It may harm them.
Avoid sodium restriction or diuretic administration. endstream endobj 441 0 obj <> endobj 442 0 obj <> endobj 443 0 obj <>stream Taking lithium along with NSAIDs might increase the risk of lithium side effects. In addition, concomitant infection with elevated temperatures may also necessitate a temporary reduction or cessation of medication.The predominant form of chronic renal disease associated with long-term Lithium treatment is a chronic tubulointerstitial nephropathy (CTIN). All trademarks used are the properties of their respective owners.

Consider discontinuing Lithium if this syndrome occurs.The following adverse reactions are described in greater detail in other sections:Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in clinical practice.The following adverse reactions have been identified following use of Lithium. Taking lithium with these medications used for depression might cause there to be too much serotonin. Advise patients to discontinue Lithium treatment and contact their healthcare provider if clinical signs of Lithium toxicity such as diarrhea, vomiting, tremor, lack of muscle coordination, drowsiness, abnormal heart rhythm or muscular weakness occur Counsel patients on the adverse reactions of hyponatremia, when to seek medical attention, the importance of maintaining a normal diet including adequate salt intake and staying hydrated Caution patients about the risk of serotonin syndrome, particularly with the concomitant use of Lithium with otherserotonergic drugs including SSRIs, SNRIs, triptans, tricyclic antidepressants, fentanyl, tramadol, tryptophan, buspirone, St. John’s Wort, and with drugs that impair metabolism of serotonin (in particular, MAOIs, both those intended to treat psychiatric disorders and also others, such as linezolid) Advise patients that many drugs can interact with Lithium and to inform their doctor and pharmacist if they are taking any over the counter medication, including herbal medication, or are started on a new prescription Tell patients that Lithium may cause somnolence particularly when initiating treatment and to be cautious about operating vehicles or hazardous machinery, until they are reasonably certain that Lithium treatment does not affect them adversely Advise pregnant women of the potential risk to a fetus and/or neonate Advise women that breastfeeding is not recommended during treatment with Lithium Lithium carbonate tablets are a prescription medicine called mood-stabilizing agents used alone (monotherapy) for:It is not known if Lithium carbonate tablet is safe and effective in children under 7 years of age with bipolar I disorder.Before taking Lithium carbonate tablets, tell your healthcare provider if you:Using Lithium carbonate tablets with certain other medicines may affect each other causing possible side effects.
D�h������,��y>#��(���E�O��� =%77��K�q�x�8[����^JgkG#�� ���%1�W���ï�����-MY���n���j�������^��o�_�"��lg�}�E�f��]F���"֜X F1�0��E۝� �"r��qY�:M,-k�HQ�7�L�C ى��EV@��T5y��eg�8�3��\�y_�8�u�����f�t����T[e�p�\Y���r��rh���@�k���C�=zZY=AVE�L.7K.�d-ݍ�!�ph����A� ��.!�L. The risk is increased with concomitant use of other serotonergic drugs (including selective serotonin reuptake inhibitors, serotonin and norepinephrine reuptake inhibitors, triptans, tricyclic antidepressants, fentanyl, tramadol, tryptophan, buspirone, and St. John’s Wort) and with drugs that impair metabolism of serotonin, i.e., MAOIs Lithium is concentrated within the thyroid and can inhibit thyroid synthesis and release which can lead to hypothyroidism. After equilibrium, the apparent volume of distribution is 0.7 to 1 L/kg.Lithium is primarily excreted in urine, proportionally to its serum concentration. PROTECT FROM MOISTURE.Advise the patient to read FDA-approved patient labeling (Medication Guide).Advise patients that Lithium is a mood stabilizer, and should only be taken as directed. ​Treatment of acute manic and mixed episodes in patients 7 years and older [see Clinical Studies (14)] 2. Lithium-induced cases of hyperparathyroidism are more often multiglandular compared to standard cases.

Talk to your healthcare provider if you are taking lithium before taking "water pills. D����ą��������q�%�I In general, dose selection for an elderly patient should be cautious, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal, or cardiac function, and of concomitant disease or other treatment.As Lithium is eliminated primarily through the kidney, Lithium renal clearance is decreased in patients with abnormal renal function, and the risk of Lithium intoxication increases considerably in this setting. At delivery, vascular volume rapidly decreases and the renal clearance of Lithium may decrease to pre-pregnancy concentrations. It helps stabilize patients quickly. Nausea and general discomfort may also appear during the first few days of Lithium administration. Taking lithium along with these medications for depression might increase serotonin too much and cause serious side effects including heart problems, shivering, and anxiety. h�bbd```b``�"�A$3������� �KL�B`rXV����b��� �!D For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version.WebMD does not provide medical advice, diagnosis or treatment.This survey is being conducted by the WebMD marketing sciences department.All information will be used in a manner consistent with the WebMD

Paradoxically, some cases of hyperthyroidism have been reported including Grave’s disease, toxic multinodular goiter and silent thyroiditis.Long-term Lithium treatment is associated with persistent hyperparathyroidism and hypercalcemia. Patients weighing more than 30 kg started Lithium at 300 mg three times daily (900 mg/day) and could increase their dose by 300 mg every 3 days. CTIN patients might present with nephrotic proteinuria (>3.0g/dL), worsening renal insufficiency and/or nephrogenic diabetes insipidus.

The relationship between renal function and morphologic changes and their association with Lithium treatment has not been established. As an alternative option, urea, mannitol and aminophylline can induce a significant increase in Lithium excretion. Peak serum concentrations (TThe distribution space of Lithium approximates that of total body water, and the plasma protein binding is negligible. ?K.ee�kmMM��OM} ��Θ �"rf��e\=�l�?�5|{��� ��� rQ�|旟痵����� Pentazocine (Talwin) also increases serotonin. Restart treatment at the preconception dose when the patient is medically stable after delivery with careful monitoring of serum Lithium concentrations Start patients with mild to moderately impaired renal function (creatinine clearance 30 to 89 mL/min evaluated by Cockcroft-Gault) with dosages less than those for patients with normal renal function Each 300 mg tablet for oral administration contains: Lithium carbonate USP and is white to off-white, circular, biconvex, uncoated tablet debossed with “430” on one side and break line on other side.Lithium is contraindicated in patients with known hypersensitivity to any inactive ingredient in the Lithium carbonate tablet Chronic Lithium treatment may be associated with diminution of renal concentrating ability, occasionally presenting as nephrogenic diabetes insipidus, with polyuria and polydipsia.