In the 1-year trial, the group receiving ADVAIR DISKUS 500/50 had a significantly lower rate of moderate and severe exacerbations compared with placebo (25.4% reduction compared with placebo [95% CI: 13.5, 35.7]) but not when compared with its components (7.5% reduction compared with fluticasone propionate [95% CI: -7.3, 20.3] and 7% reduction compared with salmeterol [95% CI: -8.0, 19.9]). Other adverse reactions not previously listed, whether considered drug-related or not by the investigators, that were reported more frequently by subjects with COPD treated with ADVAIR DISKUS compared with subjects treated with placebo include the following: syncope; ear, nose, and throat infections; ear signs and symptoms; laryngitis; nasal congestion/blockage; nasal sinus disorders; pharyngitis/throat infection; hypothyroidism; dry eyes; eye infections; gastrointestinal signs and symptoms; oral lesions; abnormal liver function tests; bacterial infections; edema and swelling; viral infections.There were no clinically relevant changes in these trials. To reduce exacerbations of COPD in patients with a history of exacerbations. Four (4) large, 26-week, randomized, double-blind, active-controlled clinical safety trials were conducted to evaluate the risk of serious asthma-related events when LABA were used in fixed-dose combination with ICS compared with ICS alone in subjects with asthma. Follow your doctor's instructions on how you should take your medicine.This medicine should not be used if you are having a severe COPD attack, or if symptoms of a COPD attack has already started. The 3 adult and adolescent trials were designed to rule out a risk margin of 2.0, and the pediatric trial was designed to rule out a risk margin of 2.7. May 6, 2020 Ophthalmic examinations were conducted at baseline and at 48, 108, and 158 weeks. In vitro studies show salmeterol to be at least 50 times more selective for beta The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.Using this medicine with any of the following medicines is not recommended. The strip contains a combination of fluticasone propionate 100, 250, or 500 mcg and salmeterol 50 mcg per blister.The use of ADVAIR DISKUS is contraindicated in the following conditions:Use of LABA as monotherapy (without ICS) for asthma is associated with an increased risk of asthma-related death The findings of this trial, along with extrapolation of efficacy data from subjects aged 12 years and older, support the overall conclusion that ADVAIR DISKUS 100/50 is efficacious in the treatment of asthma in subjects aged 4 to 11 years.Trial 4 enrolled subjects with moderate to severe persistent asthma with a history of asthma-related hospitalization or at least 1 asthma exacerbation in the previous year treated with systemic corticosteroids. Advise patients to treat acute symptoms with an inhaled, short-acting beta The initiation of ADVAIR DISKUS in this setting is not appropriate.Serious acute respiratory events, including fatalities, have been reported when salmeterol, a component of ADVAIR DISKUS, has been initiated in patients with significantly worsening or acutely deteriorating asthma. Although the clinical significance of these effects is not known, caution is advised in the coadministration of ADVAIR DISKUS with non–potassium-sparing diuretics.There are insufficient data on the use of ADVAIR DISKUS or individual monoproducts, fluticasone propionate and salmeterol xinafoate, in pregnant women.

However, do not swallow the water after rinsing.The dose of this medicine will be different for different patients.

Your doctor may want you or your child to have your eyes checked by an ophthalmologist (eye doctor).This medicine may decrease bone mineral density when used for a long time. Online Pharmacy – Best Cheapest Drugs. Drug information provided by: IBM Micromedex. ADVAIR DISKUS should be used for patients not adequately controlled on a long-term asthma control medication such as an inhaled corticosteroid (ICS) or whose disease warrants initiation of treatment with both an ICS and long-acting beta Do not poke holes in the canister or throw it into a fire, even if the canister is empty.Keep the medicine in the foil pouch until you are ready to use it. ADVAIR DISKUS is indicated for the twice-daily treatment of asthma in patients aged 4 years and older.