Akathisia is a movement disorder characterized by a subjective feeling of inner restlessness accompanied by mental distress and an inability to sit still. Although not all of these side effects may occur, if they do occur they may need medical attention.Check with your doctor immediately if any of the following side effects occur while taking prochlorperazine: Along with its needed effects, prochlorperazine (the active ingredient contained in Some side effects of prochlorperazine may occur that usually Check with your health care professional if any of the following side effects Blood dyscrasias included pancytopenia, thrombocytopenic purpura, leukopenia, agranulocytosis, eosinophilia, hemolytic anemia, and aplastic anemia.Mild leukopenia occurred in patients given high doses for prolonged durations.Acute dystonia was usually transitory, but was more commonly reported in young adults and children shortly after beginning treatment or increasing the dosage.Akathisia usually occurred in patients who were given large initial doses.Autonomic dysfunction included dry mouth, nasal congestion, headache, nausea, constipation, obstipation, adynamic Extrapyramidal reactions include acute dystonia, akathisia, parkinsonism, and tardive dyskinesia. This prospective, open-label, uncontrolled study evaluated a SmithKline Beecham, Philadelphia, PA. One study1looked at 229 adult patients receiving IM/IV prochlorperazine in the ED for nausea/vomiting for migraines.

Cerner Multum, Inc. "Australian Product Information." Akathisia is a movement disorder that makes it hard for you to stay still. The term was first used by Czech neuropsychiatrist Akathisia is usually grouped as a medication-induced Symptoms of akathisia are often described in vague terms such as feeling nervous, uneasy, tense, twitchy, restless, and an inability to relax.When misdiagnosis occurs in antipsychotic-induced akathisia, more antipsychotic may be prescribed, potentially worsening the symptoms.Visible signs of akathisia include repetitive movements such as crossing and uncrossing the legs, and constant shifting from one foot to the other.Akathisia involves increased levels of the neurotransmitter Akathisia can be miscoded in side effect reports from antidepressant clinical trials as "agitation, The presence and severity of akathisia can be measured using the The primary distinguishing features of akathisia in comparison with other syndromes are primarily subjective characteristics, such as the feeling of inner restlessness and tension.The controversial diagnosis of "pseudoakathisia" is sometimes given.As of 2007, published epidemiological data for akathisia was mostly limited to studies before the availability of Approximately one out of four individuals treated with first-generation antipsychotics have akathisia.The term was first used by Czech neuropsychiatrist Movement disorder involving a feeling of inner restlessness Please update this article to reflect recent events or newly available information. The natural course and duration of akathisia caused by a single dose of a parenteral drug is poorly described. Dystonia: 4 (1.7%) in the ED and 5 (2.6%) after discharge Overall, there was a 1 in 5 chance of an unpleasant reaction from prochlorperazine. Cerner Multum, Inc. "UK Summary of Product Characteristics." Those affected may fidget, rock back and forth, or pace, while some may just have an uneasy feeling in their body. In another study2, 44/100 ED patients developed ak… Compazine (prochlorperazine)." Study objective: Prochlorperazine (PCZ), a commonly used antiemetic and analgesic agent, is known to cause akathisia. We sought to evaluate the effectiveness of diphenhydramine in the treatment of akathisia induced by 10 mg intravenous prochlorperazine. You may report them to the The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records.