Atomoxetine, sold under the brand name Strattera, among others, is a medication used to treat attention deficit hyperactivity disorder (ADHD). dosage depends on indication: 200 to 800 mg, 24 hourly, IM; 200 to 400 mg, 12 hourly, PO; 25 mg, 8 hourly, PO It is taken by mouth. The levo enantiomer shows better/similar pharmacological actions and lower incidence of toxic effects than both dextro as well as the … In Iran, atomoxetine is sold under brand names including Stramox. Chemical Formula. CAS registry number (Chemical Abstracts Service) 0023672-07-3.

National Center for Advancing Translational Sciences (NCATS), Levosulpiride is also claimed to have mood elevating properties. It has a role as a dopaminergic antagonist, an antidepressant, an antiemetic and an antipsychotic agent.

Antiemetic agent. Levosulpiride is prescribed to the patients having bowel disorders. Unknown by Ravizza Farmaceutici JTG7R315LK In Australia, Portugal and Romania, atomoxetine is sold under the brand name Strattera. Schizophrenia 7. Possibly Marketed Outside US CCN1CCC[C@H]1CNC(=O)C2=C(OC)C=CC(=C2)S(N)(=O)=O Levosulpiride is classified as an antipsychotic medicine, also known as tranquilizer or neuroleptic.The drug has a number of properties that include antiemetic as it prevents vomiting, antidepressant, antipsychotic and anti-dyspeptic as in anti-indigestion. Premature ejaculation 8. 341. Levosulpiride [RV 12309, L-sulpiride, levosulpride, Dislep® 25, Levopride®, Levopraid®] is a potent dopamine D2 receptor blocker that was originated by Ravizza Farmaceutici (now AbbVie). Rec.INN. It may be used alone or along with stimulants. Dyspepsia 10. Levosulpiride, sold under the brand name Neoprad is a substituted benzamide antipsychotic, reported to be a selective antagonist of dopamine D2 receptor activity on both central and peripheral levels. Possibly Marketed Outside US Levosulpiride is the levo enantiomer of sulpiride. Hallucinations 5. InChIKey=BGRJTUBHPOOWDU-NSHDSACASA-N

~ 0.013, 1, ~ 45 and ~ 77 muM at D2, D3, D4, D1 and D5 receptors respectively). Emes… The generic Levosulpiride is manufactured by one company. (S)-(-)-sulpiride is an optically active form of sulpiride having (S)-configuration. Single-drug overdoses involving over 1500 mg of atomoxetine have not resulted in death.The recommended treatment for atomoxetine overdose includes use of 4-Hydroxyatomoxetine, the major active metabolite of atomoxetine in CYP2D6 extensive metabolizers, has been found to have sub-micromolar affinity for Orally administered atomoxetine is rapidly and completely absorbed.The half-life of atomoxetine varies widely between individuals, with an average range of 4.5 to 19 hours.Atomoxetine is excreted unchanged in urine at <3% in both extensive and poor CYP2D6 metabolizers, with >96% and 80% of a total dose being excreted in urine, respectively.Chinese adults homozygous for the hypoactive CYP2D6*10 allele have been found to exhibit two-fold higher AUCs and 1.5-fold higher maximum plasma concentrations compared to extensive metabolizers.Japanese men homozygous for CYP2D6*10 have similarly been found to experience two-fold higher AUCs compared to extensive metabolizers.Atomoxetine may be quantitated in plasma, serum or whole blood in order to distinguish extensive versus poor metabolizers in those receiving the drug therapeutically, to confirm the diagnosis in potential poisoning victims or to assist in the forensic investigation in a case of fatal overdosage.Atomoxetine is manufactured, marketed, and sold in the United States as the In 2017 the FDA approved the generic production of atomoxetine by four pharmaceutical companies.In India, atomoxetine is sold under brand names including Axetra, Axepta, Attera, Tomoxetin, and Attentin.

ATC (Anatomical Therapeutic Chemical Classification) N05AL07. Irritable bowel syndrome 2. Depression 9. Neuroleptic agent. Common side effects of atomoxetine include abdominal pain, loss of appetite, nausea, feeling tired, and dizziness.Atomoxetine is approved for use in children, adolescents, and adults.While its efficacy may be less than that of stimulant medications,The initial therapeutic effects of atomoxetine usually take 2–4 weeks to become apparent.Common side effects include abdominal pain, loss of appetite, nausea, feeling tired, and dizziness.Atomoxetine is relatively non-toxic in overdose. InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21)/t11-/m0/s1 Levosulpiride is primarily indicated in conditions like Anxiety, Depression, Gastro-esophageal reflux disease, Irritable bowel syndrome, Schizophrenia, Tourette's syndrome, dyspeptic syndrome, essential cephalgia, and can also be given in adjunctive therapy as an alternative drug of choice in Peptic ulcer, Vertigo. Levosulpiride does not appear to be available in North America.