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We comply with the HONcode standard for trustworthy health information - In vitro studies using human liver microsomes indicate that fenofibrate and fenofibric acid are not inhibitors of cytochrome (CYP) P450 isoforms CYP3A4, Cyp2D6, CYP2E1, or CYP1A2. Fenofibrate is a fibric acid derivative whose lipid modifying effects reported in humans are mediated via activation of Peroxisome Proliferator Activated Receptor type alpha (PPARα). A risk to the suckling child cannot be excluded. This occurrence may represent a failure of efficacy in patients with severe hypertriglyceridemia, a direct drug effect, or a secondary phenomenon mediated through biliary tract stone or sludge formation Muscle toxicity, including rare cases of rhabdomyolysis, with or without renal failure, has been reported with administration of fibrates and other lipid-lowering agents. As this medicinal product contains lactose patients with rare hereditary problems of galactose intolerance, Lapp lactase deficiency or glucose-galactose malabsorption should not take this medicine. Tricor 145 mg se koristi zajedno s dijetom siromašnom masnoćama i drugim nemedicinskim liječenjem kao što su tjelovježba i smanjenje tjelesne težine, kako bi se snizila razina masnoća u krvi. Tricor 145 mg. oblong, white, imprinted with LOGO, FO. If an overdose is suspected, treat symptomatically and institute appropriate supportive measures as required. TRICOR® 48 mg and 145 mg (fenofibrate tablets) DESCRIPTION . In rats and mice, liver tumours have been found at high dosages, which are attributable to peroxisome proliferation. Pagine riservate agli utenti soci aderenti PLEFAS Pagine riservate agli utenti soci Pagine riservate agli utenti registrati ... Tricor 54 mg. oblong, yellow, imprinted with a, TA. Therefore, Tricor® may be taken without A food-effect study involving administration of the new 145 mg tablet formulation of fenofibrate to healthy male and female subjects under fasting conditions and with a high fat meal indicated that exposure (AUC Metabolism and excretion: After oral administration, fenofibrate is rapidly hydrolysed by esterases to the active metabolite fenofibric acid. Even if you have no symptoms, tests can help your doctor determine if TriCor is effective.TriCor is only part of a complete program of treatment that may also include diet, exercise, weight control, and other medications. Tricor® 145 mg, film-coated tablets contains 145 mg of fenofibrate nanoparticles. ) . Fertility: Reversible effects on fertility have been observed in animals (see section 5.3). Call your doctor for medical advice about side effects. For hyperlipidaemic patients taking oestrogens or contraceptives containing oestrogen it should be ascertained whether the hyperlipidaemia is of primary or secondary nature (possible elevation of lipid values caused by oral oestrogen).

TRICOR (fenofibrate tablets), is a lipid regulating agent available as tablets for oral administration. Fenofibrate is not a substrate for CYP 3A4. The above stated effects of fenofibrate on lipoproteins lead to a reduction in very low- and low density fractions (VLDL and LDL) containing apoprotein B and an increase in the high density lipoprotein fraction In addition, through modulation of the synthesis and the catabolism of VLDL fractions fenofibrate increases the LDL clearance and reduces small dense LDL, the levels of which are elevated in the atherogenic lipoprotein phenotype, a common disorder in patients at risk for coronary heart disease. In such cases The risk of muscle toxicity may be increased if the drug is administered with another fibrate or an HMG-prescription of fenofibrate with HMG-CoA reductase inhibitor or another fibrate should be reserved to patients with severe combined dyslipidaemia and high cardiovascular risk without any history of muscular disease and with a close monitoring of potential muscle toxicity. This Information is Confidential

Tricor is indicated as adjunctive therapy to diet to reduce elevated low-density lipoprotein cholesterol (LDL-C), total cholesterol (Total-C), Triglycerides and apolipoprotein B (Apo B), and to increase high-density lipoprotein cholesterol (HDL-C) in adult patients with primary hypercholesterolemia or mixed dyslipidemia. TriCor dosing information.

The maximum dose is 145 mg …

Your doctor may occasionally change your dose.TriCor may be taken with or without food. Known photoallergy or phototoxic reaction during treatment with fibrates or ketoprofen, Hypersensitivity to the active substance(s) or to any of the excipients listed in section 6.1. Click Studies on mutagenicity of fenofibrate have been negative. Tricor usual adult dose is 48-154 mg… TRICOR (fenofibrate tablets), is a lipid regulating agent available as tablets for oral administration. For adult patients with hypertriglyceridemia, the initial dose is 48 to 145 mg per day. Follow your diet, medication, and exercise routines very closely.Store at room temperature away from moisture, heat, and light.Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. In order for us to create your customized HealthSavvy programs, we need a little more information about the health topic(s) that you are interested in. No unchanged fenofibrate can be detected in the plasma. Usual Adult Dose of TriCor for Hyperlipoproteinemia Type IIa (Elevated LDL): 145 mg orally once a day. Site users seeking medical advice about their specific situation should consult with their own physician.