The therapeutic regimen with methotrexate involves taking the drug taking one or two times per week.

A prospective studyLiver biopsies from psoriatics related to methotrexate therapy. So, now if your doctor asks you to get a treatment with methotrexate drug, you better inform him about your body conditions to avoid any further complications.

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In low doses, methotrexate is used in the treatment of rheumatologic conditions.

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School of Health Studies, University of Memphis, Memphis, Tennessee, USADepartment of Pharmaceutical Sciences, St. Jude Children's Research Hospital, New York, New York, USADepartment of Oncology, St. Jude Children's Research Hospital, New York, New York, USASchool of Health Studies, University of Memphis, Memphis, Tennessee, USADepartment of Hematology and Medical Oncology, Emory University School of Medicine, Atlanta, Georgia, USASchool of Health Studies, University of Memphis, Memphis, Tennessee, USADepartment of Pharmaceutical Sciences, St. Jude Children's Research Hospital, New York, New York, USADepartment of Oncology, St. Jude Children's Research Hospital, New York, New York, USASchool of Health Studies, University of Memphis, Memphis, Tennessee, USADepartment of Hematology and Medical Oncology, Emory University School of Medicine, Atlanta, Georgia, USADisclosures of potential conflicts of interest may be found at the end of this article.Use the link below to share a full-text version of this article with your friends and colleagues. Glucarpidase has recently been approved for the treatment of methotrexate toxicity; Supportive Care.

fluids with addition of acetazolamide when needed to keep urine pH > 7 maximizes methotrexate elimination and reduces further crystal formation in nephrons.

In color are the recommended doses of leucovorin based on the plasma MTX concentration at each time point after the start of the MTX infusion.