J Clin Psychopharmacol 26 (2006): 681-68311. "No Effect of Pyridoxine on the Incidence of Myelosuppression during Prolonged Linezolid Treatment." This drug was discontinued and the Bell's palsy completely resolved by day 90. Narita M, Tsuji BT, Yu VL "Linezolid-associated peripheral and optic neuropathy, lactic acidosis, and serotonin syndrome."

"Hematologic Effects of Linezolid: Summary of Clinical Experience." "The role of vitamin B6 in the prevention of haematological toxic effects of linezolid in patients with cancer." This drug was stopped within 4 days of identifying lactic acidosis. Jodlowski TZ, Melnychuk I, Conry J "Linezolid for the treatment of Nocardia spp. John CC, Schreiber JR "Therapies and Vaccines for Emerging Bacterial Infections: Learning from Methicillin-resistant Staphylococcus aureus." Available for Android and iOS devices.We comply with the HONcode standard for trustworthy health information - Falagas ME, Manta KG, Ntziora F, Vardakas KZ "Linezolid for the treatment of patients with endocarditis: a systematic review of the published evidence." Faguer S, Kamar N, Fillola G, Guitard J, Rostaing L "Linezolid-related pancytopenia in organ-transplant patients: report of two cases." Clin Infect Dis 42 (2006): 1500; author reply 150148.

Clin Infect Dis 38 (2004): 767-820. Pharmacotherapy 23 (2003): 682-528. Certain illegal drugs and dietary supplements also are associated with serotonin syndrome.Serotonin is a chemical your body produces that's needed for your nerve cells and brain to function. N Engl J Med 348 (2003): 86-760.

Clin Infect Dis 41 Suppl 5 (2005): S293-3029. Clin Infect Dis 42 (2006): 66-7250. Joshi L, Taylor SR, Large O, Yacoub S, Lightman S "A case of optic neuropathy after short-term linezolid use in a patient with acute lymphocytic leukemia." Clin Infect Dis 42 (2006): 435-6; author reply 437-859. Halpern M "Linezolid-induced pancytopenia." The time from the onset of therapy to the first sign of optic neuropathy averaged 10 months (range: 1 to 48 months) in 6 patients with only optic neuropathy. Pharmacotherapy 21 (2001): 1010-358. The patient had no remaining symptoms 4 months after his second episode.Convulsions have also been reported during postmarketing experience.In cases with known outcome, tooth discoloration was removable with professional dental cleaning (manual descaling).A 60-year-old man with spondylodiscitis developed a fatal case of C difficile Superficial tooth discoloration and tongue discoloration have also been reported during postmarketing experience.Thrombocytopenia (platelets less than 100,000/mm3) has been reported in 32% of patients (n=19) using this drug for more than 10 days.

Shneker BF, Baylin PD, Nakhla ME "Linezolid inducing complex partial status epilepticus in a patient with epilepsy." Am J Med 121 (2008): e130. Although toxicity from coadministration of linezolid and serotonergic agents is not reported in phase I, II, or III trials, 2 multiple case reports describe temporally related linezolid administration and serotonin toxicity manifesting as serotonin syndrome. Cerner Multum, Inc. "Australian Product Information." Clin Infect Dis 43 (2006): e89-e915. Clin Infect Dis 49 (2009): 645-6; author reply 64664. J Antimicrob Chemother 58 (2006): 273-8031. Pharmacotherapy 27 (2007): 1189-9725. You may report them to the The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. For example, irreversible sensory loss and peripheral neuropathy were reported in a patient after using this drug for 6 months for actinomycosis. The most common side effects leading to discontinuation were diarrhea, headache, nausea, and vomiting.Several cases of peripheral and/or optic neuropathy have been reported, mainly when the duration of therapy was longer than 28 days. Clin Infect Dis 37 (2003): 1609-1656.

Infection 35 (2007): 275-743.

Grau S, Morales-Molina JA, Mateu-de Antonio J, Marin-Casino M, Alvarez-Lerma F "Linezolid: low pre-treatment platelet values could increase the risk of thrombocytopenia." Two of the 7 patients died despite stopping therapy.

Senneville E, Legout L, Valette M, et al. Serotonin syndrome occurs when you take medications that cause high levels of the chemical serotonin to accumulate in your body.Serotonin syndrome can occur when you increase the dose of such a drug or add a new drug to your regimen. Wiener M, Guo Y, Patel G, Fries BC "Lactic Acidosis after Treatment with Linezolid." Lee E, Burger S, Shah J, et al.

Clin Infect Dis 46 (2008): 264-57. More frequently reported side effects include:anemia, decreased hemoglobin, and thrombocytopenia.

Clin Infect Dis 48 (2009): e73-4Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.Some side effects may not be reported.

Ann Pharmacother 43 (2009): 172861. Ferry T, Ponceau B, Simon M, et al. Thai XC, Bruno-Murtha LA "Bell's Palsy Associated with Linezolid Therapy: Case Report and Review of Neuropathic Adverse Events." Strawn JR, Keck PE Jr, Caroff SN "Neuroleptic malignant syndrome." J Antimicrob Chemother 60 (2007): 1361-933.

This study concluded vitamin B6 was not beneficial in the prevention of leukopenia or thrombocytopenia, but found a possible trend towards the prevention of anemia.At least 7 instances of lactic acidosis have been reported after use of this drug.

Clin Infect Dis 35 (2002): 347-840. "Linezolid-associated toxic optic neuropathy: a report of 2 cases." Linezolid is generally well-tolerated, with some minor side-effects like gastrointestinal disturbances, headache, and rashes. Refaat M, Hyle E, Malhotra R, Seidman D, Dey B "Linezolid-Induced Lingua Villosa Nigra." Clin Infect Dis 42 (2006): 1813-4; author reply 1814-541. Pharmacotherapy 26 (2006): 1183-917.

Frippiat F, Bergiers C, Michel C, Dujardin JP, Derue G "Severe bilateral optic neuritis associated with prolonged linezolid therapy."