Epub 2006 Oct 17.Curr Obes Rep. 2015 Dec;4(4):451-9. doi: 10.1007/s13679-015-0177-4.Ther Clin Risk Manag. Box 670559, 231 Albert Sabin Way, Cincinnati, OH 45267-0559; A binge was defined according to DSM-IV-TR criteria. For permissions, please e-mail journals.permissions@oup.com.This article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model ( 5Human Psychopharmacology: Clinical and Experimental, Vol. Response to treatment was also analyzed categorically, with response categories defined by the percentage reduction in binge frequency from baseline: remission=cessation of binges; marked=a 75%–99% reduction; moderate=a 50%–74% reduction; and none=less than a 50% reduction For laboratory measures, including weight and body fat, we computed the mean difference between endpoint and baseline measures and then compared the treatment groups by using the t test.
2Expert Opinion on Investigational Drugs, Vol. 50, No. Doses ranging from 50 to 1400 mg/day were stated to be effective in these reports. 31 March 2007 | American Journal of Psychiatry, Vol. 1, No. 15, No. 18, No. Let them know what other treatments you have tried as well as what has and has not worked for you in the past. 61, No. 12International Journal of Eating Disorders, Vol. 2Child and Adolescent Psychiatric Clinics of North America, Vol.

8, No. 49 October 2014 | Current Treatment Options in Psychiatry, Vol. At baseline, there were no significant differences between the treatment groups in demographic or clinical features (Fifty-eight patients (28 receiving topiramate, 30 given placebo) had at least one postrandomization efficacy measure.

2003 Nov;64(11):1335-41. doi: 10.4088/jcp.v64n1109.McElroy SL, Kotwal R, Guerdjikova AI, Welge JA, Nelson EB, Lake KA, D'Alessio DA, Keck PE, Hudson JI.J Clin Psychiatry. Limitations include a small sample size and a high drop-out rate in both study groups.Most users should sign in with their email address.

Also, there were no cases of nephrolithiasis or acute angle glaucoma, rare but serious side effects associated with topiramate The reduction in binge frequency and the overall improvement observed with topiramate in this study are at least comparable to the results reported in studies of SSRIs The mechanism of action of topiramate in binge eating disorder is unknown. 40, No. 39, No. 12, No. Of the remaining 61 patients, 30 were randomly assigned to topiramate, and 31 were assigned to placebo. Please enable it to take advantage of the complete set of features! Unable to load your delegates due to an error 6International Journal of Eating Disorders, Vol. Please enable it to take advantage of the complete set of features! 51 April 2011 | Journal of Health Psychology, Vol. New 2013 incidence peak in childhood narcolepsy: more than vaccination?

Titration to the minimum maintenance dose should be attempted over 5–7 weeks of … We conducted a placebo-controlled randomized clinical trial of topiramate to assess efficacy in SRED.Thirty-four participants with an ICSD-2/ICSD-3 diagnosis of SRED with >6 months of symptoms and ≥3 sleep-related eating episodes per week were randomized to placebo or topiramate with flexible dosing to a maximum dosage of 300 mg for 13 weeks. 12, No. 29, No. 25, No. The trial consisted of a 2- to 5-week screening period, a 14-week treatment period, and a 2-week treatment taper and discontinuation period. Thank you for submitting a comment on this article.
It furthers the University's objective of excellence in research, scholarship, and education by publishing worldwideFor full access to this pdf, sign in to an existing account, or purchase an annual subscription.Departments of Psychiatry and Neurology, Massachusetts General Hospital 42, No. 71 March 2007 | American Journal of Psychiatry, Vol. 12, No. Side effects were prominent for topiramate. COVID-19 is an emerging, rapidly evolving situation. 1Journal of Diabetes and its Complications, Vol. The … 5Best Practice & Research Clinical Gastroenterology, Vol. Small case series’ have demonstrated efficacy of topiramate in SRED. Unable to load your collection due to an error Binge-Eating Disorder (BED) is characterized by recurrent binge eating without extreme behaviors to lose weight (e.g., self-induced vomiting, misuse of laxatives) resulting in marked distress, feelings of loss of control, and association with overweight or obesity. 6International Journal of Eating Disorders, Vol.