The developmental and health benefits of breast-feeding should be considered along with the mother’s clinical need for CATAFLAM and any potential adverse effects on the breastfed infant from the CATAFLAM or from the underlying maternal condition.One woman treated orally with a diclofenac salt, 150 mg/day, had a milk diclofenac level of 100 µg/L, equivalent to an infant dose of about 0.03 mg/kg/day. “Currently, the most effective medications for the many types of arthritis require monitoring by healthcare providers, so as not to be improperly used by the public,” Torum told Healthline. If clinical signs and symptoms consistent with liver disease develop, or if systemic manifestations occur (e.g., eosinophilia, rash, etc. Voltaren Rapid 12.5 Liquid Capsules. Voltaren Gel may be used to treat arthritis pain in the arms (hands, wrists, and elbows) and in the legs (feet, ankles, and knees). Patients taking angiotensin converting enzyme (ACE) inhibitors, thiazide diuretics, or loop diuretics may have impaired response to these therapies when taking NSAIDs Monitor blood pressure (BP) during the initiation of NSAID treatment and throughout the course of therapy.The Coxib and traditional NSAID Trialists’ Collaboration meta-analysis of randomized controlled trials demonstrated an approximately two-fold increase in hospitalizations for heart failure in COX-2 selective-treated patients and nonselective NSAID-treated patients compared to placebo-treated patients. Our website services, content, and products are for informational purposes only.
The concomitant use of diclofenac and anticoagulants have an increased risk of serious bleeding compared to the use of either drug alone.Serotonin release by platelets plays an important role in hemostasis. Healthline Media does not provide medical advice, diagnosis, or treatment. Do not use combination therapy with Voltaren Gel and an oral NSAID unless the benefit outweighs the risk.The following adverse reactions are discussed in greater detail in other sections of the labeling:Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared with rates in the clinical trials of another drug and may not reflect the rates observed in practice.During clinical development, 913 patients were exposed to Voltaren Gel in randomized, double-blind, multicenter, vehicle-controlled, parallel-group studies in osteoarthritis of the superficial joints of the extremities. Data from observational studies regarding potential embryofetal risks of NSAID use in women in the first or second trimesters of pregnancy are inconclusive. Additionally, 583 patients were exposed to Voltaren Gel in an uncontrolled, open-label, long-term safety trial in osteoarthritis of the knee.

In these patients, administration of an NSAID may cause a dose-dependent reduction in prostaglandin formation and, secondarily, in renal blood flow, which may precipitate overt renal decompensation. You can ask your pharmacist or healthcare provider for information about NSAIDs that is written for health professionals.This Medication Guide has been approved by the U.S. Food and Drug Administration. The dosing card is re-usable. But like other over-the-counter medications, medical professionals warn that consumers shouldn’t be lulled into thinking it’s safe for everyone to use for an endless amount of time.It’s a topical nonsteroidal anti-inflammatory drug (NSAID), one of the most common drugs to treat various forms of arthritis. No overall differences in effectiveness or safety were observed between these subjects and younger subjects, but greater sensitivity to the effect of NSAIDs in some older individuals cannot be ruled out.Diclofenac, as with any NSAID, is known to be substantially excreted by the kidney, and the risk of toxic reactions to Voltaren Gel may be greater in patients with impaired renal function.
Voltaren Rapid 12.5 tablets are available in packs of 10 or 20.