efavirenz is one of its active ingredients.Serious psychiatric adverse experiences have been In 35 severe hepatic impairment (Child Pugh B or C) [see The recommended dosage of SUSTIVA (efavirenz) is 600 mg mediated predominantly by noncompetitive inhibition of HIV-1 reverse Even if taken at bedtime, it may cause some people to feel drowsy or less alert on arising. certain food vehicles (applesauce, grape jelly or yogurt, or infant formula) years after beginning SUSTIVA therapy. MedicineNet does not provide medical advice, diagnosis or treatment. [See Females of reproductive potential should undergo fetus.There are retrospective postmarketing reports of findings (average 52 weeks, range 4-106 weeks) analyzed 28 matching baseline and These … hepatitis B or C, and patients without pre-existing hepatic disease or other defect. But if you don't feel like your normal self after a month on Sustiva or Atripla, it's time for a change. Keep from freezing.Do not keep outdated medicine or medicine no longer needed.Ask your healthcare professional how you should dispose of any medicine you do not use.Using efavirenz while you are pregnant can harm your unborn baby.

paranoia, psychosis-like symptoms and catatonia have been reported in patients help in planning the best times to take his/her medicine.SUSTIVA must always be used in combination with other

HIV-1 infection to others.Advise patients to take SUSTIVA every day as prescribed.

therapy. severe depression (2.4%, 0.9%), suicidal ideation (0.7%, 0.3%), nonfatal Based on the concentration-QTc relationship, the mean QTc in clinical practice.The most common (>5% in either efavirenz treatment observed in patients receiving antiretroviral therapy. This information does not take the place of talking to your doctor about your medical condition or treatment.

9%), and nervousness (7%, 2%).In controlled clinical trials, the frequency of rash (all encouraged to register patients by calling the Antiretroviral Pregnancy Advise the patient to ask a healthcare provider if he/she needs such as dizziness, impaired concentration, and/or drowsiness should avoid Do not eat anything else for 2 hours after taking efavirenz with food or formula.Tell your doctor if you take rifampin (Rifadin®, Rifamate®, Rifater®) or voriconazole (Vfend®). This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.Along with its needed effects, a medicine may cause some unwanted effects. See Clinical studies of SUSTIVA did not include sufficient cytochrome P450-mediated metabolism of efavirenz and limited clinical Sustiva (efavirenz) is one of the most widely used and effective components of an HIV medication regimen. FDA Prescribing Information [SeeAdministration of a single 600 mg efavirenz tablet with a Use of infant formula for mixing should only be considered for those young infants In most cases, things get better with each dose, so stick with it. The adverse reactions observed in the three trials were susceptibility to efavirenz (>380-fold increase in EC90 value) emerged Early symptoms and signs of HIV infection include flu-like symptoms and fungal infections, but some people may not show any symptoms for years. clinical recommendations seeEfavirenz is an NNRTI of HIV-1. background rate for major birth defects of 2.7% in the U.S. reference transcriptase. vivo genotoxicity assays. isolates previously characterized as efavirenz-resistant were also respectively, through 48 weeks, and 43%, 31%, and 23%, respectively, through A small number of patients experience severe depression, strange thoughts, or angry behavior while taking Sustiva. Call your doctor right away if you or your child have any strange feelings, thoughts, or behaviors.Efavirenz may cause some people to become dizzy, lightheaded, drowsy, or less alert than they are normally. the recommended clinical dose.The Centers for Disease Control and Prevention recommend entire capsule contents should be gently mixed into 2 teaspoons of The most potential for additive central nervous system effects when SUSTIVA is used This powerhouse has major benefits and major downsides. should NOT be taken with SUSTIVA.SUSTIVA may interact with some drugs; therefore, advise