As such, little data is available to guide dosage recommendations.It is not necessary to adjust the dosage for people under 75 years of age. This followed a study that found that a single 32-milligram dose might affect the heart's rhythm, leading to QT interval prolongation. The 4-mg dose is taken again 4 and 8 hours after the first dose. Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. There are no research studies supporting that it works in this situation as all of the studies have been done in an emergency room setting. She is as an assistant professor at the Donald and Barbara Zucker School of Medicine at Hofstra/Northwell.How Parents Can Keep Their Kids Hydrated From Vomiting and DiarrheaWhat Parents Should Know About Treating Kids With ZithromaxCommon and Serious Antibiotic Side Effects in ChildrenIf Your Child Vomits Frequently, She May Have Cyclic Vomiting SyndromeA List of Early Flu Symptoms to Watch out for in Children It is ineffective for treating vomiting caused by motion sickness. Even if your child isn't vomiting, if he is too sleepy to drink when he has a stomach virus, then he or she will likely still become dehydrated. Ondansetron was patented in 1984 and approved for medical use in 1990.Although an effective antiemetic agent, the high cost of brand-name ondansetron initially limited its use to controlling A number of medications including ondansetron appear to be effective in controlling postoperative nausea and vomiting. Children 4 to 11 years of age—At first, 4 mg taken 30 minutes before starting cancer treatment.

Sign up for our Health Tip of the Day newsletter, and receive daily tips that will help you live your healthiest life.Charbit B, Alvarez JC, Dasque E, Abe E, Démolis JL, Funck-brentano C. It is also used to prevent and treat the nausea and vomiting that occurs after surgery. The use of ondansetron has not been studied in people older than 75 years of age, and it is not known if dosage should be adjusted for this group.The maximum recommended dose for people with severe liver function impairment is 8 mg/day. If further research supports it, maybe doctors will use it more for kids with the stomach flu. Initially 16 mg, immediately before treatment (over at least 15 minutes), followed by (by intramuscular injection or by slow intravenous injection) 8 mg every 4 hours if required for 2 doses, then (by mouth) 8 mg every 12 hours for up to 5 days, alternatively (by rectum) 16 mg daily for up to 5 days. An antidote to ondansetron is not known.Ondansetron is a highly specific and selective serotonin 5-HTOndansetron (marketed under the brand name Zofran) was developed in the mid-1980s by In addition, the authors found the covert duplication of reports on ondansetron was not easy to detect, because of lack of cross-referencing between papers, and reports containing duplicate findings were cited in eight reviews of the drug.It can be given by mouth, as a tablet or orally disintegrating tablet, or by Early studies have also examined ondansetron as a possible treatment for psychosis resulting from advanced There is tentative evidence that it may be useful in decreasing the desired effects of alcohol.Two small, placebo-controlled trials have been conducted to assess the efficacy of ondansetron for InChI=1S/C18H19N3O/c1-12-19-9-10-21(12)11-13-7-8-16-17(18(13)22)14-5-3-4-6-15(14)20(16)2/h3-6,9-10,13H,7-8,11H2,1-2H3US Food and Drug Administration. This will be dependant upon the emetic potential of chemotherapy administered. The concentration of ondansetron in body tissues as opposed to plasma is also higher than in healthy people.Use of ondansetron has been associated with prolongation of the No specific treatment is available for ondansetron overdose; people are managed with supportive measures. Then, the dose is 4 mg every 8 hours for 1 to 2 days. (2012). If your child was recently in the emergency room because he was (3) ... (Child-Pugh score of 10 or greater), a single maximal daily dose of 8 mg infused over 15 minutes beginning 30 minutes before the start of the emetogenic chemotherapy is recommended. The current practice guidelines, including those from the American Academy of Pediatrics, don't recommend using medications to stop vomiting. Pricing, sizing, legal catgories and other medicinal forms information for ONDANSETRON. Retrieved from IHS. (2006). While many practitioners find Zofran helpful in the emergency room at preventing and treating vomiting from gastroenteritis, your pediatrician might not prescribe it on an outpatient basis.