Time to Relief of Cluster Headache from Time of InjectionRisk of Myocardial Ischemia and/or Infarction, Prinzmetal’s Angina, Other Vasospasm-Related Events, Arrhythmias, and Cerebrovascular EventsConcomitant Use with Other Triptans or Ergot MedicationsWhat is the most important information I should know about IMITREX?Heart attack and other heart problems. The studies did not establish the efficacy of sumatriptan nasal spray compared to placebo in the treatment of migraine in adolescents.
Although the vast majority of those who have taken IMITREX have not experienced any significant side effects, some individuals have experienced serious heart problems and, rarely, considering the extensive use of IMITREX worldwide, deaths have been reported.
Imitrex (generic: sumatriptan) injection is a prescription medication used to treat migraine headaches once they have started. Each 0.5 mL of Imitrex Injection 8-mg/mL solution contains 4 mg of sumatriptan (base) as the succinate salt and 3.8 mg of sodium chloride, USP in Water for Injection, USP. In patients who experience symptoms or signs suggestive of non-coronary vasospasm reaction following the use of any 5-HTReports of transient and permanent blindness and significant partial vision loss have been reported with the use of 5-HTOveruse of acute migraine drugs (e.g., ergotamine, triptans, opioids, or combination of these drugs for 10 or more days per month) may lead to exacerbation of headache (medication overuse headache). With this device, the needle penetrates approximately 1/4 inch (5 to 6 mm). IMITREX Injection is a clear, colorless to pale yellow, sterile, nonpyrogenic solution for subcutaneous injection. The efficacy of IMITREX Injection is unaffected by whether or not migraine is associated with aura, duration of attack, gender or age of the patient, or concomitant use of common migraine prophylactic drugs (e.g., beta-blockers).
These trials did not establish the efficacy of oral IMITREX compared with placebo in the treatment of migraine in pediatric patients.
A fertility study (Segment I) by the subcutaneous route, during which male and female rats were dosed daily with sumatriptan prior to and throughout the mating period, has shown no evidence of impaired fertility at doses equivalent to approximately 100 times the maximum recommended single human dose of 6 mg on a mg/m
Demandez à votre pharmacien comment vous débarrasser des médicaments inutilisés ou périmés. Do not use if particulates and discolorations are noted.Imitrex Injection is contraindicated in patients with:The use of Imitrex Injection is contraindicated in patients with ischemic or vasospastic CAD.
It is taken by mouth, in the nose, or by injection under the skin.
Detoxification of patients, including withdrawal of the overused drugs, and treatment of withdrawal symptoms (which often includes a transient worsening of headache) may be necessary.Serotonin syndrome may occur with Imitrex Injection, particularly during coadministration with selective serotonin reuptake inhibitors (SSRIs), serotonin norepinephrine reuptake inhibitors (SNRIs), tricyclic antidepressants (TCAs), and MAO inhibitors Significant elevation in blood pressure, including hypertensive crisis with acute impairment of organ systems, has been reported on rare occasions in patients treated with 5-HTHypersensitivity reactions, including angioedema and anaphylaxis, have occurred in patients receiving IMITREX.
Injection. Do not use IMITREX for a condition for which it was not prescribed. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure.Ergot-containing drugs have been reported to cause prolonged vasospastic reactions. Le sumatriptan appartient à la classe des médicaments appelés agonistes sélectifs des récepteurs de la 5-hydroxytryptamine(également désignés « triptans »).
Common side effects include chest pressure, feeling tired, feeling of the world spinning, vomiting, tingling.
Effects generally occur within three hours. Two controlled clinical trials evaluating sumatriptan nasal spray (5 to 20 mg) in pediatric patients aged 12 to 17 years enrolled a total of 1,248 adolescent migraineurs who treated a single attack.
The other brands listed are trademarks owned by or licensed to their respective owners and are not owned by or licensed to the GSK group of companies. IMITREX Injection is a clear, colorless to pale yellow, sterile, nonpyrogenic solution for subcutaneous injection.
de l'agitation, des hallucinations, des battements de cœur rapides, une fièvre, des réflexes exagérés, de la nausée, des vomissements, de la diarrhée) après avoir employé le sumatriptan, demandez immédiatement des soins médicaux.Tous les contenus sont la propriété de MediResource Inc. 1996 – 2020.