CRESTOR can be administered as a single dose at any time of day, with or without food. It is used to control levels of cholesterol and triglycerides in the blood.If it carries more cholesterol than the cells can use, too much cholesterol will accumulate, increasing the risk of arterial disease.

In this way, HDL protects the body from arterial disease.Like other statins, it prevents the production of LDL by suppressing HMG-CoA reductase. Use the pictures above to identify your dose. Myoglobin can damage the kidneys and cause kidney failure.

Crestor is indicated as adjunctive therapy to diet to reduce elevated Total-C, LDL-C, ApoB, nonHDL‑C, and triglycerides and to increase HDL‑C in adult patients with primary hyperlipidemia or mixed dyslipidemia.

Following dietary lead-in, patients were randomized to a sequence of treatments in conjunction with the TLC diet for 6 weeks each: rosuvastatin 10 mg followed by rosuvastatin 20 mg or rosuvastatin 20 mg followed by rosuvastatin 10 mg. Crestor reduced non HDL‑C (primary end point) and circulating remnant lipoprotein levels. The number of cases is adequate to exclude a ≥3 to 4-fold increase in congenital anomalies over the background incidence.

The most common adverse reactions that led to treatment discontinuation were: myalgia, hepatic enzyme increased, headache, and nausea Adverse reactions reported in ≥2% of patients and at a rate greater than placebo are shown in Table 2.In the JUPITER study, 17,802 participants were treated with rosuvastatin 20 mg (n=8901) or placebo (n=8901) for a mean duration of 2 years. It takes cholesterol away from cells and returns it to the liver.Cholesterol is either broken down in the liver or expelled from the body as waste. All rights reserved. Protect from moisture.Advise the patient to read the FDA-approved patient labeling (Patient Information).Patients should be instructed not to take 2 doses of Crestor within 12 hours of each other.Patients should be advised to report promptly unexplained muscle pain, tenderness, or weakness, particularly if accompanied by malaise or fever or if these muscle signs or symptoms persist after discontinuing Crestor.When taking Crestor with an aluminum and magnesium hydroxide combination antacid, the antacid should be taken at least 2 hours after Crestor administration.Advise females of reproductive potential of the risk to a fetus, to use effective contraception during treatment, and to inform their healthcare provider of a known or suspected pregnancy Advise women not to breastfeed during treatment with Crestor It is recommended that liver enzyme tests be performed before the initiation of Crestor and if signs or symptoms of liver injury occur.


The balance sheet for Crestor and other statins looks like this: These drugs cut the risk of heart attack, angina (chest pain), stroke, and death from cardiovascular disease by 30%. The starting rosuvastatin dosage for all children and adolescents was 5 mg once daily.
A proper diet and regular exercise should be maintained along with taking this medicine. However, medical professionals are concerned that by not using statins, patients could be putting themselves at risk of heart disease. Rosuvastatin may be used as monotherapy or an adjunct to other lipid-lowering therapy (e.g., …

In the U.S. general population, the estimated background risk of major birth defects and miscarriage in clinically recognized pregnancies is 2-4% and 15-20%, respectively.Limited published data on rosuvastatin have not shown an increased risk of major congenital malformations or miscarriage.

Rosuvastatin is used along with a proper diet to help lower "bad" cholesterol and fats (such as LDL, triglycerides) and raise "good" cholesterol (HDL) in the blood.