Do not chew or crush it. These reactions have been chosen for inclusion due to either their seriousness, frequency of reporting, or causal connection to sumatriptan or a combination of these factors.Ergot-containing drugs have been reported to cause prolonged vasospastic reactions. There are also reports in patients where no such predisposing factors are apparent. You may report side effects to Health Canada at 1-866-234-2345.This drug may make you dizzy or drowsy. However if the first dose of sumatriptan does not help, do not take another dose for the same attack.Do not have more than 2 injections, or 2 doses of nasal spray, or more than 300mg of tablets in 24 hours.Do not take more than the prescribed amount in any 24-hour period. Initially 6 mg for 1 dose, followed by 6 mg after at least 1 hour if required, to be taken only if migraine recurs (patient not responding to initial dose should not take second dose for same attack), dose to be administered using … In 4 of the 5 trials, there was a statistically significant greater percentage of patients with headache response at 2 hours in the 20-mg group when compared with the lower dose groups (5 and 10 mg). Take the sumatriptan packet or leaflet inside it plus any remaining medicine with you.Like all medicines, sumatriptan can cause side effects. Read the instructions that come with your medicine to find out how to use the pre-filled syringe (auto-injector) and how to get rid of it safely afterwards.Use the pre-filled syringe to inject 1 dose.
If you find tablets difficult to swallow, some come with a line in the middle to help you break them in half. If your symptoms are only partly relieved, or if your Unusual taste or irritation/numbness/tingling of the nose or throat may occur after using the spray. Detoxification of patients, including withdrawal of the overused drugs, and treatment of withdrawal symptoms (which often includes a transient worsening of headache) may be necessary.Serotonin syndrome may occur with Sumatriptan Nasal Spray, particularly during coadministration with selective serotonin reuptake inhibitors (SSRIs), serotonin norepinephrine reuptake inhibitors (SNRIs), tricyclic antidepressants (TCAs), and MAO inhibitors Significant elevation in blood pressure, including hypertensive crisis with acute impairment of organ systems, has been reported on rare occasions in patients treated with 5-HTLocal irritative symptoms such as burning, numbness, paresthesia, discharge, and pain or soreness were reported in approximately 5% of patients in controlled clinical trials and were noted to be severe in about 1%. It is available as a nasal spray, and this route of administration may be preferable for individuals experiencing nausea and/or vomiting, although absorption of the drug occurs primarily in the gut rather than the nasal Intranasal sumatriptan is effective as an abortive treatment for Migraine is a highly disabling condition for the individual and also has wide-reaching implications for society, healthcare services, and the economy. Other reported clinical experience has not identified differences in responses between the elderly and younger patients. Taking too many migraine medicines or taking them too often is linked to something called "medication overuse headaches". Sumatriptan Nasal Spray is indicated for the acute treatment of migraine with or without aura in adults.The recommended adult dose of Sumatriptan Nasal Spray for the acute treatment of migraine is 5 mg, 10 mg, or 20 mg. Recor when and where each migraine attack started, what you were doing at the time, and what you ate that day.Sumatriptan will not stop your contraception working. For patients with multiple cardiovascular risk factors who have a negative cardiovascular evaluation, consider administering the first dose of Sumatriptan Nasal Spray in a medically supervised setting and performing an electrocardiogram (ECG) immediately following administration of Sumatriptan Nasal Spray. Remove the sumatriptan spray from the package only when you are ready to use it. They're usually mild and short lived. For such patients, consider periodic cardiovascular evaluation in intermittent long-term users of Sumatriptan Nasal Spray.Life-threatening disturbances of cardiac rhythm, including ventricular tachycardia and ventricular fibrillation leading to death, have been reported within a few hours following the administration of 5-HTSensations of tightness, pain, pressure, and heaviness in the precordium, throat, neck, and jaw may occur after treatment with Sumatriptan Nasal Spray and are usually non-cardiac in origin. This medicine is most commonly given as a spray into the nose but it can also be given as a tablet. Do not give Sumatriptan Nasal Spray to other people, even if they have the same symptoms you have. Sumatriptan Nasal Spray is not used to treat other types of headaches such as hemiplegic (that make you unable to move on one side of your body) or basilar (rare form of migraine with aura) migraines. Therefore, the use of Sumatriptan Nasal Spray in patients receiving MAO-A inhibitors is contraindicated Because their vasospastic effects may be additive, coadministration of Sumatriptan Nasal Spray and other 5-HTCases of serotonin syndrome have been reported during coadministration of triptans and SSRIs, SNRIs, TCAs, and MAO inhibitors Data from a prospective pregnancy exposure registry and epidemiological studies of pregnant women have not detected an increased frequency of birth defects or a consistent pattern of birth defects among women exposed to sumatriptan compared with the general population In the U.S. general population, the estimated background risk of major birth defects and of miscarriage in clinically recognized pregnancies is 2% to 4% and 15% to 20%, respectively.
In 2 trials, a 5-mg dose was also evaluated.In all 5 trials utilizing the market formulation and recommended dosage regimen, the percentage of patients achieving headache response 2 hours after treatment was significantly greater among patients receiving Sumatriptan Nasal Spray at all doses (with one exception) compared with those who received placebo. Sumatriptan tablets, nasal spray and injections are available on prescription.
If you find tablets difficult to swallow, some come with a line in the middle to help you break them in half. If your symptoms are only partly relieved, or if your Unusual taste or irritation/numbness/tingling of the nose or throat may occur after using the spray. Detoxification of patients, including withdrawal of the overused drugs, and treatment of withdrawal symptoms (which often includes a transient worsening of headache) may be necessary.Serotonin syndrome may occur with Sumatriptan Nasal Spray, particularly during coadministration with selective serotonin reuptake inhibitors (SSRIs), serotonin norepinephrine reuptake inhibitors (SNRIs), tricyclic antidepressants (TCAs), and MAO inhibitors Significant elevation in blood pressure, including hypertensive crisis with acute impairment of organ systems, has been reported on rare occasions in patients treated with 5-HTLocal irritative symptoms such as burning, numbness, paresthesia, discharge, and pain or soreness were reported in approximately 5% of patients in controlled clinical trials and were noted to be severe in about 1%. It is available as a nasal spray, and this route of administration may be preferable for individuals experiencing nausea and/or vomiting, although absorption of the drug occurs primarily in the gut rather than the nasal Intranasal sumatriptan is effective as an abortive treatment for Migraine is a highly disabling condition for the individual and also has wide-reaching implications for society, healthcare services, and the economy. Other reported clinical experience has not identified differences in responses between the elderly and younger patients. Taking too many migraine medicines or taking them too often is linked to something called "medication overuse headaches". Sumatriptan Nasal Spray is indicated for the acute treatment of migraine with or without aura in adults.The recommended adult dose of Sumatriptan Nasal Spray for the acute treatment of migraine is 5 mg, 10 mg, or 20 mg. Recor when and where each migraine attack started, what you were doing at the time, and what you ate that day.Sumatriptan will not stop your contraception working. For patients with multiple cardiovascular risk factors who have a negative cardiovascular evaluation, consider administering the first dose of Sumatriptan Nasal Spray in a medically supervised setting and performing an electrocardiogram (ECG) immediately following administration of Sumatriptan Nasal Spray. Remove the sumatriptan spray from the package only when you are ready to use it. They're usually mild and short lived. For such patients, consider periodic cardiovascular evaluation in intermittent long-term users of Sumatriptan Nasal Spray.Life-threatening disturbances of cardiac rhythm, including ventricular tachycardia and ventricular fibrillation leading to death, have been reported within a few hours following the administration of 5-HTSensations of tightness, pain, pressure, and heaviness in the precordium, throat, neck, and jaw may occur after treatment with Sumatriptan Nasal Spray and are usually non-cardiac in origin. This medicine is most commonly given as a spray into the nose but it can also be given as a tablet. Do not give Sumatriptan Nasal Spray to other people, even if they have the same symptoms you have. Sumatriptan Nasal Spray is not used to treat other types of headaches such as hemiplegic (that make you unable to move on one side of your body) or basilar (rare form of migraine with aura) migraines. Therefore, the use of Sumatriptan Nasal Spray in patients receiving MAO-A inhibitors is contraindicated Because their vasospastic effects may be additive, coadministration of Sumatriptan Nasal Spray and other 5-HTCases of serotonin syndrome have been reported during coadministration of triptans and SSRIs, SNRIs, TCAs, and MAO inhibitors Data from a prospective pregnancy exposure registry and epidemiological studies of pregnant women have not detected an increased frequency of birth defects or a consistent pattern of birth defects among women exposed to sumatriptan compared with the general population In the U.S. general population, the estimated background risk of major birth defects and of miscarriage in clinically recognized pregnancies is 2% to 4% and 15% to 20%, respectively.
In 2 trials, a 5-mg dose was also evaluated.In all 5 trials utilizing the market formulation and recommended dosage regimen, the percentage of patients achieving headache response 2 hours after treatment was significantly greater among patients receiving Sumatriptan Nasal Spray at all doses (with one exception) compared with those who received placebo. Sumatriptan tablets, nasal spray and injections are available on prescription.