This is an online calculator to find the dosage of carboplatin AUC for a patient using the Calvert formula. In the text below the form there is more information on the formulas used and on target AUC.The Carboplatin calculator determines the therapy AUC dose based on the Cockcroft Gault equation and on target AUC.This method also provides useful information about the kidney function because it computes the creatinine clearance rate.■ CrCl for serum creatinine in mg/dL = [(140 - age) x Weight in kilograms (x 0.85 if female)] / (Serum Creatinine in mg/dL x 72)■ CrCl for serum creatinine in µmol/L = [(140 - age) x Weight in kilograms x (1.23 if male or 1.04 if female)] / (Serum Creatinine in µmol/L) The calculation of the ideal body weight by Devine’s formula:■ Male = (50 kg if male or 45.5 if female) + (2.3 x (Height in inches - 60))Creating an account is free and takes less than 1 minute.1. This Carboplatin AUC calculator determines the total dosage in mg based on the estimated creatinine clearance and target AUC plus the ideal body weight. This tool estimates the total Carboplatin dose (in mg) based on the Cockcroft Gault equation which provides the estimated creatinine clearance level which is then adjusted by the target AUC.The variables used are:■ Patient gender – to be used in the Cockcroft Gault equation and in Devine’s formula;■ Patient age – in years, to be used in the Cockcroft Gault equation;■ Patient weight – can be input in either lbs or kg;■ Patient height – can be specified in either ft and in or c… By using this form you agree with the storage and handling of your data by this website. Carboplatin dosage: prospective evaluation of a simple formula based on renal function. Gentamicin therapy. Usually, single intermittent courses should not be repeated until the neutrophil count is at least 2000 and the platelet count is at least 100,000. J Clin Oncol. Read our Get in touch with MDApp by using the following contact details:

Fill in the calculator/tool with your values and/or your answer choices and press Calculate.Please note that once you have closed the PDF you need to click on the Calculate button before you try opening it again, otherwise the input and/or results may not appear in the pdf.This tool estimates the total Carboplatin dose (in mg) based on the Cockcroft Gault equation which provides the estimated creatinine clearance level which is then adjusted by the target AUC.■ Patient gender – to be used in the Cockcroft Gault equation and in Devine’s formula;■ Patient age – in years, to be used in the Cockcroft Gault equation;■ Patient weight – can be input in either lbs or kg;■ Patient height – can be specified in either ft and in or cm;■ Target AUC – expected values range between 4 and 8 mg/mL/min;The Cockcroft and Gault equations when serum creatinine is in mg/dL:The Cockcroft and Gault formulas when serum creatinine is in µmol/L:The ideal weight result is converted in both kg and lbs for convenience, where (1 kg = 2.20462262 lbs).The carboplatin dosage value takes account of the target area concentration versus time curve and estimated GFR.

There is another dosing method, that involves body surface area, however, this is not as accurate.Target AUC values differ depending on the status of the patient:■ For patients already treated, target AUC should be around 4 – 7 mg/mL/min;■ For patients without previous treatment target AUC should be around 6 – 8 mg/mL/min.It is important to note that in some cases with fluctuant serum creatinine, the estimation may not be as exact, thus it won’t lead to an accurate Carboplatin dose either.3. (1989) Copyright 2014 - 2020 The Calculator .CO   |  All Rights Reserved  |  creatinine clearance level from the Cockcroft Gault equationCarboplatin dosage: prospective evaluation of a simple formula based on renal functionPrediction of creatinine clearance from serum creatinine The carboplatin dosage value is calculated by taking into account the target area concentration versus time curve and estimated GFR. Carboplatin dosage Calvert AH, Newell DR, Gumbrell LA, et al. Devine BJ. It uses creatinine clearance (GFR) and target area under curve for the dose estimation. 360 mg/m2 by IV on day 1 every 4 weeks (alternatively, the carboplatin dose may be calculated by the Calvert formula below). 1974; 8:650–5. A drug used to treat cancer is the carboplatin.

Carboplatin dose is calculated using the following formula: Carbo dose = target AUC(mg/ml/min) x (CrCl + 25)(ml/min) Please read the disclaimer before using this calculator. Estimated Clearance Equations Cockcroft and Gault equation: Male: CrCl (ml/min) = (140 - age) x wt (kg) / (serum creatinine x 72) Female: Multiply above result by 0.85

Read our CrCl for male = [(140 - age) x Weight in kilograms] / (Serum Creatinine in mg/dL x 72)CrCl for female = [(140 - age) x Weight in kilograms x 0.85] / (Serum Creatinine in mg/dL x 72)CrCl for male = [(140 - age) x Weight in kilograms x 1.23] / (Serum Creatinine in µmol/L)CrCl for female = [(140 - age) x Weight in kilograms x 1.04] / (Serum Creatinine in µmol/L)By using this form you agree with the storage and handling of your data by this website.