However, the antiplatelet effect of berberine has never been investigated in patients receiving DAPT after PCI.The APLABE-PCI is a single-center, randomized, open-label, controlled, dose-escalating, parallel-group study, which is designed to assess the anti-platelet effect of berberine in approximately 64 patients receiving aspirin and clopidogrel who are at > 8 but ≤ 40 weeks after PCI.The total study duration is expected to be approximately 19 weeks per patient, including a screening period, a 12±1 week treatment period, and a 4±1 week follow-up period.The screening period will be up to 21 days. Berberine is thought to have a wide range of effects on the body, and therefore could theoretically interact with many different medications. Since the second day of the treatment period, the morning dose of berberine will be taken simultaneously with aspirin and clopidogrel in the morning.At the ends of Stage 1 (Visit 2), Stage 2 (Visit 3), and Stage 3 (Visit 4) (end of treatment, EOT), patients will return to the study center. Evidence suggests that berberine can lower blood pressure, increasing the risk of hypotension. Download Here Free HealthCareMagic App to Ask a DoctorAll the information, content and live chat provided on the site is intended to be for informational purposes only, and not a substitute for professional or medical advice. Dr. Brian Staiger is a licensed pharmacist in New York State and the founder of the Q+A website PharmacistAnswers.com.

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or just a possibility that the two won t mix for him Below, we discuss some of the potential drug interactions with berberine based on the information … Walking briskly daily helps increase the metabolism. Effect of a Combination of Berberine and Monacolin on CYP Enzymes: An Oral Cocktail Interaction Study in Healthy Volunteers 661 of red yeast rice and berberine, significantly improved the lipid profile in subjects with altered cholesterol and/or triglycerides or in subjects intolerant to statins [5]. It is true our metabolism slows down every decade.

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Clin Pharmacol Ther 1981 Mar;29(3):303-9. I didn t read the list of meds that you shouldn t take with Metoprolol until after he just now took the berberine... so I told him to tell me if he feels any increase in his heart beat and other things... is this a big thing? Detailed Answer: Use of this site is subject to our berberine is herbal product effective to treat type two diabetes.

Question: Good morning, I ... Metoprolol interaction with flexiril Taking metoprolol does smoking interact with this medication Does zinc interact with metoprolol Questions Answered By Kathy Shattler.

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On the first day of the treatment period (Visit 1), the morning dose (first dose) of berberine will be given 2-4 hour after aspirin and clopidogrel are taken together in the morning and immediately after the blood and urine samples for baseline platelet function tests are collected. COVID-19 is an emerging, rapidly evolving situation. All rights reserved. I would like to take Berberine HCI supplement for insulin resistance, but it can affect the same enzymes that metabolize my prescription medicines.