Dosage of drugs is not considered in the study. The RCA veinous graft collapsed this month and a DES was placed last week. home > drug interactions checker > clopidogrel oral and omeprazole oral interactions clopidogrel oral brand names and other generic formulations include: Plavix Oral.

Other drugs that have the same active ingredients (e.g. The combination use of clopidogrel and certain types of PPIs (omeprazole, lansoprazole, esomeprazole, pantoprazole) increases the risk of MACE in patients with coronary artery disease. Or they may prescribe clopidogrel instead of daily low dose aspirin if you have problems with aspirin. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.Serious. A similar reduction in antiplatelet activity was observed with esomeprazole when given concomitantly with Plavix. Was on Plavix and Omeprazole for quite a while. generic drugs) are not considered. Your doctor may want to change your proton pump inhibitor or cimetidine to a different medicine.Your healthcare professionals may already be aware of this interaction and may be monitoring you for it. … This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.Things to remember when you fill your prescription.WebMD does not provide medical advice, diagnosis or treatment. The clopidogrel-omeprazole interaction was also analyzed in a prospective clinical study, “Clopidogrel and Optimization of Gastrointestinal Events” (COGENT). doctor or pharmacist) for more information.Some proton pump inhibitors and cimetidine may slow down how quickly your liver processes clopidogrel to its active form.Make sure your healthcare professionals (e.g. Some reports may have incomplete information.Patients can bring a copy of the report to their healthcare provider to ensure that all drug risks and benefits are fully discussed and understood. Dexlansoprazole, lansoprazole, and … FDA is alerting the public to new safety information concerning an interaction between clopidogrel , an anti-clotting medication, and omeprazole (Prilosec/Prilosec OTC), a proton pump inhibitor (PPI) used to reduce stomach acid. Use of this site constitutes acceptance of eHealthMe.com's terms of service and privacy policy. In clinical studies, omeprazole was shown to reduce significantly the antiplatelet activity of Plavix when given concomitantly or 12 hours apart. The proton pump inhibitor, omeprazole, but not lansoprazole or pantoprazole, is a metabolism-dependent inhibitor of CYP2C19: implications for coadministration with clopidogrel… New data show that when clopidogrel and omeprazole are taken together, the effectiveness of clopidogrel is reduced. The study is created by eHealthMe based on reports of 5,564 people who take Omeprazole and Plavix from the FDA, and is updated regularly. Your doctor may prescribe daily low dose aspirin (75mg tablets) to take together with clopidogrel. Only in the RMs of CYP2C19, PPIs were associated with significantly increased MACE in patients coadministered with …

Avoid concomitant use of Plavix with omeprazole or esomeprazole. These medicines may interact and cause very harmful effects. The study is based on omeprazole and clopidogrel bisulfate (the active ingredients of Omeprazole and Plavix, respectively), and Omeprazole and Plavix (the brand names). It is recommended that patients use the information presented as a part of a broader decision-making process.If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.© 2020 eHealthMe.com.