conducted a study to elucidate the effect of buspirone in two groups of Flinders Sensitive Line (FSL) rats: “depressed” (experimental group) and “non-depressed” (control group). You’ll need to work with your doctor to find an antidepressant that helps with your depression symptoms and doesn’t result in unwanted side effects. If experienced, these tend to have a Less Severe expression 1. If you’re experiencing weight change on Buspar, its effect on the endocrine system could be a contributing factor.In the event that Buspar proves effective in treating depressive symptoms, this might lead to normalization of your appetite, eating habits, and/or activity level. Common medications that may interact with buspirone include: Alcohol may worsen the side effects of buspirone such as drowsiness and dizziness.Note that this list is not all-inclusive and includes only common medications that may interact with buspirone. Buspar (buspirone) is a medication [of the azapirone classification] that’s most commonly administered for the treatment of generalized anxiety disorder (GAD). J trauma, . – data from all available trials are currently unanimous in suggesting that Buspar is a “weight neutral” medication. For example, if Buspar is causing somnolence that leads to weight gain, then the concurrent use of a stimulatory agent like caffeine may prevent weight gain by offsetting the somnolence.If you have a history of using substances (e.g. Some variables that likely influence Buspar-mediated weight change include: Buspar dosage; length of Buspar treatment; concurrent substance use; prior substance use; baseline body weight; lifestyle; and genetics.The exact dose of Buspar that you administer on a daily basis could influence whether you experience weight change throughout treatment. It is often used in erection problems. To be clear, clinically relevant weight change is defined as an increase or decrease in body weight of at least 7% from baseline (pre-Buspar use).Buspar packaging data lists “weight gain” and “weight loss” as infrequent side effects – or reactions that occur in less than 1% of all users. If you notice any other effects, check with your healthcare professional.Call your doctor for medical advice about side effects. All rights reserved. Included below are some hypothetical ways in which Buspar might cause someone to gain or lose weight while under its influence. More specifically, Buspar acts as a full agonist at presynaptic 5-HT1A receptors and a partial agonist of postsynaptic 5-HT1A receptors. Although this was an animal study that cannot be generalized to humans, it supports the concept that buspirone treatment might counteract or Nishi, Kanemaru, Hasegawa, et al. Before testing any of the weight management strategies below, contact a medical doctor to verify that they’re safe in accordance with your present medical status.If you’ve used Buspar for a moderate duration, leave a comment noting whether you’ve experienced weight change that you believe is attributable to the medication. healthy) or unfavorable (i.e. It was noted that buspirone was well-tolerated and maintained its therapeutic efficacy for over a year.In this case, it is apparent that buspirone was able to decrease anxiety associated with eating. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. Nervous It is known that untreated anxiety (and chronic stress) can detrimentally affect gut health, so perhaps treating the anxiety with Buspar could yield favorable changes in gut bacteria composition – possibly leading to normalization of appetite and healthy weight change (among overweight persons).It is known that increases in plasma prolactin concentrations can cause weight gain, whereas increases in plasma growth hormone levels may modestly reduce body fat (in certain regions like the stomach).