Such evaluations are increasingly relevant to third-party payers, health maintenance organizations, and other parties involved in managed care.  KS

Specifically, we compared Procardia XL with Adalat CC.  LBreuer  ME The costs and effects of switching calcium channel blockers: evidence from Medicaid claims data From the Departments of Medicine, Emory University School of Medicine (Dr Hall) and Morehouse School of Medicine (Dr Reed), Atlanta, Ga, and Wayne State University School of Medicine, Detroit, Mich (Dr Flack); and the Departments of Medicine (Dr Flack) and Public Health Sciences (Drs Yunis and Preisser), Bowman Gray School of Medicine, Winston-Salem, NC. In the nifedipine GITS group, 3 adverse events (2 probably drug-related; 1 serious) were reported by 2 of 59 patients.

 WC Prevalence of hypertension in the US adult population: results from the Third National Health and Nutrition Examination Survey, 1988-1991.  RLShannon 0000000016 00000 n  CJungerwirth  et al. Human blood pressure determination by sphygmomanometry.  MRKong Burt sign up for alerts, and moreto access your subscriptions, sign up for alerts, and moreto access your subscriptions, sign up for alerts, and moreto download free article PDFs, sign up for alerts, customize your interests, and moreto make a comment, download free article PDFs, sign up for alerts and more Short-acting medications work quickly, but their effects last only a few hours.

Pharmacist's Letter includes: 12 issues every year, with brief articles about new meds and hot topics; 300+ CE courses, including the popular CE-in-the-Letter; Quick reference drug comparison charts; The effects observed in mechanistic experiments in vitro and studied in intact animals and man are compatible with this mechanism of action and are typical of the class. Moreover, potential study participants were excluded if they had 1+ or more edema at baseline.The results support the hypothesis that these 3 dihydropyridine CCBs can be used interchangeably without regard for potential differences in efficacy or safety in African American patients. 0000003624 00000 n  MCGardner However, patients were seen on morning visits. 0000044604 00000 n  JAStoddard Clipboard, Search History, and several other advanced features are temporarily unavailable.  LBreuer  EWeir

Long-acting medications are slowly released to provide a longer lasting effect. Eligibility was determined after receiving no antihypertensives for at least 3 weeks, during which time compliance to placebo was at least 80% by pill counts.Major study exclusion criteria included a serum creatinine level above 212 µmol/L (2.4 mg/dL), 4+ proteinuria on routine urinalysis, uncontrolled diabetes mellitus (fasting glucose level, >11 mmol/L [198 mg/dL]), aspartate aminotransferase levels of greater than 1.5 times upper normal limit, 1+ or more pretibial edema on results of clinical examination, known secondary causes of hypertension, comorbid cardiovascular conditions (previous stroke, coronary artery disease, arrhythmias, or heart failure), pregnancy or planned pregnancy during the study, average alcohol intake of 3 or more drinks per day, and (because of the ambulatory BP monitoring) working the night shift or having a mid–upper arm circumference of greater than 37.5 cm such that technically valid computerized BP recordings were less likely.All centers had to receive institutional review board approval before receipt of antihypertensives, and all patients gave written informed consent before enrollment.All protocol visits occurred in the mornings, 22 to 26 hours after the last dose of blinded medication. Joint National Committee on Prevention, Detection, Evaluation and Treatment of High Blood Pressure (JNC VI), The Sixth Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure.  EFCarter

Background Hypertension is a prevalent disease among African Americans, and successful treatment rates are low. 0000006781 00000 n  SPRipa 0000004346 00000 n

Select one or more newsletters to continue. All rights reserved. Results They are the only once-daily-dosed, extended-release forms of nifedipine available. Elsevier Science  AAllenby It binds to calcium channels with high affinity and specificity and inhibits calcium flux into cardiac and smooth muscle. Granberry  WK Please enable it to take advantage of the complete set of features!  H-WM Comparison of the efficacy and safety of nifedipine coat-core versus amlodipine in the treatment of patients with mild-to-moderate essential hypertension.