Knowing about the potential interactions between tamoxifen and antidepressants is crucial if you are considering using any of these drugs. Also, periodically ask if anything has changed regarding the current understanding of potential interactions with your tamoxifen, as this is an area of active research. Ⓒ 2020 About, Inc. (Dotdash) — All rights reservedTamoxifen Can Reduce the Risk of Recurrence by 50 percentTamoxifen Can Reduce the Risk of Recurrence by 50 percentHow Aromatase Inhibitors Prevent Breast Cancer RecurrenceWhat is Ovarian Suppression Therapy and When is it Used?Hot Flashes May Be a Silver Lining of Breast Cancer TreatmentThe Estrogen Drug That Reduces Your Breast Cancer RiskWhat Happens When Breast Cancer Spreads to the BrainBalancing the Benefits of Hormone Therapy With Bone Pain Side EffectsBenefits and Side Effects of Femara (Letrozole) for Breast CancerThe Cost and Effectiveness of Tamoxifen vs. Aromatase InhibitorsIs There a Link Between Caffeine and Breast Cancer?

This report displays the potential drug interactions for the following 2 drugs:Grapefruit and grapefruit juice may interact with ALPRAZolam and lead to potentially dangerous side effects. Unfortunately, many common medicines can block or slow down CYP2D6, and that would make tamoxifen less effective. Select one or more newsletters to continue. In recent years, however, researchers have learned that some antidepressant medications can reduce these symptoms, as well as treat the all-too-common depression that can accompany breast cancer. Meanwhile, some supplements believed to help alleviate depression can interact with tamoxifen as well. The below table summarizes what is known about several antidepressants and supplements thus far.

Do not increase or decrease the amount of grapefruit products in your diet without first talking to your doctor.

Most doctors recommend that patients only take a tablespoon or two each day. We would like to show you a description here but the site won’t allow us. Whether soy products are effective for hot flashes is also uncertain.

Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation.

This, of course, means that your tamoxifen treatment may not work as intended—or, perhaps, at all. Ⓒ 2020 About, Inc. (Dotdash) — All rights reserved By using Verywell Health, you accept our Dilute it with water before drinking it to prevent the acid from harming the enamel of your teeth or your stomach lining. The drug is also used as a preventive agent for women at high risk of developing breast cancer, based on family history or genetic profile. While there are many that are problematic in this regard, there are several options that are believed to be relatively safe. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation. While there are many that are problematic in this regard, there are several options that are believed to be safe. Since many people take tamoxifen for five to 10 years, this is even more important. What this means is that if you should go to urgent care with an infection, for example, talk to your oncologist or pharmacist before taking any medications that have been prescribed during that consultation. Tamoxifen is broken down to endoxifen by the cytochrome P450 enzyme CYP2D6 (plus others that are less important). Interactions between tamoxifen and other drugs are common, and this includes many medications in addition to antidepressants. (For those who are postmenopausal, or who are premenopausal but have received ovarian suppression therapy, an  For tamoxifen to do its job, it needs to be broken down in the body by a key protein known as CYP2D6. This medication can increase the effects of alcohol. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products.

We comply with the HONcode standard for trustworthy health information - The side effects of tamoxifen include menopausal-type symptoms such as hot flashes, low libido, and vaginal dryness. Discuss the use of grapefruit products with your doctor. Endoxifen is 30 to 100 times stronger than tamoxifen and is responsible for most of the clinical effects. These medications may interact and cause very harmful effects.