Your hearing will be checked prior to you receiving cisplatin and as needed throughout treatment.
Cisplatin Vial Side Effects by Likelihood and Severity COMMON side effects.
Even if your menstrual cycle stops or you believe you are not producing sperm, you could still be fertile and conceive. There are a number of things you can do to manage the side effects of cisplatin. While receiving treatment, your Talk to your oncology care team so they can prescribe medications to help you manage Call your oncology care team if you are unable to keep fluids down for more than 12 hours or if you feel lightheaded or dizzy at any time.Cisplatin can cause hearing loss and ringing in the ears.
The nurse or doctor who gives cisplatin must be carefully trained. If experienced, these tend to have a Severe expressionIf experienced, these tend to have a Less Severe expressionIf experienced, these tend to have a Severe expressionIf experienced, these tend to have a Less Severe expressionIf experienced, these tend to have a Severe expressionIf experienced, these tend to have a Less Severe expressionSelected from data included with permission and copyrighted by First Databank, Inc. Cisplatin may cause serious kidney problems. All rights reserved. Possible Side Effects. Effective birth control is necessary during treatment. Cisplatin is a chemotherapy drug used to treat testicular, ovarian, bladder, head and neck, lung and cervical cancer.It may also be used to treat other cancers.
How Cisplatin Is Given Cisplatin is administered through a vein (intravenously or IV) as an infusion.
Numerous studies have demonstrated that several mechanisms, including oxidative stress, DNA damage, and inflammatory responses, are closely associated with cisplatin-induced nephrotoxicity If cisplatin escapes from the vein it can cause tissue damage. Talk to your care team about these recommendations. They can help you decide what will work best for you. It can be given alone or with other drugs.Even when carefully and correctly administered by trained personnel, this drug may cause a feeling of burning and pain. Notify your healthcare provider if you notice decreased urine output, blood in the urine, swelling in the ankles, or loss of appetite.Your red blood cells are responsible for carrying oxygen to the tissues in your body. 3-deazaneplanocin A (3-DZNeP) has been used as an inhibitor of enhancer of zeste homolog 2 (EZH2). There is a risk that this medication may leak out of the vein at the injection site, resulting in tissue damage that can be severe.
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Each person reacts differently to medicines, so your child will not necessarily suffer from every side effect mentioned. By preventing them from dividing, the medication can stop the cancer from growing.Cisplatin is given through intravenous (IV, into a vein) infusion. All content © 2020 Trustees of the University of Pennsylvania. All of these compounds are vital for cells to divide and grow. You will be given intravenous fluids prior to receiving cisplatin. The use of cisplatin in patients with pre-existing kidney dysfunction and the renal effects of the platinum analogs, carboplatin and oxaliplatin, are discussed elsewhere. Nephrotoxicity is the most well-known and clinically important toxicity. Depending on the severity of your reaction, you may still be able to receive the medication with a pre-medication to prevent a reaction, or if the medication is given at a slower rate.Exposure of an unborn child to this medication could cause birth defects, so you should not become pregnant or father a child while on this medication. Discover information about different types of cancerLearn about cancer, diagnosis, treatment, coping & survivorshipFind resources & tools for oncology healthcare professionalsCisplatin is a heavy metal compound that inhibits synthesis of RNA, DNA, and protein in cells. You should not breastfeed while receiving this medication.Receive the latest resources and updates in your inbox. These are some of the most common or important side effects: Kidney Problems
If the area of injection becomes red, swollen, or painful at anytime This medication can affect the blood levels certain anti-seizure medications. Tell you doctor right away if you have blood in urine, change in frequency of urination or amount of urine, difficulty in breathing, drowsiness, increased thirst, loss of appetite, nausea or vomiting, swelling of the feet or lower legs, or weakness. These are some of the most common or important side effects:This medication can cause kidney problems, including an increased creatinine level, which your oncology care team will monitor for using blood tests.