A preventative placebo-controlled study (the HOPE-study), was carried out in which ramipril was added to standard therapy in more than 9,200 patients. Myocardial ischaemia including angina pectoris or myocardial infarction, tachycardia, arrhythmia, palpitations, oedema peripheral White blood cell count decreased (including neutropenia or agranulocytosis), red blood cell count decreased, haemoglobin decreased, platelet count decreased Bone marrow failure, pancytopenia, haemolytic anaemia Cerebral ischaemia including ischaemic stroke and transient ischaemic attack, psychomotor skills impaired, burning sensation, parosmia Non-productive tickling cough, bronchitis, sinusitis, dyspnoea Bronchospasm including asthma aggravated, nasal congestion Gastrointestinal inflammation, digestive disturbances, abdominal discomfort, dyspepsia, diarrhoea, nausea, vomiting Pancreatitis (cases of fatal outcome have been very exceptionally reported with ACE inhibitors), pancreatic enzymes increased, small bowel angioedema, abdominal pain upper including gastritis, constipation, dry mouth Renal impairment including renal failure acute, urine output increased, worsening of a pre-existing proteinuria, blood urea increased, blood creatinine increased Angioedema; very exceptionally, the airway obstruction resulting from angioedema may have a fatal outcome; pruritus, hyperhidrosis Toxic epidermal necrolysis, Stevens-Johnson syndrome, erythema multiforme, pemphigus, psoriasis aggravated, dermatitis psoriasiform, pemphigoid or lichenoid exanthema or enanthema, alopecia Syndrome of inappropriate antidiuretic hormone secretion (SIADH)Hypotension, orthostatic blood pressure decreased, syncope Anaphylactic or anaphylactoid reactions, antinuclear antibody increased Hepatic enzymes and/or bilirubin conjugated increased, Acute hepatic failure, cholestatic or cytolytic hepatitis (fatal outcome has been very exceptional). The likelihood and severity of anaphylactic and anaphylactoid reactions to insect venom and other allergens are increased under ACE inhibition.
Talk with your doctor if you have concerns about this. This could be a symptom of a condition called intestinal angioedema. The peak effect of a single dose is usually reached 3 to 6 hours after oral administration. Studies involving chronic oral administration have been conducted in rats, dogs and monkeys. This site uses cookies.

Currently available data are described in sections 4.8, 5.1, 5.2, and 5.3 but no recommendation on posology can be made. By continuing to browse the site you are agreeing to our policy on the use of cookies.

≥ 1/100 to < 1/10) in paediatric, and "uncommon" (i.e. Ramipril: 2.5 mg once a day: 5 mg twice a day or 10 mg once a day ‡ * Use the higher dose if there are still symptoms at the lower target dose. When suggestions are available use up and down arrows to review and ENTER to select.
Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes.Mayo Clinic does not endorse companies or products. Advertising revenue supports our not-for-profit mission.Check out these best-sellers and special offers on books and newsletters from Mayo Clinic. As with other ACE inhibitors, ramipril may be less effective in lowering blood pressure in black people than in non black patients, possibly because of a higher prevalence of hypertension with low renin level in the black hypertensive population. Elderly. pms-Ramipril-HCTZ: This combination product contains two active ingredients: ramipril and hydrochlorothiazide.