0000015642 00000 n
Aminophylline Tablet. In general, patients who experience an acute overdose are less likely to experience seizures than patients who have experienced a chronic overdosage, unless the peak serum theophylline concentration is >100 mcg/mL. Aminophylline pet meds are primarily bronchodilators, but they can also be used to treat heart failure in certain cases. 16515 Oranienburg. Dear patient, Please read the following instructions carefully. Elderly patients also appear to be more sensitive to the toxic effects of theophylline after chronic overdosage than younger patients. Theophylline clearance has been shown to increase by approximately 50% in young adult tobacco smokers and by approximately 80% in elderly tobacco smokers compared to non-smoking subjects. Dèanadair a antibiotics / solaraiche, Antiparasitic Dhrogaichean, etc.Airson ceistean mu dheidhinn ar bathar no pricelist, cuir post-d agad fhàgail dhuinn agus bidh sinn ann an conaltradh taobh a-staigh 24 uairean a thìde. Theophylline is structurally classified as a methyxanthine. 0000000915 00000 n New interactions are continuously being reported for theophylline, especially with new chemical entities.Most serum theophylline assays in clinical use are immunoassays which are specific for theophylline. Betriebsstätte Oranienburg . Due to the wide intersubject variability of the rate of theophylline metabolism, non-linearity of elimination may begin in some patients at serum theophylline concentrations < 10 mcg/mL. Discontinuation of a concomitant drug that increases theophylline clearance will result in accumulation of theophylline to potentially toxic levels, unless the theophylline dose is appropriately reduced. If only total serum theophylline concentration is measured, this may lead to an unnecessary and potentially dangerous dose increase. Each table contains: Aminophylline BP 100mg. Aminophylline RENAUDIN 250 mg/10 ml : informations générales.
In such cases, the patient may show signs of toxicity at total (bound + unbound) serum concentrations of theophylline in the therapeutic range (10-20 mcg/mL) due to elevated concentrations of the pharmacologically active unbound drug. 0000003904 00000 n Treats COPD, pulmonary edema, asthma, and other lung disorders ; …
Children with rapid rates of theophylline clearance (i.e., those who require a dose that is substantially larger than average [e.g., >22 mg/kg/day] to achieve a therapeutic peak serum theophylline concentration when afebrile) may be at greater risk of toxic effects from decreased clearance during sustained fever.Careful attention to dose reduction and frequent monitoring of serum theophylline concentrations are required in patients with sustained fever (see Other factors associated with decreased theophylline clearance include the third trimester of pregnancy, sepsis with multiple organ failure, and hypothyroidism. Après injection intraveineuse, la théophylline est immédiatement libérée dans l'organisme par hydrolyse. The potency of each compounded capsule is verified through weight and yield checks before it is dispensed. Theophylline does not undergo any appreciable pre-systemic elimination, distributes freely into fat-free tissues and is extensively metabolized in the liver.The pharmacokinetics of theophylline vary widely among similar patients and cannot be predicted by age, sex, body weight or other demographic characteristics. Demethylation to 1-methylxanthine appears to be catalyzed either by cytochrome P-450 1A2 or a closely related cytochrome. Aminophyllim (100mg) - 1000 Tablet (Aminophylline) drug information. After a single dose of 5 mg/kg in adults, a mean peak serum concentration of about 10 mcg/mL (range 5-15 mcg/mL) can be expected 1-2 hr after the dose. After a chronic overdosage, generalized seizures, life-threatening cardiac arrhythmias, and death may occur at serum theophylline concentrations >30 mcg/mL. The following information includes only the average doses of this medicine. Careful attention to dose reduction and frequent monitoring of serum theophylline concentrations are required in patients with CHF (see Tobacco and marijuana smoking appears to increase the clearance of theophylline by induction of metabolic pathways. ╖ Patients with more rapid metabolism, clinically identified by higher than average dose requirements, should receive a smaller dose more frequently to prevent breakthrough symptoms resulting from low trough concentrations before the next dose. * Clearance represents the volume of blood completely cleared of theophylline by the liver in one minute. Dear patient, Please read the following instructions carefully. Information about AMINOPHYLLINE . Values listed were generally determined at serum theophylline concentrations <20 mcg/mL; clearance may decrease and half-life may increase at higher serum concentrations due to non-linear pharmacokinetics.++ Reported range or estimated range (mean ± 2 SD) where actual range not reported.+ NR = not reported or not reported in a comparable format.Theophylline is rapidly and completely absorbed after oral administration in solution or immediate-release solid oral dosage form. The extent of reduction in theophylline clearance in patients with CHF appears to be directly correlated to the severity of the cardiac disease. Children (1-15 years) and adults (16-60 years) without risk factors for impaired clearance.Patients With Risk Factors For Impaired Clearance, The Elderly (>60 Years), And Those In Whom It Is Not Feasible To Monitor Serum Theophylline Concentrations:We comply with the HONcode standard for trustworthy health information - * These data are derived from two studies in patients with serum theophylline concentrations >30 mcg/mL.
Aminophylline Tablet. In general, patients who experience an acute overdose are less likely to experience seizures than patients who have experienced a chronic overdosage, unless the peak serum theophylline concentration is >100 mcg/mL. Aminophylline pet meds are primarily bronchodilators, but they can also be used to treat heart failure in certain cases. 16515 Oranienburg. Dear patient, Please read the following instructions carefully. Elderly patients also appear to be more sensitive to the toxic effects of theophylline after chronic overdosage than younger patients. Theophylline clearance has been shown to increase by approximately 50% in young adult tobacco smokers and by approximately 80% in elderly tobacco smokers compared to non-smoking subjects. Dèanadair a antibiotics / solaraiche, Antiparasitic Dhrogaichean, etc.Airson ceistean mu dheidhinn ar bathar no pricelist, cuir post-d agad fhàgail dhuinn agus bidh sinn ann an conaltradh taobh a-staigh 24 uairean a thìde. Theophylline is structurally classified as a methyxanthine. 0000000915 00000 n New interactions are continuously being reported for theophylline, especially with new chemical entities.Most serum theophylline assays in clinical use are immunoassays which are specific for theophylline. Betriebsstätte Oranienburg . Due to the wide intersubject variability of the rate of theophylline metabolism, non-linearity of elimination may begin in some patients at serum theophylline concentrations < 10 mcg/mL. Discontinuation of a concomitant drug that increases theophylline clearance will result in accumulation of theophylline to potentially toxic levels, unless the theophylline dose is appropriately reduced. If only total serum theophylline concentration is measured, this may lead to an unnecessary and potentially dangerous dose increase. Each table contains: Aminophylline BP 100mg. Aminophylline RENAUDIN 250 mg/10 ml : informations générales.
In such cases, the patient may show signs of toxicity at total (bound + unbound) serum concentrations of theophylline in the therapeutic range (10-20 mcg/mL) due to elevated concentrations of the pharmacologically active unbound drug. 0000003904 00000 n Treats COPD, pulmonary edema, asthma, and other lung disorders ; …
Children with rapid rates of theophylline clearance (i.e., those who require a dose that is substantially larger than average [e.g., >22 mg/kg/day] to achieve a therapeutic peak serum theophylline concentration when afebrile) may be at greater risk of toxic effects from decreased clearance during sustained fever.Careful attention to dose reduction and frequent monitoring of serum theophylline concentrations are required in patients with sustained fever (see Other factors associated with decreased theophylline clearance include the third trimester of pregnancy, sepsis with multiple organ failure, and hypothyroidism. Après injection intraveineuse, la théophylline est immédiatement libérée dans l'organisme par hydrolyse. The potency of each compounded capsule is verified through weight and yield checks before it is dispensed. Theophylline does not undergo any appreciable pre-systemic elimination, distributes freely into fat-free tissues and is extensively metabolized in the liver.The pharmacokinetics of theophylline vary widely among similar patients and cannot be predicted by age, sex, body weight or other demographic characteristics. Demethylation to 1-methylxanthine appears to be catalyzed either by cytochrome P-450 1A2 or a closely related cytochrome. Aminophyllim (100mg) - 1000 Tablet (Aminophylline) drug information. After a single dose of 5 mg/kg in adults, a mean peak serum concentration of about 10 mcg/mL (range 5-15 mcg/mL) can be expected 1-2 hr after the dose. After a chronic overdosage, generalized seizures, life-threatening cardiac arrhythmias, and death may occur at serum theophylline concentrations >30 mcg/mL. The following information includes only the average doses of this medicine. Careful attention to dose reduction and frequent monitoring of serum theophylline concentrations are required in patients with CHF (see Tobacco and marijuana smoking appears to increase the clearance of theophylline by induction of metabolic pathways. ╖ Patients with more rapid metabolism, clinically identified by higher than average dose requirements, should receive a smaller dose more frequently to prevent breakthrough symptoms resulting from low trough concentrations before the next dose. * Clearance represents the volume of blood completely cleared of theophylline by the liver in one minute. Dear patient, Please read the following instructions carefully. Information about AMINOPHYLLINE . Values listed were generally determined at serum theophylline concentrations <20 mcg/mL; clearance may decrease and half-life may increase at higher serum concentrations due to non-linear pharmacokinetics.++ Reported range or estimated range (mean ± 2 SD) where actual range not reported.+ NR = not reported or not reported in a comparable format.Theophylline is rapidly and completely absorbed after oral administration in solution or immediate-release solid oral dosage form. The extent of reduction in theophylline clearance in patients with CHF appears to be directly correlated to the severity of the cardiac disease. Children (1-15 years) and adults (16-60 years) without risk factors for impaired clearance.Patients With Risk Factors For Impaired Clearance, The Elderly (>60 Years), And Those In Whom It Is Not Feasible To Monitor Serum Theophylline Concentrations:We comply with the HONcode standard for trustworthy health information - * These data are derived from two studies in patients with serum theophylline concentrations >30 mcg/mL.