I consider myself 75-90% in remission of the severe, daily pain of the arthritis. With brand names Azulfidine and Sulfazine, Sulfasalazine is a disease-modifying anti-rheumatic drug . It was a difficult time as I went from being very social/active to a lot of pain, swelling and 'dis'ability in a mattter of months (a very sudden and severe onset). Methotrexate is basically a mild chemotherapy drug...before you start on that or anything stronger, understand what it is and the possible side effects. I am currently off any meds except enstilar for my skin and other than some manageble pain, I am back to (almost) where I was prior to diagnosis. Sulfasalazine seems like the least aggressive treatment, so I'm inclined to choose that one, but I do not have any experience or know anyone that has been on it. More research is needed to uncover the full potential of sulfasalazine in dermatology. Its immunomodulatory, anti-inflammatory, and antiproliferative properties make it a potential therapeutic option for various dermatological disorders. I'm 29 and have recently been diagnosed with PA. My Rheumatologist has offered me my own choice of trying either Sulfasalazine or Methotrexate, and I'm not sure which route to go! Sulfasalazine … My name is Carol. Charitable Incorporated Organisation Number: 1180666 ScienceDirect ® is a registered trademark of Elsevier B.V.Sulfasalazine in dermatology: A lesser explored drug with broad therapeutic potential© 2020 Published by Elsevier Inc. on behalf of Women's Dermatologic Society.ScienceDirect ® is a registered trademark of Elsevier B.V. And P. I'm hoping to find friends on this site who also have the same. I weened myself off of meds with naproxen as needed. By continuing you agree to the Copyright © 2020 Elsevier B.V. or its licensors or contributors. After one appt that I left crying (after he told me I would end up crippled), I went to another rheumatologist who advised that if i thought I might want to conceive within the next few years, I should come off everything! As I understand it, there is more or less a kind of ladder of meds, Sulfa being on the lowest rung. Methotrexate was the best for me. First discovered and used in RA treatment nearly 70 years ago, Sulfasalazine is normally prescribed for arthritis … Introduction. Any feedback would be greatly appreciated.There is a more modern alternative to metho and that is Otezla.Speaking from experience, I think it is the best treatment to hit the meds market so far and I am glad my NHS specialist suggested giving it a try :thumbup:Thanks for the recommendation. I was 29 when I was diagnosed and told that to go on methotrexate that I would have to go on birth control (which I was not on) and would have to be off of the methotrexate for a min of 6 mnths before trying to conceive. What is Sulfasalazine. Sulfasalazine is an aminosalicylate primarily used in the treatment of rheumatoid arthritis and ulcerative colitis. You will be told (and perhaps it's true) that eventually certain meds will become ineffective and you will need something stronger. In this review, we compare PsA treatment recommendations or guidelines developed by one national organization [ACR and National Psoriasis Foundation (NPF) in 2018], one regional organization (EULAR in 2015), and one international organization (the Group for Research and Assessment of Psoriasis and Psoriatic Arthritis … Sulfasalazine (Azulfidine ®, Azulfidine EN-tabs ®) is a medication sometimes used to treat psoriatic arthritis, although it is not approved for this use.Azulfidine and Azulfidine EN-tabs are similar … Sulfasalazine (SSZ; salazopyrin, sulfasalazopyridine, salicylazosulfapyridine) is a U.S. Food and Drug Administration–approved disease-modifying antirheumatic drug (DMARD) commonly used in the treatment of rheumatoid arthritis … I didn't like the sound of any of it and I'm so glad I didn't just listen to the advice (pressure) of the doctor. The present article is a detailed review of the pharmacology, modes of action, side effects, and contraindications of sulfasalazine, along with an up-to-date review of the evidence underlying its use in various dermatological conditions.We use cookies to help provide and enhance our service and tailor content and ads. However, the level of evidence supporting its efficacy and safety in dermatology is limited.