Hence, use Rosuvastatin exposure is not influenced by mild- to moderate renal impairment (CLAspirin should be avoided in patients with severe hepatic insufficiency. Keep bottle tightly closed in order to protect from moisture.Blisters of aluminium laminate/aluminium foil of 7, 14, 15, 20, 28, 30, 42, 50, 56, 60, 84, 90, 98 and 100 tabletsAny unused medicinal product or waste material should be disposed of in accordance with local requirements.Horizon Place, 600 Capability Green, Luton, Bedfordshire, LU1 3LUTo bookmark a medicine you must sign up and log in.To view the changes to a medicine you must sign up and log in. The change from baseline was -0.0014 mm/year (-0.12%/year (non-significant)) for rosuvastatin compared to a progression of +0.0131 mm/year (1.12%/year (p<0.0001)) for placebo. It may be a contributory factor in the causation of Reye's syndrome in some children. Although not all adverse reactions identified in the adult population have been observed in clinical trials of children and adolescent patients, the same warnings and precautions for adults should be considered for children and adolescents. Due to this fact, patients who tend to have reduced uric acid excretion may experience gout attacks.

The maximum response is usually achieved by 4 weeks and is maintained after that.Crestor is effective in adults with hypercholesterolaemia, with and without hypertriglyceridaemia, regardless of race, sex or age and in special populations such as diabetics or patients with familial hypercholesterolaemia.From pooled phase III data, Crestor has been shown to be effective at treating the majority of patients with type IIa and IIb hypercholesterolaemia (mean baseline LDL-C about 4.8 mmol/L) to recognised European Atherosclerosis Society (EAS; 1998) guideline targets; about 80% of patients treated with 10 mg reached the EAS targets for LDL-C levels (<3 mmol/L).In a large study, 435 patients with heterozygous familial hypercholesterolaemia were given Crestor from 20 mg to 80 mg in a force-titration design.

You can also report side effects directly via the national pharmacovigilance program of India by calling on 1800 180 3024.By reporting side-effects, you can help provide more information on the safety of this product.There is no specific treatment in the event of overdose.

In situations where co-administration of these medicinal products with Crestor is unavoidable, the benefit and the risk of concurrent treatment and Crestor dosing adjustments should be carefully considered (see section 4.5).- in patients with hypersensitivity to rosuvastatin or to any of the excipients.- in patients with active liver disease including unexplained, persistent elevations of serum transaminases and any serum transaminase elevation exceeding 3 times the upper limit of normal (ULN).- in patients with severe renal impairment (creatinine clearance <30 ml/min).- during pregnancy and lactation and in women of childbearing potential not using appropriate contraceptive measures.The 40 mg dose is contraindicated in patients with pre-disposing factors for myopathy/rhabdomyolysis.

In the Justification for the Use of Statins in Primary Prevention: An Intervention Trial Evaluating Rosuvastatin (JUPITER) study, the effect of rosuvastatin on the occurrence of major atherosclerotic cardiovascular disease events was assessed in 17,802 men (≥50 years) and women (≥60 years).Study participants were randomly assigned to placebo (n=8901) or rosuvastatin 20 mg once daily (n=8901) and were followed for a mean duration of 2 years.LDL-cholesterol concentration was reduced by 45% (p<0.001) in the rosuvastatin group compared to the placebo group. Use of salicylates at high doses may lead to rashes, platelet abnormalities and bleeding in nursing infants. Whenever possible, alternative medications should be considered, and, if necessary, consider temporarily discontinuing Crestor therapy. Patients who consume three or more alcoholic drinks every day should be counselled about the bleeding risks involved with chronic, heavy alcohol use while taking Increased systemic exposure to rosuvastatin has been observed in subjects receiving rosuvastatin concomitantly with various protease inhibitors in combination with ritonavir.

Read About Lipicard 200mg (100 Capsules Pack) made by USV, Uses, MRP, Substitutes @Drugssquare.com Rosuvastatin also lowers the LDL-C/HDL-C, total C/HDL-C and non-HDL-C/HDL-C and the ApoB/ApoA-1 ratios.Aspirin is a more potent inhibitor of both prostaglandin synthesis and platelet aggregation than other salicylic acid derivatives.