Zofran (ondansetron) is used to prevent nausea and vomiting caused by surgery or cancer medicines. The orally disintegrating tablet may work faster and is administered by allowing the … Drugs provider for the most current information.The recipient will receive more details and instructions to access this offer.By clicking send, you acknowledge that you have permission to email the recipient with this information.The recipient will receive more details and instructions to access this offer.By clicking send, you acknowledge that you have permission to email the recipient with this information.
This was followed by the oral administration of ondansetron ranging from 4 to 24 mg daily for 3 days.
Commonly used antacids include:Additionally, avoiding foods that may cause heartburn may be

In the US trial, ZOFRAN was administered intravenously (only) in three doses of 0.15 mg/kg each for a total daily dose of 7.2 to 39 mg. be used for prevention or treatment of nausea and vomiting.

Zofran is often These may include:Dr. Kevin Davis is a licensed pharmacist with experience in retail and hospital pharmacy. How do you space omeprazole and sucralfate properly? How long does the effect of Tums last? Good luck. In our latest question and answer, the pharmacist discusses how often you can safely take Zofran (ondansetron).If I took Zofran 8mg this morning at 8 am can I take another now?Ondansetron (Zofran) is a prescription medication that can I work with prescribe for our patients? Anyone taking zofran?

Do not take more often than told by the doctor.

Diseases & Conditions Dosage in Hepatic Impairment In patients with severe hepatic impairment (Child-Pugh score of 10 or greater), do not exceed a total daily dose of 8 mg [see Use in Specific Populations (8.6), Clinical Pharmacology (12.3)]. Since I missed my Prilosec this morning, is it okay to take it now? Dose: 0.15 mg/kg/dose IV q4h x3 doses; Start: 30min before chemo; Max: 16 mg/dose [PO route, moderately-emetogenic chemo, 4-11 yo] Dose: 4 mg PO q4h x3 doses, then 4 mg PO q8h until 1-2 days after chemo complete; Start: 30min before chemo [PO route, moderately-emetogenic chemo, 12-17 yo] vomiting including:Zofran may cause headache, drowsiness, diarrhea, and constipation. It is not meant to be chewed or swallowed like other tablet forms. Controlled studies in pregnant women show no evidence of fetal risk.Mechanism not fully characterized; selective 5-HT3 receptor antagonist; binds to 5-HT3 receptors both in periphery and in CNS, with primary effects in GI tractHas no effect on dopamine receptors and therefore does not cause extrapyramidal symptomsBioavailability: 56-71% (PO); food increases extent of absorption (17%)Peak plasma time: IV, end of infusion; IM, 30 min; PO, 2 hr (tablet) or 1 hr (soluble film)Extensive hepatic metabolism, with hydroxylation followed by glucuronide (indole ring) or sulfate conjugation; metabolized by CYP2D6 and partly by CYP1A2 and CYP3A4Metabolites: Glucuronide conjugate, sulfate conjugate (inactive)Half-life: 2-7 hr (children <15 years); 3-7 hr (adults); patients with mild to moderate hepatic impairment, 12 hr; patients with severe hepatic impairment (Child-Pugh class C), 20 hrY-site: Acyclovir, allopurinol, aminophylline, amphotericin B, amphotericin B cholesteryl sulfate, ampicillin, ampicillin/sulbactam, amsacrine, cefepime, cefoperazone, 5-fluorouracil (5-FU; at 1 mg/mL ondansetron and 16 mg/mL 5-FU; may be compatible at 0.8 mg/mL 5-FU and up to 160 mcg/mL ondansetron), furosemide, ganciclovir, lorazepam, meropenem (at 50 mg/mL meropenem and 1 mg/mL ondansetron; may be compatible at 1 mg/mL each), methylprednisolone, piperacillin, sargramostim, sodium bicarbonateAdditive (partial list): Cisplatin, cyclophosphamide, cytarabine, decarbazine, dacarbazine with doxorubicin(? ), doxorubicin, etoposide, hydromorphone, meropenem (incompatible at 20 g/L meropenem), methotrexate, morphine sulfateSyringe: Alfentanil, atropine, dexamethasone (incompatible at 0.67 mg/mL dexamethasone and 1.07 mg/mL ondansetron), fentanyl, glycopyrrolate, meperidine, metoclopramide, midazolam, morphine sulfate, naloxone, neostigmine, propofolY-site (partial list): Alatrofloxacin, aldesleukin, azithromycin, bleomycin, carboplatin, cisplatin, cladribine, clindamycin, cyclophosphamide, cytarabine, dactinomycin, dopamine, heparin, hydromorphone, magnesium sulfate, meperidine, morphine sulfate, paclitaxel, potassium chloride, topotecan, vancomycin, vinblastine, vincristine, zidovudinePostoperative nausea and vomiting: No dilution necessary for 2 mg/mL vialsChemotherapy-induced nausea and vomiting: Dilute IV injection (2 mg/mL vials, not premixed injection) in 50 mL D5W or NSInfuse over 15 minutes after further dilution with 50 mL NS/D5WInject undiluted over at least 30 seconds, preferably over 2-5 minutesAdding plans allows you to compare formulary status to other drugs in the same class.To view formulary information first create a list of plans.