The main effects of tolterodine at 1 and 5 hours were an increase in The effect of 2 mg BID and 4 mg BID of DETROL immediate release (tolterodine IR) tablets on the QT and 5-HMT in extensive (EM) and poor (PM) metabolizers is provided in Table 3. The FDA is extending the warning to all atypical antipsychotics, not just those 4 that have been studied in patients with dementia and associated with increased risk, because the agency has concluded that the risk is related to common effects of this class of drugs. days and a single dose of warfarin 25 mg on day 4 had no effect on Tolterodine immediate release 4 mg (2 mg bid) had no effect on the hours, and the half-life of 5-HMT is 3.0 hours in females and 3.3 hours in males.Pharmacokinetic differences due to race have not been established.Overdosage with DETROL LA Capsules can potentially result in severe central anticholinergic effects
The impact of FDA alerts and label warnings was examined in 2 recently published studies of antipsychotic drug use. (moxifloxacin 400 mg QD) study in healthy male (N=25) and female (N=23) volunteers aged 18–55

the drug or its ingredients, or to fesoterodine fumarate extended-release tablets which, like DETROL Therefore, it should only be used by the patient concerned and no one else.This medication should be stored in a safe place beyond the reach of others.
metabolism leads to formation of the 5-carboxylic acid and N-dealkylated 5-carboxylic acid week 12 from baseline. affects you.Call your doctor for medical advice about side effects. People already suffering from a liver disease, or those whose alcohol consumption is very high, could be easily affected while taking acetaminophen.Some of the most common side effects of M367 are mentioned below:An overdose of M367 may cause other side effects such as:Some patients may even suffer some side effects due to sudden discontinuation of the medicine. If taking one of these drugs with acetaminophen-hydrocodone in unavoidable, then the dosage of either of the drugs needs to be lessened.Certain drugs multiply the amount of a chemical called serotonin in the body. You must, therefore, read the label carefully of any other medicine you intend to take to see if it contains M367.Remember to keep this and all other medicines for that matter, away from children and on no account should you ever share your medicines with others. Do not use a laxative (stool stimulant) without the permission of your doctor.It is advised not to use any other over-the-counter allergy, cold, painkiller or cough medication without consulting your doctor. Blood levels were not provided, making it not possible to determine whether the events resulted from antipsychotic drug toxicity or withdrawal. drug-metabolizing CYP enzymes. The effect of tolterodine 8 mg/day was not as large as that

DETROL stop taking DETROL LA and get emergency medical help right away.Medicines like DETROL LA can cause blurred vision, dizziness, and drowsiness.Do not drive, operate machinery, or do other dangerous activities until you know how DETROL LA As such it is very likely for them to suffer from many pain-related disorders and conditions. The FDA’s boxed warning decision was due to concerns over cerebrovascular events in elderly patients with dementia association with certain atypical antipsychotics. may include swelling of the face, lips, throat, or tongue. In case you are taking the medication properly at the prescribed timings you can take a missed dose immediately. The symptoms of EPS and withdrawal in newborns may include agitation, abnormally increased or decreased muscle tone, tremor, sleepiness, severe difficulty breathing, and difficulty in feeding. The structural formula appears below.Urispas® is supplied in tablets for oral administration.

The elimination half-life of tolterodine immediate release for both males and females is 2.4

Your doctor must immediately be informed if you observe the medicine not working as well as it used to in relieving your pain.In order to help prevent constipation while you are taking M367, consume 6 – 8 full glasses of water on a daily basis. Therefore, you need to be prepared for these consequences along with the projected benefits of the specific medicine. A black box warning is the most severe alert from the FDA. Your doctor may use a lower dose of DETROL LA if you are taking:Know the medicines you take.

Make sure to use M367 only for the prescribed period and not more. Benzodiazepines and drugs with strong anticholinergic effects have been linked to Alzheimer’s disease in people who take them. Arms and Interventions. It may harm them.This leaflet summarizes the most important information about DETROL LA. Please confirm that you would like to log out of Medscape.

suspension of DETROL LA is contraindicated in patients with urinary retention, gastric retention, or uncontrolled So you need to be extra cautious while driving or doing anything that requires you to be wide awake, aware and vigilant.