Ampicillin for Injection, USP, the monosodium salt of [2S-[2 a, 5a, 6b(S*)]]- ... urine and its excretion can be delayed by concurrent administration of probene - cid. It can also be found in the Ampicillin has been used extensively to treat bacterial infections since 1961.In veterinary medicine, ampicillin is used in cats, dogs, and farm animals to treat:Horses are generally not treated with ampicillin, as they have low bioavailability of beta-lactams.The half-life in animals is around that same of that in humans (just over an hour). Requires JavaScript to be enabled. The concentrations should fall within the range specified. A change to oral ampicillin may be made when appropriate.Treatment of all infections should be continued for a minimum of 48 to 72 hours beyond the time that the patient becomes asymptomatic or evidence of bacterial eradication has been obtained. Although anaphylaxis is more frequent following parenteral therapy, it has occurred in patients on oral penicillins. It works by killing bacteria. Sometimes after starting treatment with antibiotics, patients can develop watery and bloody stools (with or without stomach cramps and fever) even as late as two or more months after having taken the last dose of the antibiotic. Cases of gonorrhea with a suspected primary lesion of syphilis should have darkfield examinations before receiving treatment. Ampicillin is the least serum-bound of all the penicillins, averaging about 20% compared to approximately 60 to 90% for other penicillins.

Therapy may be instituted prior to obtaining results of susceptibility testing.It is advisable to reserve the parenteral form of this drug for moderately severe and severe infections and for patients who are unable to take the oral forms. Before initiating therapy with a penicillin, careful inquiry should be made concerning previous hypersensitivity reactions to penicillins, cephalosporins, and other allergens. Intramuscular and intravenous injections should be administered within one hour after preparation, since the potency may decrease significantly after this period.While Ampicillin for Injection, USP 1 g and 2 g, are primarily for intravenous use, they may be administered intramuscularly when the 250 mg or 500 mg vials are unavailable. Oral absorption is less than 50% in cats and dogs, and less than 4% in horses.InChI=1S/C16H19N3O4S/c1-16(2)11(15(22)23)19-13(21)10(14(19)24-16)18-12(20)9(17)8-6-4-3-5-7-8/h3-7,9-11,14H,17H2,1-2H3,(H,18,20)(H,22,23)/t9-,10-,11+,14-/m1/s1Note: scroll down to "Search by name" and type "ampicillin" into the search bar. In such cases, discontinue the drug and substitute appropriate treatment.A high percentage (43 to 100 percent) of patients with infectious mononucleosis who receive ampicillin develop a skin rash. Skin Infections >1 year (40 kg): 200 mg/kg/day IV divided q6hr; not to exceed 14 days of therapy >1 year (>40 kg): 1.5 g (1 g ampicillin + 0.5 g sulbactam) to 3 g (2 g ampicillin … CLINITEST® is a registered trademark of Siemans Medical Solutions Diagnostics.H. It also serves as a convenient dosage form when small parenteral doses of the antibiotic are required.Only those solutions listed above should be used for the intravenous infusion of Ampicillin for Injection, USP. However, penetration into the cerebrospinal fluid and brain occurs only when the meninges are inflamed. Ampicillin injection is in a class of medications called penicillins.

In such instances, dissolve in 3.5 or 6.8 mL Sterile Water for Injection, USP or Bacteriostatic Water for Injection, USP, respectively.
For Administration by Intravenous Drip: Reconstitute as directed above (For Direct Intravenous Use) prior to diluting with Intravenous Solution. In patients with renal function impairment, ampicillin-class antibiotics can be removed by hemodialysis but not peritoneal dialysis.Patients weighing 40 kg (88 lbs) or more: 250 to 500 mg every 6 hours.Patients weighing less than 40 kg (88 lbs): 25 to 50 mg/kg/day in equally divided doses at 6- to 8-hour intervals.Patients weighing 40 kg (88 lbs) or more:500 mg every 6 hours.Patients weighing less than 40 kg (88 lbs): 50 mg/kg/day in equally divided doses at 6- to 8-hour intervals.In the treatment of chronic urinary tract and intestinal infections, frequent bacteriological and clinical appraisal is necessary. Therefore, the administration of ampicillin is not recommended in patients with mononucleosis.

The active form appears in the bile in higher concentrations than those found in serum. It is not known whether these patients are truly allergic to ampicillin.Diarrhea is a common problem caused by antibiotics which usually ends when the antibiotic is discontinued. influenzae, N. gonorrhoeae, N. meningitidis, Proteus mirabilisCarcinogenesis, Mutagenesis and Impairment of Fertility:To report SUSPECTED ADVERSE REACTIONS, contact FDA at 1-800-FDA-1088 or