Accessed January 2011. Available online at http://kidshealth.org/parent/system/medical/test_valproic.html. Available online at http://www.medscape.com/viewarticle/551786. Accessed January 2011.Kidshealth. Wagner ML, Graves NM, Leppik IE, et al: The effect of felbamate on valproic acid disposition. Therefore, a patient with a condition resulting in lower-than-normal amounts of protein in their blood may be at increased risk of having a supratherapeutic or excess amount of circulating valproic acid and therefore require monitoring of both total and free valproic acid levels.Brunton LL, Chabner BA, Knollmann BC, Goodman & Gilman's the Pharmacological Basis of Therapeutics. A valproic acid test measures the amount of valproic acid, which is an anticonvulsant medicine, in a blood sample. Diseases & Conditions They are sometimes called "normal" values.
(March 1, 2017) MayoClinic.com. 1186482-overview © 2001-2020 by American Association for Clinical Chemistry Accessed on 3/25/07. Last reviewed July 16, 2013. Available online at http://www.aruplab.com/guides/ug/tests/0099310.jsp. Accessed on 9/24/18. It may also be ordered when someone experiences a troublesome level of side effects and/or develops complications. Valproic Acid. Epub 2009 Nov 4.Ann Pharmacother.
They are typically found to the right of your results.If you do not have your lab report, consult your healthcare provider or the laboratory that performed the test(s) to obtain the reference range.Laboratory test results are not meaningful by themselves. Available online through http://www.nami.org. To determine the concentration of valproic acid in your blood; the purpose is to maintain a therapeutic level and monitor toxicity.At regular intervals to monitor the drug's level or when a person shows signs of toxicityNo special test preparation is needed, but talk to your healthcare practitioner about the timing of sample collection. "Valproic acid is a drug that is used primarily to control certain seizures by lessening their severity and frequency. (October 10, 2009) American Cancer Society. It is important that you communicate with your physician so that together you can integrate the pertinent information, such as age, ethnicity, health history, signs and symptoms, laboratory and other procedures (radiology, endoscopy, etc. Medication Lists: Valproic Acid. Seizures and Epilepsy: Hope Through Research. Clipboard, Search History, and several other advanced features are temporarily unavailable. Once a stable blood concentration in the therapeutic range has been achieved, the valproic acid level may then be monitored at regular intervals to ensure that it remains within the therapeutic range.The test may be ordered when a person's condition does not appear to be responding to valproic acid to determine whether the concentration is too low, the medication is ineffective, and/or to determine if someone is complying with therapy (taking the valproic acid regularly). The toxic level is >100 mcg/mL.Valproic acid is a broad-spectrum antiseizure drug with a narrow therapeutic window. If you log out, you will be required to enter your username and password the next time you visit. eMedicineHealth [On-line information]. Muscle contractions during a seizure can lead to an injury and, in some cases, recurrent seizures can eventually lead to progressive brain damage but, for most people, there will be little or no residual damage.Sometimes valproic acid is prescribed for bipolar disorder, a psychiatric condition characterized by cycles of depression and mania that may last for days, weeks, months, or years.
COVID-19 is an emerging, rapidly evolving situation. After serial levels reveal values consistently in the therapeutic range, the valproic acid level may then be monitored at less frequent but regular intervals to ensure that it remains within this range.Additional testing of levels may be required if a patient’s condition is not responding to the medication to determine whether the concentration is too low, to determine if the medication is ineffective, or to confirm the patient's compliance with the medication. Logistics
Concentrations drawn after a dose typically represent a peak level Trough concentrations are usually drawn within 30 minutes prior to a dose If a level was not … Available online at https://medlineplus.gov/druginfo/meds/a682412.html.