Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation.These medications may cause some risk when taken together. Available for Android and iOS devices. For example, taking sumatriptan along with certain antidepressants can cause a group of symptoms called serotonin syndrome. Sumatriptan has the following interaction information: St John's wort. Periodic cardiovascular evaluations should be performed during intermittent, long-term use.The group of drugs known as 5-hydroxytryptamine1 receptor (5-HT1) agonists can cause vasospastic reactions, including coronary vasospasm, peripheral vascular ischemia, and colonic ischemia.
There may be a risk of serotonergic syndrome also if sumatriptan is used concomitantly with lithium. In general, patients with potentially unrecognized CAD as predicted by the presence of risk factors (e.g., hypertension, hypercholesterolemia, tobacco use, obesity, diabetes, strong family history of CAD, female with surgical or physiological menopause, or male over 40 years of age) should not be administered 5-HT1 agonists unless a cardiovascular evaluation provides satisfactory clinical evidence indicating the lack of CAD, ischemic heart disease, or other significant underlying cardiovascular disease. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.Things to remember when you fill your prescription.WebMD does not provide medical advice, diagnosis or treatment.

… Both sumatriptan and St John's wort can increase the risk of serotonin syndrome. Significant elevation in blood pressure, including hypertensive crisis, has also been reported on rare occasions in patients with and without a history of hypertension, as have transient increases in blood pressure and peripheral vascular resistance.
An interaction may occur between sumatriptan and MAOIs and concomitant administration is contra-indicated (see section 4.3). How is this medicine (Sumatriptan Injection) best taken? Rarely, serious adverse cardiac events including acute myocardial infarction, arrhythmia, cardiac arrest, and death have been reported within a few hours following the administration of 5-HT1 agonists, in some cases even in patients with no prior history or findings of coronary artery disease (CAD). Rarely, serious adverse cardiac events including acute myocardial infarction, arrhythmia, cardiac arrest, and death have been reported within a few hours following the administration of 5-HT1 agonists, in some cases even in patients with no prior history or findings of coronary artery disease (CAD). Select one or more newsletters to continue. These medications are not usually taken together. All generic drug interactions for sumatriptan oral (lists will include brand and generic names): 8 contraindicated drug interactions; 24 serious drug interactions; 124 significant drug interactions; 12 minor drug interactions; UNABLE TO DISPLAY ANY INTERACTIONS AT THIS TIME. There are many sumatriptan drug interactions to be aware of. Imitrex (sumatriptan) is a headache medicine that narrows blood vessels around the brain.

Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation.Selected from data included with permission and copyrighted by First Databank, Inc. Sumatriptan also reduces substances in the body that can trigger headache pain, nausea, sensitivity to light and sound, and other migraine symptoms.. Imitrex … These medications are not usually taken together. If your child has been given sumatriptan injection, ask the doctor for information about the benefits and risks. The group of drugs known as 5-hydroxytryptamine1 receptor (5-HT1) agonists can cause vasospastic reactions, including coronary vasospasm, peripheral vascular ischemia, and colonic ischemia. In general, patients with potentially unrecognized CAD as predicted by the presence of risk factors (e.g., hypertension, hypercholesterolemia, tobacco use, obesity, diabetes, strong family history of CAD, female with surgical or physiological menopause, or male over 40 years of age) should not be administered 5-HT1 agonists unless a cardiovascular evaluation provides satisfactory clinical evidence indicating the lack of CAD, ischemic heart disease, or other significant underlying cardiovascular disease. A few of these symptoms include confusion, hallucinations, diarrhea, and difficulty walking. An interaction may occur between sumatriptan and MAOIs and concomitant administration is contraindicated (see section 4.3). As a precaution, the manufacturers recommend that the first dose be administered under medical surveillance in such patients, and that electrocardiographic monitoring be considered during the interval immediately following administration to help detect any asymptomatic cardiac ischemia that may occur. Use sumatriptan injection as ordered by your doctor. Severe Interactions. Check Now » Drug Interaction Categories. There have been rare post-marketing reports describing patients with serotonin syndrome (including altered mental status, autonomic instability and neuromuscular abnormalities) following the use of SSRIs and sumatriptan.