GSK assumes no responsibility for the content on the website. Available in orange and grape flavors, sold separately.10 mL every 12 hours, not to exceed 20 mL in 24 hours5 mL every 12 hours, not to exceed 10 mL in 24 hours2.5 mL every 12 hours, not to exceed 5 mL in 24 hours© 2020 GSK group of companies. Guaifenesin would be your go-to ingredient when battling a wet cough.© 2020 GSK group of companies. These could be signs of serious conditions.Cases of dextromethorphan abuse and dependence have been reported. Dry cough often occurs as a result of an upper respiratory tract infection in the nose and/or throat caused by a cold or flu. advice about side effects. It soothes your throat and delivers fast, powerful cough relief that lasts from morning until night. The activity of this enzyme is genetically determined. Available in great tasting orange and grape flavors, Robitussin 12 Hour Cough Medicine (OTC) soothes your throat and delivers fast, powerful relief. Caution is particularly recommended for adolescents and young adults as well as in patients with a history of drug abuse or psychoactive substances. Potent CYP2D6 enzyme inhibitors include fluoxetine, paroxetine, quinidine and terbinafine. Robitussin DM provides symptomatic relief for congested chests and dry irritating cough with occasional phlegm. Find a Robitussin retailer or e-commerce store today. Robitussin DM contains Dextromethorphan , a cough suppressant that reduces the amount of annoying coughs for up to 6 to 8 hours on a single dose.

Poor metabolisers and patients with concomitant use of CYP2D6 inhibitors may experience exaggerated and/or prolonged effects of dextromethorphan. Trade marks are owned by or licensed to the GSK group of companies. These are not all of the side effects that may occur. The content of this site is intended for US audiences only. 3. This class of medicine is in the list of drugs included in regulations under 5a of the Road Traffic Act 1988. This site uses cookies. Trade marks are owned by or licensed to the GSK group of companies. If you do not wish to leave this website, do not click on the links above.Take back your day with Robitussin 12 Hour. Genetically controlled O-demethylation (CYD2D6) is the main determinant of dextromethorphan pharmacokinetics in human volunteers.It appears that there are distinct phenotypes for this oxidation process resulting in highly variable pharmacokinetics between subjects. Measure liquid doses carefully. help if you have any side effects that bother you or do not go away. Dextromethorphan Hydrobromide Ph Eur 7.5mg per 5ml. Take with food if it causes an upset stomach. If you think there has been an overdose, call your poison control center or get medical care right away. It is not known whether dextromethorphan or its metabolites are excreted in human milk.This medicine can impair cognitive function and can affect a patient's ability to drive safely. Call your doctor for medical GSK assumes no responsibility for the content on the website. The two types of cough — wet cough and dry cough — are associated with different conditions. Robitussin Dry Cough Medicine. All drugs may cause side effects. Use Robitussin DM (guaifenesin and dextromethorphan liquid) as ordered by your doctor. Any accompanying symptoms should be actively sought and appropriately investigated/ treated. Take with or without food. taken, how much, and when it happened. Caution should therefore be exercised in patients who are slow metabolizers of CYP2D6 or use CYP2D6 inhibitors (see also section 4.5).- Patients with rare hereditary problems of fructose intolerance should not take this medicine because this product contains Sorbitol and Maltitol.- This product contains Amaranth (E123), which may cause allergic reactions.- This medicinal product contains 2.5% v/v ethanol (alcohol), up to 196 mg per dose, (equivalent to approx 1.6 ml wine per dose).

Clinical particulars. • Do not drive until you know how the medicine affects you If you have phenylketonuria (PKU), talk with your doctor. Follow all instructions closely. However, many people have no side effects or only have minor side effects. If concomitant use of CYP2D6 inhibitors and dextromethorphan is necessary, the patient should be monitored and the dextromethorphan dose may need to be reduced.Although dextromethorphan has been in widespread use for many years without apparent ill-consequence, there are no specific data on its use during pregnancy. *Compared to Robitussin Cough + Chest Congestion DM 10mL. Dextromethorphan, or DXM for short, is an ingredient that works in the brain and central nervous system to target signals that trigger the cough reflex and ultimately help reduce the urge to cough. Pharmaceutical form.

In the event of massive overdose the following symptoms may be observed: coma, respiratory depression, convulsions. By clicking the link(s) above, you will be taken to an external website that is independently operated and not managed by GSK. All rights reserved. Call your doctor or get medical

Cough relief products that contain dextromethorphan (cough suppressant) and guaifenesin (cough expectorant) can provide relief for your dry cough and wet cough. 4.1 Therapeutic indications . Bright pink clear liquid for oral administration. Continue typing to refine. In concomitant use with quinidine, plasma concentrations of dextromethorphan have increased up to 20-fold, which has increased the CNS adverse effects of the agent. Wet Cough.