following stability data when maintained at room temperature up to 86ºF (30ºC): Single-dose vial – 14 days. 0000008485 00000 n Desmopressin Acetate Injection 4 mcg/mL dosage must be determined for each patient and adjusted according to the pattern of response. 0000005303 00000 n 0000006369 00000 n Add 1.2 mL of Sterile Water for Injection to the vial and shake vigorously until all the drug is dissolved. Each monograph contains stability data, administration guidelines, and methods of preparation.

0000008660 00000 n 0000007003 00000 n trailer << /Size 80 /Info 39 0 R /Encrypt 43 0 R /Root 42 0 R /Prev 50602 /ID[ Decrease bleeding following cardiac bypass: 0.3 mcg/kg ivpb. 0000011597 00000 n

The tendency toward tachyphylaxis (lessening of response) with repeated administration given more frequently than every 48 hours should be considered in treating each patient. 15 Ortho Biotech 888-227-5624 Estradiol/norethindrone acetate transdermal system (CombiPatch) Prior to dispensing, refrigerate at 36º to 46ºF (2º to 8ºC). 15 Unopened multi-dose vial – seven days.

Supplied: 4 mcg/ml-1 ml vial.. The usual dosage range in adults is 0.5 mL (2 mcg) to 1 mL (4 mcg) daily, administered intravenously or subcutaneously, usually in two divided doses. DDAVP P ® Injection (desmopressin acetate) 4 mcg/mL Rx only DESCRIPTION DDAVP® Injection (desmopressin acetate) 4 mcg/mL is a synthetic analogue of the natural pituitary hormone 8-arginine vasopressin (ADH), an antidiuretic hormone affecting renal water conservation. Neither GlobalRPh Inc. nor any other party involved in the preparation of this document shall be liable for any special, consequential, or exemplary damages resulting in whole or part from any user's use of or reliance upon this material.

Intermittent intravenous infusion For adults and children weighing greater than 10 kg, dilute dose in 50 mL of 0.9% Sodium Chloride for injection. Intravenous admixtures – preparation and infusion guidelines. BY ACCESSING OR USING THIS SITE, YOU AGREE TO BE BOUND BY THE TERMS AND CONDITIONS SET FORTH IN THE DISCLAIMER. 0000009315 00000 n 0000002662 00000 n Desmopressin Acetate Pharmacokinetics Absorption Bioavailability.

%PDF-1.4 %���� Longer DOA. 0000001491 00000 n This reference contains standard dilutions including IV admixture drug concentration, infusion volumes, and infusion rates.

41 0 obj << /Linearized 1 /O 44 /H [ 1646 395 ] /L 51550 /E 17575 /N 9 /T 50612 >> endobj xref 41 39 0000000016 00000 n GEODON for Injection (ziprasidone mesylate) should only be administered by intramuscular injection and should not be administered intravenously. 0000008228 00000 n 0000010018 00000 n Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration whenever solution and container permit.The authors make no claims of the accuracy of the information contained herein; and these suggested doses and/or guidelines are not a substitute for clinical judgment. Patients receiving intravenous fluids must be …

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Provide short term protection for uremic hemorrhagic tendency: 0.3 mcg/kg ivpb q8h x 2 doses (diminishing response). 0000002483 00000 n 0000004795 00000 n

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Direct intravenous injection No dilution necessary. 0000014463 00000 n Diabetes Insipidus: This formulation is administered subcutaneously or by direct intravenous injection. Single-dose vials require reconstitution prior to administration. 0000001144 00000 n The morning and evening doses should be separately adjusted for an adequate diurnal rhythm of water turnover. 0000001646 00000 n 0000004774 00000 n 0000006021 00000 n 0000011319 00000 n Renal concentration capacity testing in children below the age of 1 year should only be performed under carefully supervised conditions in hospital. 0000005324 00000 n 0000014275 00000 n OCTOSTIM® has an antidiuretic effect. a Minimally absorbed from GI tract following oral administration; bioavailability is about 5% compared with intranasal administration and about 0.16% compared with IV administration of the drug.

For patients who have been controlled on intranasal desmopressin acetate and who must be switched to the injection form, either because of poor intranasal absorption or because of the need for surgery, the comparable antidiuretic dose of the injection is about one-tenth the intranasal dose. After dispensing, store at room Less vasopressor activity. 0000003562 00000 n desmopressin acetate are produced after repeated administration. 0000014314 00000 n About 10–20% of a dose is absorbed through nasal mucosa following intranasal administration. 0000007563 00000 n


0000006000 00000 n 0000002020 00000 n Diabetes insipidus: 2-4 mcg/day IV push or SC. (Synthetic analog of vasopressin-posterior pituitary hormone). Particular attention should be paid to the possibility of the rare occurrence of an extreme decrease in plasma osmolality that may result in seizures which could lead to coma. 0000006982 00000 n Patients receiving this drug should be cautioned to reduce their ingestion of fluids for at least 6 hours after receiving the drug. 0000003895 00000 n Response should be estimated by two parameters: adequate duration of sleep and adequate, not excessive, water turnover. For children weighing less than 10 kg, …