On eHealthMe, you can check real-world data from 16 million patients, and personalize the results to your gender and age. Common side effects of Valtrex include headache, nausea, vomiting, abdominal pain, cold symptoms, increased liver enzymes, reduction of white blood cells, diarrhea, rash, joint pain, and dizziness. Dove Medical Press However, AKI was significantly more frequently reported in patients simultaneously taking valacyclovir and an NSAID (19.4%) than in patients simultaneously taking acyclovir and an NSAID (10.5%) (p<0.01). The drug interactions with this specific combination of medications are worth exploring further. Nonsteroidal anti-inflammatory drugs (NSAIDs) are likely to be used concomitantly with acyclovir or valacyclovir in clinical practice, but the study on the safety of such combinations was seldom reported. Because they are reported voluntarily from a population of unknown size, estimates of frequency cannot be made. Because of the pharmacologic nature of these interactions, there is a continuum of risk in that the potential for an ADR is dependent on total drug exposure. BRAND NAME(S): Valtrex. Copyright © 2018 by RxList Inc. RxList does not provide medical advice, diagnosis or treatment. Name must be less than 100 characters For the incidence of laboratory abnormalities see Table 2.In a clinical trial for the suppression of recurrent genital herpes infections, the adverse reactions reported by subjects receiving Valtrex 1 gram once daily (n = 269), Valtrex 500 mg once daily (n = 266), or placebo (n = 134), respectively, included headache (35%, 38%, 34%), nausea (11%, 11%, 8%), abdominal In a clinical trial for the reduction of transmission of genital herpes, the adverse reactions reported by subjects receiving Valtrex 500 mg once daily (n = 743) or placebo once daily (n = 741), respectively, included headache (29%, 26%), nasopharyngitis (16%, 15%), and In 2 clinical trials for the treatment of herpes zoster, the adverse reactions reported by subjects receiving Valtrex 1 gram 3 times daily for 7 to 14 days (n = 967) or placebo (n = 195), respectively, included nausea (15%, 8%), headache (14%, 12%), vomiting (6%, 3%), dizziness (3%, 2%), and abdominal pain (3%, 2%). 2020 Apr;42(2):786-795. doi: 10.1007/s11096-020-00984-8.

Health care providers can be instrumental in educating patients that using OTC NSAIDs at the lowest effective dose for the shortest required duration is vital to balancing efficacy and safety. Primary infection with this virus causes...Cold sores (fever blisters) are caused by the herpes simplex virus (HSV), passed on through contact with infected skin or body...A herpes virus that causes cold sores and fever blisters in and around the mouth. Never use this combination of drugs because of high risk for dangerous interactionPotential for serious interaction; regular monitoring by your doctor required or alternate medication may be neededPotential for significant interaction (monitoring by your doctor is likely required)Copyright © 2020 by RxList Inc. RxList does not provide medical advice, diagnosis or treatment. Answer: Magnesium can decrease the absorption and effectiveness of a number of medications, including several common antibiotics, certain statin drugs, and a drug prescribed for atrial fibrillation. The study is created by eHealthMe based on reports of 2,915 people who take Valtrex and Aspirin from the FDA, and is updated regularly. Sixty-five of these pediatric subjects, aged 12 to less than 18 years, received oral tablets for 1 to 2 days for treatment of In clinical trials for the treatment of cold sores, the adverse reactions reported by adolescent subjects receiving Valtrex 2 grams twice daily for 1 day, or Valtrex 2 grams twice daily for 1 day followed by 1 gram twice daily for 1 day (n = 65, across both dosing groups), or placebo (n = 30), respectively, included headache (17%, 3%) and nausea (8%, 0%).Adverse events reported in more than 1 subject across the 3 pharmacokinetic and safety trials in children aged 1 month to less than 12 years were In addition to adverse events reported from clinical trials, the following events have been identified during postmarketing use of Valtrex. Data sources include IBM Watson Micromedex (updated 2 Sep 2020), Cerner Multum™ (updated 1 Sep 2020), … The culprit is the varicella-zoster virus. Medication Uses | How To Use | Side Effects | Precautions | Drug Interactions | Overdose | Notes | Missed Dose | Storage. The case series from the AERS indicated that compared with acyclovir, valacyclovir is more likely to be affected by NSAIDs, and the concomitant use of valacyclovir with some NSAIDs might be associated with increased risk of AKI.