Ten patients [37.2 +/- 11.3 years of age, five women, baseline Clinical Global Impressions (CGI) scale score 4.4 +/- 1.1], seven of whom had not remitted following treatment with bupropion (330 +/- 67 mg, 20.5 +/- 12.2 weeks), and three of whom had not remitted following treatment with duloxetine (90 +/- 30 mg, 18 +/- 2 weeks) received at least 4 weeks of combination treatment. The CGI was administered when the combination was first prescribed, and following 8.8 +/- 4.0 (range, 4-16) weeks of treatment. What to expect. The mean maximum adjunctive duloxetine and bupropion doses were 60.0 +/- 17.3 mg and 175.0 +/- 114.5 mg, respectively. 2008 Jun;22(4):417-25. doi: 10.1177/0269881108091588.PLoS One. That side effect went away as well and eventually I noticed I stopped having cramps and diarrhea. While these reviews might be helpful, they are not a substitute for the expertise, knowledge and judgement of healthcare practitioners.Compare all 15 medications used in the treatment of This article reviews the pharmacologic profile and seminal clinical trials associated with the FDA indication of duloxetine for GAD. Getting off the last 20mg lead to a suicide attempt. eCollection 2014 Sep 11.Liu S, Zha C, Nacro K, Hu M, Cui W, Yang YL, Bhatt U, Sambandam A, Isherwood M, Yet L, Herr MT, Ebeltoft S, Hassler C, Fleming L, Pechulis AD, Payen-Fornicola A, Holman N, Milanowski D, Cotterill I, Mozhaev V, Khmelnitsky Y, Guzzo PR, Sargent BJ, Molino BF, Olson R, King D, Lelas S, Li YW, Johnson K, Molski T, Orie A, Ng A, Haskell R, Clarke W, Bertekap R, O'Connell J, Lodge N, Sinz M, Adams S, Zaczek R, Macor JE.ACS Med Chem Lett. 2. Most of the proplr having bad side effects on here all say they were taking other medications before. Unable to load your delegates due to an error The horror stories on here are not true to my experience.” Name must be less than 100 characters By shannon48514 Last reply 10 months ago. I am slowly reducing by taking 20 MG every other day for 2- weeks, then 20 MG every third day.

Duloxetine Awareness Just About Killed Me . I wonder if that plays a part. “I've been on duloxetine for about 3 months now. It is especially good for nerve pain, such as burning, shooting or stabbing pain, and for pain that keeps you awake at night. Clipboard, Search History, and several other advanced features are temporarily unavailable. Duloxetine belongs to the group of medicines called Serotonin Noradrenergic Reuptake Inhibitors (SNRI) that are also used to treat depression. Duloxetine, a serotonin norepinephrine reuptake inhibitor (SNRI), received Food and Drug Administration (FDA) approval for the treatment of GAD in 2007. Side effects reported during combination treatment were nausea (n = 2), dry mouth (n = 2), jitteriness/agitation (n = 2), fatigue/drowsiness (n = 2), increased blood pressure (n = 1), increased sweating (n = 1), insomnia (n = 1), pruritus (n = 1), headache (n = 1), sexual dysfunction (n = 1), and weight gain (n = 1). By lisa_1616 Last reply 2 years ago. Online evaluation and ongoing check-ins. I am taking it for depression/ panic disorder. I do take Errin birth control, vitamin d3, Multi Vitamin, Duloxetine 30 mg 1 day.

Not a fun ride.. :(” There was a significant decrease in CGI-S (Severity) scores (4.4 +/- 1.1 to 2.1+/-0.9, P <.0001) following combination treatment. I have recently started the transition to stop taking the Duloxetine. Epub 2007 Apr 27.Hudson JI, Wohlreich MM, Kajdasz DK, Mallinckrodt CH, Watkin JG, Martynov OV.Hum Psychopharmacol. “I can't believe this med duloxetine is being prescribed for bipolar disorder. I had never had anxiety before, and I was 65. My side effects are feeling sleepy and tired as well, weird dreams, nausea, sex problems. 1 month ago I started on 30 mg twice a day along with bupropion which I've been using before this, I couldn't have done any of my daily plans I constantly liked to just throw myself in bed and do nothing, it's like a hollow deep and dark pit, it is calm but a dangerous kind of calmness.