Studies have indicated that minocycline hydrochloride, the active ingredient of Minocycline 50 mg Tablets is a poison by the intravenous and intraperitoneal routes. Commonly reported side effects of minocycline include: headache. It is also excreted in bile.About a third of the drug may be excreted unchanged and although figures vary widely, about a third of this unchanged drug may appear in the urine and two thirds in the faeces.Studies have indicated that minocycline hydrochloride, the active ingredient of Minocycline 50 mg Tablets is a poison by the intravenous and intraperitoneal routes. You may also need to stop taking minocycline for a short time if you need surgery.This medicine can affect the results of certain medical tests.
An increase in the fibula growth rate has been observed in premature babies administered oral tetracyclines.Tetracyclines are known to cause a yellow to brown discoloration of the teeth and enamel hypoplasia in the developing child or foetus.Minocycline should be used with caution in patients with hepatic dysfunction or in conjunction with potentially hepatotoxic drugs, including alcohol.Rare cases of auto-immune hepatotoxicity and isolated cases of systemic lupus erythematosus (SLE) have been reported. Presenting features were headache and visual disturbances including blurring of vision, scotoma and diplopia. Ask your doctor about using a non hormonal method of birth control (such as a condom, diaphragm, spermicide) to prevent pregnancy while using this medicine.Minocycline can cause fetal harm and pass into breast milk. However, caution is advised in patients with severe renal impairment.Minocycline is not recommended in children under 12 years.To reduce the risk of ulceration and oesophageal irritation the tablets should be swallowed whole, with plenty of liquid, and whilst in an upright sitting or standing position.

Permanent tooth discolouration may occur in the developing infant and enamel hypoplasia has been reported.Dizziness, vertigo, headache, light-headedness, visual disturbances, tinnitus and impaired hearing (rarely) have occurred following administration of Minocycline. In common with other tetracyclines, Minocycline is thought to exert antibacterial activity by inhibition of protein synthesis. Minocycline is active against a wide range of gram negative and gram positive organisms, known to be sensitive to tetracyclines and against some tetracycline resistant strains of Organisms may be considered susceptible (infection likely to respond to minocycline therapy) if the Minimum Inhibitory Concentration is not more than 4 µg/ml. Minocycline is not removed in significant quantities by haemodialysis or peritoneal dialysis.Pharmacotherapeutic group: Antibacterials for systemic use, tetracyclines, ATC code: J01AA08.Minocycline is a tetracycline compound with bacteriostatic activity.

It crosses the placenta and diffuses into the milk of nursing mothers.About 75% of minocycline in the circulation is bound to plasma proteins. Dosages should be maximally separated. Administration of isotretinoin should be avoided shortly before, during and shortly after minocycline therapy. As with other serious adverse reactions, if any of these syndromes are recognised, the drug should be discontinued immediately: Acute toxicity studies indicate an LDTetracyclines can chelate metal cations to produce insoluble complexes. Eosinophilia may be present.Hyperpigmentation of various body sites including the skin, nails, teeth, oral mucosa, bones, thyroid, eyes (including sclera and conjunctiva), breast milk, lacrimal secretions and perspiration has been reported. In some cases involving these syndromes, death has been reported.

Wear protective clothing and use Get emergency medical help if you have signs of an allergic reaction to minocycline (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning in your eyes, skin pain, red or purple skin rash that spreads and causes blistering and peeling).Seek medical treatment if you have a serious drug reaction that can affect many parts of your body.

Take minocycline exactly as prescribed by your doctor. Such patients should be warned to avoid direct exposure to natural or artificial sunlight and to discontinue therapy at the first sign of skin discomfort.Patients with rare hereditary problems of galactose intolerance, the Lapp lactase deficiency or glucose-galactose malabsorption should not take this medicine.This medicinal product contains sunset yellow which may cause allergic reactions.Plasma prothrombin activity is depressed by tetracyclines. Using expired minocycline can cause damage to your kidneys.You should not take this medicine if you are allergic to minocycline or to similar If you are using minocycline to treat gonorrhea, your doctor may test you to make sure you do not also have To make sure this medicine is safe for you, tell your doctor if you have ever had:Tell your doctor right away if a pregnancy occurs while either the mother or the father is taking minocycline.


Unlike other tetracyclines, absorption of minocycline is not significantly impaired by food or moderate amounts of milk.Hypersensitivity to the active substance, tetracyclines or to any of the excipients listed in section 6.1.

• Serum sickness-like syndrome consisting of fever, urticaria or rash, and arthralgia, arthritis, joint stiffness or joint swelling. Absorption may be impaired by the concomitant administration of iron salts or antacids containing calcium, magnesium or aluminium salts. Rx only. Call your doctor for medical advice about side effects. Minocycline belongs to the class of medications called tetracycline antibiotics.

Minocycline is used to treat many different bacterial infections, such as urinary tract infections, respiratory infections, skin infections, severe acne, chlamydia, tick fever, and others. When suggestions are available use up and down arrows to review and ENTER to select. Normal doses of 200 mg followed by 100 mg every 12 hours produced plasma concentrations within the range of 1-4 μg/ml.