case, if Depakote stabilizes mood by counteracting mania, you might gain some weight simply because you’re no longer exhibiting physiologic changes associated with mania (that promote weight loss). Depakote Weight Loss. Sorry this is so long, but I never want anyone to go through what I went through. I don't seem to have a huge appatite as some do and I exercise every day.

Evidence suggests that Depakote (divalproex sodium) can cause clinically relevant weight gain (7% increase in body weight from baseline) as a side effect.