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This product is not recommended for use in immunocompromised patients.Treatment should be initiated as soon as possible after the start of the infection, ideally during the prodromal period or when the lesions first appear.A thin film of cream should be applied to the infected and immediately adjacent skin areas 5 times daily at 4 hour intervals during the day omitting the night time application.Treatment should be continued for 5 days, followed by a further 5 days treatment if healing has not occurred.Patients should wash their hands before and after applying the cream, and avoid unnecessary rubbing of the lesion or touching them with a towel, to avoid aggravating or transferring the infection.Hypersensitivity to aciclovir, valaciclovir, propylene glycol or any other ingredients of the preparation listed in Section 6.1.In severely immunocompromised patients (e.g. 35.000 per tube 5 gram. The tubes are packed individually into cardboard boxes together with package leaflets.42-46 Booth Drive, Park Farm South, Wellingborough, Northamptonshire, NN8 6GTTo bookmark a medicine you must sign up and log in.To view the changes to a medicine you must sign up and log in. The upper layers of the epidermis on average showed a 48-fold higher concentration following topical application of aciclovir ointment or cream 5% than after oral dosing, but the drug concentration in the basal epidermis -the site of herpes virus infection - was 2 to 3 times lower following topical application than after dosing.
Peak acyclovir concentrations in breast milk ranged from 0.5 to 2.3 times (median 1.4) the corresponding maternal acyclovir serum concentrations, and the acyclovir AUC in breast milk ranged from 1.4 to 2.6 times (median 2.2) maternal serum AUC. Do not refrigerate or freeze.The cream is filled into tubes.
The tubes are packed individually into cardboard boxes together with package leaflets.42-46 Booth Drive, Park Farm South, Wellingborough, Northamptonshire, NN8 6GTTo bookmark a medicine you must sign up and log in.To view the changes to a medicine you must sign up and log in. Continue for 5 or 10 days if healing does not occur.Zovirax cream is used for: Treating cold sores on the face or lips that are caused by the herpes virus. Other drugs affecting renal physiology could potentially influence the pharmacokinetics of aciclovir. However the accidental, repeated overdose of oral aciclovir, over several days has resulted in gastrointestinal effects (nausea and vomiting) and neurological effects (headache and confusion).Aciclovir is dialysable.Aciclovir is a pharmacologically inactive substance. Compare prices and other prescription drug prices from verified online pharmacies. For the Treatment of Herpes Simplex Virus Infections What Is Acyclovir Cream Used For? This site uses cookies. Our products can be classified into 10 main therapeutic categories, with particular emphasis on anti-infectives, central nervous system and cardiovascular medication. There was no difference in concentration between cream and ointment.The upper layers of the epidermis on average showed a 48-fold higher concentration following topical application of aciclovir ointment or cream 5% than after oral dosing, but the drug concentration in the basal epidermis -the site of herpes virus infection - was 2 to 3 times lower following topical application than after dosing.On the basis of continuous absorption the concentration increased as a function of time (higher drug concentrations being found 48 hours post topical dose than 24 hours post topical dose). The tubes consisting of aluminium are closed with a polyethylene cap. Cold sores (known medically as herpes labialis) are caused by a virus, usually herpes simplex virus type 1 (HSV-1). Such patients should be encouraged to consult a physician concerning the treatment of any infection,Cold Sore sufferers must avoid transmitting the virus particularly when active lesions are present.The cream must not be applied to the mucous membranes (e.g. Adult Dosing . acyclovir 5 % topical cream. Adults and children Apply a thin layer of cream to the affected area five times a day. imprint No data. It allows continued monitoring of the benefit/risk balance of the medicinal product. Suggested times are: 7am, 11am, 3pm, 7pm and 11pm. ‹ Back to Gallery. • You should space each application of Zovirax by four hours. Where sensitivity tests have been conducted, the reactive substances have most often been shown to be components of the cream rather than the active ingredient (aciclovir)Reporting suspected adverse reactions after authorization of the medicinal product is important. Aciclovir AL cream is effective in treatment of infections caused by the virus Herpes simplex.
Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. color white shape No data. However this is likely to be of little relevance to the cutaneous application of aciclovir.No interactions with other drugs have been described for topical aciclovir.A post-marketing aciclovir pregnancy registry has documented pregnancy outcomes in women exposed to any formulation of aciclovir. Vilerm Acyclovir Cream 5g.
Acyclovir cream is an antiviral medication that helps the body fight the infection by preventing the virus from multiplying. – It is particularly important to start treatment of recurrent episodes during the prodromal period or when the lesions first appear. Aciclovir is also incorporated into viral DNA by viral DNA polymerase, which results in chain termination, as aciclovir lacks a 3'-hydroxyl group, preventing addition of nucleotides by 3'-5'- linkage.In severely immunocompromised patients a longer or repeated treatment with aciclovir can lead to a selection of viral strains with reduced sensitivity.
Continue for 5 or 10 days if healing does not occur. Acyclovir cream is a prescription medication approved to treat cold sores.