Triamcinolone acetonide is designated chemically as 9-Fluoro-11β, 16α,17,21-tetrahydroxypregna-1,4-diene- 3,20-dione cyclic 16,17-acetal with acetone. However, the results offer possibilities and warrant further study.Since the completion of this clinical study involving forty-three patients, we have continued the study of a number of patients in which fluid has been removed from the lip vesicle and inoculated upon fertile egg membrane to observe if lesions would occur on the membranes. Topical triamcinolone acetonide is available in different strengths, including 0.005%, 0.025%, 0.1%, and 0.5% solutions. Occlusive Dressing Technique Occlusive dressings may be used for the management of psoriasis or other recalcitrant conditions. Thus, it would seem from this preliminary study that triamcinolone acetonide may prove to be beneficial in the treatment of this most persistent and difficult oral herpetic lesion.This trial did not include enough patients to offer conclusive evidence. Triamcinolone reduces the swelling, itching, and redness that can occur in these types of conditions. Hydrocortisone Topical rated 7.4/10 vs Triamcinolone Topical rated 7.6/10 in overall patient satisfaction. Even though this steroid is readily absorbed through the mucous membranes, eosinophil counts and 17-ketosteroid determinations indicate that there is little alteration in adrenal cortical activity. ScienceDirect ® is a registered trademark of Elsevier B.V.The clinical use of triamcinolone acetonide in the treatment of herpes simplex of the oral mucous membranesScienceDirect ® is a registered trademark of Elsevier B.V. Topical corticosteroids share anti-inflammatory, antipruritic and vasoconstrictive actions. As there are no adequate and well-controlled studies in pregnant women, the risk of birth defects in humans is not known. Triamcinolone acetonide cream and mupirocin cream are topical medications used to treat skin conditions.

None of the patients showed any undesirable effects.In all but two of the cases studied, beneficial effects, as far as pain and healing time were concerned, were noted. A highly active topical agnet, triamcinolone acetonide, which is a comparatively new corticosteroid, has been employed in the treatment of acute and chronic herpetic lesions of the oral mucous membranes and the lips. Patients were examined and evaluated daily to determine any undesirable side reactions. Triamcinolone acetonide cream is used to relieve skin inflammation, itching, dryness, and redness. The structural formula of triamcinolone acetonide is as follows:Each gram of Triamcinolone Acetonide Ointment, USP 0.5% provides 5 mg triamcinolone acetonide in an ointment base of light mineral oil and white petrolatum. Those patients suffering from chronic cycles of the herpetic vesicles complained of pain, itching, and a burning sensation prior to vesicle formation. In nearly every instance the patients demonstrating these signs and symptoms could be successfully treated and the vesicle formation aborted with early use of the triamcinolone acetonide in Orabase. Mupirocin cream is indicated for the treatment of secondarily infected traumatic skin lesions due to susceptible isolates of Staphylococcus aureus and Streptococcus pyogenes. Triamcinolone Acetonide Ointment, USP 0.5% is indicated for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses.Topical corticosteroids are contraindicated in those patients with a history of hypersensitivity to any of the components of the preparations.Systemic absorption of topical corticosteroids has produced reversible hypothalamic-pituitary-adrenal (HPA) axis suppression, manifestations of Cushing’s syndrome, hyperglycemia, and glucosuria in some patients.Patients using topical corticosteroids should receive the following information and instructions:A urinary free cortisol test and ACTH stimulation test may be helpful in evaluating HPA axis suppression.Long-term animal studies have not been performed to evaluate the carcinogenic potential or the effect on fertility of topical corticosteroids. If such lesions do occur, the membranes are harvested and eventually combined with antisera and reinoculated on fertile egg membrane to determine, this time, if there is a failure of lesion formation. It is understood, however, that these tests are of limited value and that one must always consider the consequences in treating those patients in whom corticosteroids are contraindicated.

A number of papers have been published concerned with the contraindications of steroid therapy in cases involving varicella, ocular lesions, poliomyelitis, and other diseases. A doctor may prescribe triamcinolone acetonide ointment to treat skin conditions like eczema and psoriasis. It is not known whether topical administration of corticosteroids could result in sufficient systemic absorption to produce detectable quantities in breast milk.

Systemically administered corticosteroids are secreted into breast milk in quantities not likely to have a deleterious effect on the infant. Apply a thin film of ointment to the lesion, cover with a pliable nonporous film, and seal the edges. Thus, the value of this treatment may be considered with respect to both the preventive possibilities and the treatment possibilities as related to a reduced healing time and a lessening of painful symptoms.Those patients suffering from chronic herpetic lesions continuted to have recurrences, even after treatment.We use cookies to help provide and enhance our service and tailor content and ads. Talk with your child's healthcare provider about the benefits and risks of using triamcinolone acetonide ointment. A link to more details is also provided. By continuing you agree to the Copyright © 2020 Elsevier B.V. or its licensors or contributors.

In the patient in whom there is no contraindication for corticosteroid therapy we have found no side affects or detrimental changes resulting from the use of triamcinolone acetonide for oral mucous membrane and labial herpetic lesions. The potency depends on the strength and the form that you use. Children can use triamcinolone acetonide ointment.