≥1% incidence) adverse reactions in clinical trials with loperamide hydrochloride in acute diarrhoea were: constipation (2.7%), flatulence (1.7%), headache (1.2%) and nausea (1.1%). The studies produced no evidence of In a peri- and post-natal reproduction study in rats, oral administration of 40 mg/kg/day produced impairment of growth and survival of offspring.Small amounts of loperamide may appear in human breast milk. These symptoms are often difficult to distinguish from undesirable drug effects.Reporting suspected adverse reactions after authorisation of the medicinal product is important. Plasma levels are highest History of abnormal heart rhythm.
6.IMODIUM® (loperamide hydrochloride) is indicated for the control and symptomatic relief of acute nonspecific diarrhea and of chronic diarrhea associated with Patients should receive appropriate fluid and electrolyte replacement as needed.Following the first treatment day, it is recommended that subsequent IMODIUM® (loperamide hcl) doses (1 mg/10 kg body weight) be administered only after a loose stool. The concomitant administration of loperamide (4 mg single dose) and itraconazole, an inhibitor of CYP3A4 and P-glycoprotein, resulted in a 3 to 4-fold increase in loperamide plasma concentrations. Overdose can unmask existing Brugada syndrome. Hepatic dysfunction; monitor for CNS toxicity. However, at extremely high concentrations associated with overdoses (see section 4.4), loperamide has cardiac electrophysiological actions consisting of inhibition of potassium (hERG) and sodium currents, and arrhythmias.This medicinal product does not require any special storage conditions.Amber glass bottle with either a pilfer-proof aluminium screw cap coated on the inside with PVC or a child resistant polypropylene screw cap lined inside with an LDPE insert and a 5 ml or 10 ml polypropylene measuring cup.Imodium oral solution may be presented in bottle sizes of 30, 40, 50, 90 and 100 mls.50 - 100 Holmers Farm Way, High Wycombe, Bucks, HP12 4EGTo bookmark a medicine you must sign up and log in.To view the changes to a medicine you must sign up and log in. (21 times the human dose based on a body surface area comparison) produced marked impairment of fertility.

Specifically, experiments and medical studies show that the highest concentration of Imodium A-D in the blood is in the first 5 hours after the consumption of capsules. Drink lots of noncaffeine liquids unless told to drink less liquid by your doctor. The capsules have a light green body and a dark green cap with "JANSSEN" imprinted on one segment and "IMODIUM" on the other segment.

30 mL after the first loose stool; 15 mL after each subsequent loose stool; but no more than 60 mL in 24 hours. The starting dose should be between four and eight 5 ml doses per day in divided doses, depending on severity.

IMODIUM® (loperamide hcl) capsules contain FD&C Yellow No. If your child has diarrhea, take comfort knowing that IMODIUM A-D Oral Solution (liquid) for use with children is the only OTC brand anti-diarrheal that’s FDA-approved for children aged 6-11. Continue typing to refine. I wouldn't trade it for anything. A dosage of 16 mg (eight capsules) was rarely exceeded. Elimination of loperamide mainly occurs by oxidative N-demethylation. Of these, 26 trials were in acute diarrhoea (N=2755) and 5 trials were in chronic diarrhoea (N=321).The most commonly reported (i.e. Cardiac events including QT and QRS complex prolongation, torsade de pointes have been reported in association with overdose.
pass Capsules - each capsule contains 2 mg of loperamide hydrochloride. Other brands would leave me constipated for days after, but Imodium was easy on my stomach. Close more info about IMODIUM A-D LIQUID If possible, use weight to dose; otherwise use age.• use only enclosed dosing cup specifically designed for use with this product.

Call 1-877-895-3665 (toll-free) or 215-273-8755 (collect)Controls symptoms of diarrhea, including Travelers’ Diarrhea• you get abdominal swelling or bulging.

Oral administration of 20 mg/kg/day (approximately 11 times the human dose based on a body surface area comparison) and higher produced strong impairment of female fertility. All rights reserved. Dehydration, particularly in younger children, may further influence the variability of response to IMODIUM® (loperamide hcl) .In an 18-month rat study with oral doses up to 40 mg/kg/day (21 times the maximum human dose of 16 mg/day, based on a Fertility and reproductive performance was evaluated in rats using oral doses of 2.5, 10, and 40 mg/kg/day in one study, and 1, 5, 10, 20, and 40 mg/kg/day (females only) in a second study.

No dosage adjustment is required for the elderly.No pharmacokinetic data are available in patients with renal impairment.

FDA Rev date: 10/21/2005The adverse effects reported during clinical investigations of IMODIUM® (loperamide hydrochloride) are difficult to distinguish from symptoms associated with the diarrheal syndrome.

12 years and over.

Serious cardiac effects or death if taking more than directed. These may be signs of a serious condition.© Johnson & Johnson Consumer Inc. 2016.

Since persistent diarrhoea can be an indicator of potentially more serious conditions, Imodium should not be used for prolonged periods of time and the underlying cause of the diarrhoea should be investigated if clinical improvement is not observed within 48 hours of initiating treatment. Bowel regularity means a bowel movement every day. IMODIUM (loperamide hcl) should be used with caution in such patients because of reduced first