In addition, the use of lithium orotate may cause adverse effects similar to those that result from lithium toxicity.
In this compound, lithium is non-covalently bound to an orotate ion, rather than to a carbonate or other ion, and like other salts, dissociates in solution to produce free lithium ions. Severe toxicity may cause confusion, kidney failure, low blood pressure, coma, and occasionally death. Concerns have been raised in medical literature after a case report of a patient who required medical attention after taking an overdose of lithium orotate supplement.InChI=1S/C5H4N2O4.Li/c8-3-1-2(4(9)10)6-5(11)7-3;/h1H,(H,9,10)(H2,6,7,8,11);/q;+1/p-1 The combination of lithium bound to orotic acid is like brain food that supports a stable, balanced mental state, and overall neurological health. It's also important to note that self-treating a chronic condition (such as bipolar disorder) with lithium orotate, and avoiding or delaying standard care, may have serious consequences.Learn the best ways to manage stress and negativity in your life.Menegueti MG, Basile-filho A, Martins-filho OA, Auxiliadora-martins M.
Lithium orotate is a more bioavailable form of lithium that should have essentially the same effects. Ⓒ 2020 About, Inc. (Dotdash) — All rights reservedHow Different Mental Illnesses Are Diagnosed and TreatedThe Health Benefits of Passionflower for Anxiety and Other Health ConditionsUsing Galphimia From Traditional Uses to Modern ResearchDon't Overlook These Natural Ways to Improve Memory
As previously stated, lithium intake appears to be effective even at low doses, and this may account for lithium orotates claimed effectiveness.Lithium orotate's safety remains in question. Lithium orotate is an over-the-counter nutritional supplement that offers many benefits for mind and body. Due to the health risks associated with lithium toxicity, safe use of lithium requires periodic blood-testing to ensure that toxic levels of the drug are not being reached. Lithium Orotate provides nutritional support to promote a balanced mood, and a healthy response to stress. Major medical research has not been conducted on lithium orotate since the 1980s due to its patent status and the abundant availability of lithium carbonate.
H2O. Also, lithium may interact with a variety of medications such as ACE inhibitors, anticonvulsants, antidepressants, calcium channel blockers, dextromethorphan, loop diuretics, meperidine, methyldopa, and monoamine oxidase inhibitors (MAOIs). In the human body, orotic acid can be produced from microorganisms found in the intestines.
Lithium Orotate 5 mg 2 or 3 times per day.
Nootropics Expert Recommendation.
Read our Available in dietary supplement form, lithium orotate is touted as a natural treatment for a wide range of
Although a number of studies published in the 1970s and 1980s determined that lithium orotate may offer certain benefits, more recent research on lithium orotate is lacking. Lithium is said to treat and prevent manic episodes by reducing abnormal brain activity. Ⓒ 2020 About, Inc. (Dotdash) — All rights reserved Low-dose lithium orotate boosts cognitive function. The available research on lithium orotate includes a small study published in the journal In a study published in the Journal of Affective Disorders and conducted by Dr. Linda Franchini et al., lithium orotate was one of the potential outpatient treatments for mood disorders.
In alternative medicine, lithium orotate is sometimes promoted as an alternative to lithium, a medication prescribed to treat and prevent episodes of mania in people with Although orotic acid is sometimes referred to as vitamin B13, it's not actually considered a vitamin. In alternative medicine, lithium orotate is sometimes promoted as an alternative to lithium, a medication prescribed to treat and prevent episodes of mania in people with bipolar disorder.
Verywell Mind uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. The half life for Lithium Orotate is 24 hours. Due to a lack of research, little is known about the safety of lithium orotate supplements. Over-the-counter lithium orotate is promoted as a health supplement for use as a low-dose source of lithium; however, very limited clinical evidence exists to support use. 97 ($0.08/Count) Due to safety concerns, using lithium orotate without the supervision of a healthcare professional is strongly discouraged. Lithium orotate is a substance that consists of lithium (an alkali metal) and orotic acid (a compound produced naturally in the body). It’s important to note that much of this review of the nootropic lithium orotate is based on research done on the pharmacological research done on the prescribed drug lithium in the form of lithium carbonate. I recommend and use Lithium Orotate by Advanced Research which was formulated by Dr. Hans Nieper. However, there's some evidence that lithium orotate may have some toxic effects.
Along with nausea and vomiting, these adverse effects include cardiac arrhythmias and neurological problems. While lithium orotate is capable of providing lithium to the body, like lithium carbonate and other lithium salts, there are no In 1973, Nieper reported that lithium orotate contained 3.83 mg of elemental lithium per 100 mg and lithium carbonate contained 18.8 mg of elemental lithium per 100 mgThe pharmacokinetics of lithium orotate in human brains is poorly documented, and there is no known mechanism by which orotate ions could alter the pharmacokinetics of dissociated lithium ions.
Noncontrolled studies have examined the use of low-dose lithium orotate in the treatment of alcoholism, migraines, and depression associated with bipolar disorder. Discussed below are some of the most popular lithium orotate benefits; 1. Lithium orotate（5266-20-6） has been proved to be neuroprotective and to boost cognitive function. It is marketed as a dietary supplement, though only barely researched between 1973–1986 to treat certain medical conditions, such as alcoholism and Alzheimer's disease. Lithium Orotate Half Life. For instance, a 2007 report published in the There's some concern that the use of lithium orotate may lower kidney function. In alternative medicine, lithium orotate is purported to treat and prevent the following conditions: Top 10 Benefits of Lithium Orotate. Research on the health effects of lithium orotate is very limited.