A low dose dihydrotestosterone, DHT gel, labeled Andactrim™, also from Solvay, has been available in Europe for almost a decade.
i was just perscribed it and I'm a little weary ! Although each type of delivery system has a different appearance and texture, all of them are designed to deliver the highest concentration of active ingredient deep into the dermis. Topical testosterone can cause side effects in women and children who come in contact with it on your skin or clothing. There are transdermal creams and gels that are also designed to deliver multiple active ingredients at one time. A compounded hormone combination cream is an example of a multi-drug transdermal delivery system (ie. VersaBase Cream is an elegant, yet durable, topical cream and an ideal compounding base for topical and vaginal hormone replacement therapy (HRT). When applied on a daily basis, topical testosterone provides 24-hour duration of action, which naturally mimics the rise and fall of testosterone throughout the day.Transdermal delivery systems are self-contained dosage forms that, when applied to unbroken skin, are designed to deliver the drug(s) through the skin to systemic circulation. It is not intended to diagnose, treat, cure, or prevent any health problem. Always consult a physician or qualified health professional on any matters regarding your health or on any opinions expressed within this website. Common strengths found in compounded topical testosterone products range between 5%-20% testosterone. Depending on the individual sometimes less is absorbed, therefore it is important to follow up with laboratory testing so that the testosterone dose might be titrated to maximize transdermal absorption.Men require a daily supply of 7mg-10mg of testosterone to achieve a physiological level in the upper-quartile and to reverse the symptoms of hypogonadism. The highest concentration available for most transdermal hormone creams and gels is 20%, or 200mg/ml. The cost for compounded testosterone creams are far less expensive than 1% AndroGel® Likewise, cheaper generic alternatives to can be compounded by many pharmacists. Testosterone is purchased in raw form (testosterone base) by compounding pharmacies and drug manufactures to be used to create various testosterone products. If the areas where you are applying the cream are covered in hair, you may want to consider shaving those areas. Apply the cream one hour prior to physical activity or sexual activity. Androderm® is available in two strengths, as either a 2mg or 4mg transdermal patch. AndroGel® is a very expensive, low dose 1% (10mg/ml), testosterone product on the market since July 2000, which provides a safe, alcohol based gel containing testosterone in low physiologic doses. Do not use more than once a day. Medquest Pharmacy 200mg/ml versabase cream How To Properly Use Trans-Scrotal Testosterone Cream. A specific concentration of testosterone base is then added to a transdermal delivery system either in the form of an alcohol-based gel or transdermal cream. Important Information for Current and Future Patients (COVID-19). 5% equals a 50mg/ml concentration of testosterone; 7% equals 70mg/ml; 10% equals 100mg/ml; etc. For example, cream based delivery systems apply better to skin in sensitive areas, such as the scrotum or inner thighs. Testim®, released in 2004, seems to have slightly better absorption rate than AndroGel, making it more efficient, but it also has a low concentration of testosterone (1%) therefore the increased absorption rate may not provide significant elevation of total testosterone. It is extremely important to avoid using an alcohol-free cream as alcohol is harmful for scrotal skin health. Testosterone Versabase cream for toughening thining of external female gentials. Another common dispensing container is called “Topi-Click”, which looks like a deodorant container. It simulates the natural moisturizing barrier of the skin through its emulsion system and rubs in quickly, leaving a soft and silky feel. Manufactured brand-name transdermal testosterone products are available only as either a gel or transdermal patch.Compounding pharmacies usually carry a variety of TDS bases that can be used to make a transdermal hormone.
Attempting testosterone cream for at least 2-3 months and checking blood tests at the 6-8 week mark will allow for adequate time to determine if it is working for you. Due to the low concentration, larger amounts are required for adequate testosterone replacement in men. Another reason compounded transdermal testosterone might more effective is due to the ability to provide patients a transdermal delivery system that works best for them.