Some side effects of rilpivirine can be serious. Many side effects from HIV medicines, such as nausea or occasional dizziness, are manageable. See the AIDS info fact sheet on HIV Medicines and Side Effects for more information. Other side effects include:vulvovaginal candidiasis, diarrhea, dizziness, dysphagia, epigastric discomfort, melanoglossia, nausea and vomiting, sore throat, stomatitis, and anorexia.
Although not all of these side effects may occur, if they do occur they may need medical attention.Some side effects of rilpivirine may occur that usually Check with your health care professional if any of the following side effects Most side effects occurred in the first 48 weeks of therapy. Headache. This drug was discontinued due to side effects in 2% of patients. In subjects with mild or moderate baseline renal dysfunction, the serum creatinine increase observed was similar to that seen in subjects with normal renal function. Depression. Commonly reported side effects of minocycline include: headache. Serious side effects of rilpivirine include severe rash, depression, mood changes, and liver problems. The most common side effects (at least moderate severity) were depression, headache, insomnia, increased transaminases, and rash. COMMON side effects. Difficulty Sleeping. In the phase 3 clinical trials, ten patients (1%), discontinued this drug due to psychiatric disorders.During phase 3 trials through 96 weeks, depressive disorders (regardless of causality, severity) were reported in 9% of patients.Grade 1, 2, and 3 increases in creatinine have been reported in 6%, 1%, and less than 1% of patients, respectively.During phase 3 trials, an increase in serum creatinine was seen over 96 weeks of therapy.
Tooth Discoloration If experienced, these tend to have a Less Severe expression 1. "Week 96 efficacy and safety of rilpivirine in treatment-naive, HIV-1 patients in two Phase III randomised trials." J Antimicrob Chemother (2012):4. "Product Information. O 03. See below for a comprehensive list of adverse effects. If experienced, these tend to have a Less Severe expression. Throwing Up A Skin Rash. Tibotec Pharmaceuticals, Titusville, NJ. Common side effects of Minocin include: nausea, vomiting, upset stomach, diarrhea, lightheadedness, These changes were not considered clinically relevant and no subject discontinued therapy due to increases in serum creatinine.In the pooled phase 3 trials, at week 96, there was an overall mean change from baseline in basal cortisol of -19.1 nmol/L (-0.69 mcg/dL) in the rilpivirine group, and of -0.6 nmol/L (-0.02 mcg/dL) in the In the rilpivirine group, 43 of 588 patients with normal 250 mcg ACTH stimulation test at baseline developed abnormal 250 mcg ACTH stimulation test (peak cortisol level less than 18.1 mcg/dL) during the trial versus 18 of 561 patients in the efavirenz group.
Head Pain 3. Minocin Capsules (minocycline hydrochloride) is a tetracycline antibiotic used to treat many different bacterial infections, such as urinary tract infections, severe acne, gonorrhea, tick fever, chlamydia, and others. Treatment was discontinued due to side effects, regardless of severity, in 2% of patients taking rilpivirine in combination with emtricitabine-tenofovir DF. If experienced, these tend to have a Severe expression 1. O 0Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.Some side effects may not be reported. Cerner Multum, Inc. "Australian Product Information." Abnormal 250 mcg ACTH stimulation test at week 96 was seen in 14 of the 43 rilpivirine patients and 9 of the 18 efavirenz patients. Clinical significance of abnormal 250 mcg ACTH stimulation tests (or the higher rate in the rilpivirine group) has not been established.Overall, there were no serious side effects, deaths, or treatment discontinuations that could clearly be attributed to adrenal insufficiency.1. Itching 4.